Question 1

A healthy immune system destroys cancer cells with

Accepted Answer

A)  CTLs and activated macrophages. 
B)  activated macrophages. 
C)  tumor-specific antigens. 
D)  CD+ T cells. 
E)  CTLs. 
A)  CTLs and activated macrophages. 
B)  activated macrophages. 
C)  tumor-specific antigens. 
D)  CD+ T cells. 
E)  CTLs.

Question 2

Treatment with certain drugs to reduce transplant rejection can cause

Accepted Answer

A)  immunosuppression. 
B)  immunologic surveillance. 
C)  immunotherapy. 
D)  autoimmunity. 
E)  immunologic enhancement. 
A)  immunosuppression. 
B)  immunologic surveillance. 
C)  immunotherapy. 
D)  autoimmunity. 
E)  immunologic enhancement.

Question 3

Figure 19.1
  
-In immune complex reaction shown in Figure 19.1, what is the end result of the reaction?

Accepted Answer

A)  Complement is activated. 
B)  Neutrophils are attracted and release enzymes. 
C)  Antibodies destroy neutrophils. 
D)  IgG is directed against cell membrane antigens. 
E)  Endothelial cells are damaged. 
A)  Complement is activated. 
B)  Neutrophils are attracted and release enzymes. 
C)  Antibodies destroy neutrophils. 
D)  IgG is directed against cell membrane antigens. 
E)  Endothelial cells are damaged.

Question 4

The number of T cells drops to below 200 cells/microliter in which phase of HIV infection?

Accepted Answer

A)  initial phase 
B)  phase 1 
C)  phase 3 
D)  phase 2 
E)  asymptomatic phase 
A)  initial phase 
B)  phase 1 
C)  phase 3 
D)  phase 2 
E)  asymptomatic phase

Question 5

Skin tests are reliable indicators for the diagnosis of food -related allergies.

Accepted Answer

A) True 
 B)False

Question 6

In rheumatoid arthritis, IgM, IgG, and complement deposit in joints. This is an example of

Accepted Answer

A)  immunosuppression. 
B)  cytotoxic autoimmunity. 
C)  immune complex autoimmunity. 
D)  cell-mediated autoimmunity. 
E)  acquired immunodeficiency. 
A)  immunosuppression. 
B)  cytotoxic autoimmunity. 
C)  immune complex autoimmunity. 
D)  cell-mediated autoimmunity. 
E)  acquired immunodeficiency.

Question 7

Rheumatoid arthritis is due to deposition of

Accepted Answer

A)  complexes of IgM and IgG and also complement in joints. 
B)  IgA antibodies in joints. 
C)  IgG and IgA complexes in joints. 
D)  IgD and IgE complexes in joints. 
E)  complement in joints. 
A)  complexes of IgM and IgG and also complement in joints. 
B)  IgA antibodies in joints. 
C)  IgG and IgA complexes in joints. 
D)  IgD and IgE complexes in joints. 
E)  complement in joints.

Question 8

Which of the following statements about human embryonic stem cells is TRUE?

Accepted Answer

A)  They are pluripotent and typically obtained from the blastocyst stage of embryonic development. 
B)  They are pluripotent. 
C)  They are typically obtained from the zygote stage of embryonic development. 
D)  They are obtained in great numbers from umbilical cords of newborns. 
E)  They express no MHC II antigens. 
A)  They are pluripotent and typically obtained from the blastocyst stage of embryonic development. 
B)  They are pluripotent. 
C)  They are typically obtained from the zygote stage of embryonic development. 
D)  They are obtained in great numbers from umbilical cords of newborns. 
E)  They express no MHC II antigens.

Question 9

Which of the following is a possible outcome of an HIV infection?

Accepted Answer

A)  There may be persistent yeast infections. 
B)  Infection may initially be asymptomatic. 
C)  The disease does not progress to AIDS. 
D)  Virions may remain latent. 
E)  All of the answers are correct. 
A)  There may be persistent yeast infections. 
B)  Infection may initially be asymptomatic. 
C)  The disease does not progress to AIDS. 
D)  Virions may remain latent. 
E)  All of the answers are correct.

Question 10

All of the following are considered examples of type I hypersensitivity EXCEPT

Accepted Answer

A)  dust allergies. 
B)  pollen allergies. 
C)  transplant rejections. 
D)  asthma. 
E)  penicillin allergic reactions. 
A)  dust allergies. 
B)  pollen allergies. 
C)  transplant rejections. 
D)  asthma. 
E)  penicillin allergic reactions.

Question 11

All of the following lead to drug-induced thrombocytopenic purpura. Which occurs first?

Accepted Answer

A)  Antibodies and complement react with platelets. 
B)  Platelets are destroyed. 
C)  Purpura occurs on the skin. 
D)  Antibodies against haptens are formed. 
E)  Drug binds to platelets. 
A)  Antibodies and complement react with platelets. 
B)  Platelets are destroyed. 
C)  Purpura occurs on the skin. 
D)  Antibodies against haptens are formed. 
E)  Drug binds to platelets.

Question 12

Symptoms of delayed cell-mediated reactions are due to

Accepted Answer

A)  IgE antibodies. 
B)  antigens. 
C)  neutrophils. 
D)  cytokines. 
E)  IgG antibodies. 
A)  IgE antibodies. 
B)  antigens. 
C)  neutrophils. 
D)  cytokines. 
E)  IgG antibodies.

Question 13

Differentiate type II from type III hypersensitivity reactions.

Accepted Answer

Type II and Type III hypersensitivity re

Question 14

Even though AIDS is an infectious disease caused by a virus, why is it also considered an immunodeficiency disease?

Accepted Answer

AIDS, which stands for Acquired Immunode

Question 15

All of the following pertain to serological tests EXCEPT

Accepted Answer

A)  they are used to test for specific HLAs on lymphocytes. 
B)  they can be used to diagnose various diseases. 
C)  they can detect antibodies but not antigens. 
D)  they are used to detect compatible tissues for transplantation. 
E)  reactions can be detected by uptake of trypan blue by damaged cells. 
A)  they are used to test for specific HLAs on lymphocytes. 
B)  they can be used to diagnose various diseases. 
C)  they can detect antibodies but not antigens. 
D)  they are used to detect compatible tissues for transplantation. 
E)  reactions can be detected by uptake of trypan blue by damaged cells.

Question 16

Immunodeficiencies are a result of all of the following EXCEPT

Accepted Answer

A)  DiGeorge syndrome. 
B)  Hodgkinʹs disease. 
C)  cyclosporine. 
D)  HIV infection. 
E)  autoimmune diseases. 
A)  DiGeorge syndrome. 
B)  Hodgkinʹs disease. 
C)  cyclosporine. 
D)  HIV infection. 
E)  autoimmune diseases.

Question 17

Xenotransplantation is an effective alternative to using isografts.

Accepted Answer

A) True 
 B)False

Question 18

Figure 19.1
  
-In immune complex reaction shown in Figure 19.1, what is the small, circular/spherical structure labeled ʺaʺ?

Accepted Answer

A)  antigen 
B)  mast cell 
C)  antibody 
D)  complement 
E)  neutrophil 
A)  antigen 
B)  mast cell 
C)  antibody 
D)  complement 
E)  neutrophil

Question 19

HIV can evade host antibodies by

Accepted Answer

A)  causing cell-to-cell fusion. 
B)  remaining an inactive provirus, causing cell to cell fusion, and virions remaining latent in vacuoles. 
C)  virions remaining latent in vacuoles. 
D)  remaining an inactive provirus. 
E)  lowering the CD4+ cell count. 
A)  causing cell-to-cell fusion. 
B)  remaining an inactive provirus, causing cell to cell fusion, and virions remaining latent in vacuoles. 
C)  virions remaining latent in vacuoles. 
D)  remaining an inactive provirus. 
E)  lowering the CD4+ cell count.

Question 20

Individuals who do not express CCR5 are highly resistant to infection by HIV.

Accepted Answer

A) True 
 B)False

Exam 19: Disorders Associated With the Immune System

A healthy immune system destroys cancer cells with

Treatment with certain drugs to reduce transplant rejection can cause

Figure 19.1 -In immune complex reaction shown in Figure 19.1, what is the end result of the reaction?

The number of T cells drops to below 200 cells/microliter in which phase of HIV infection?

Skin tests are reliable indicators for the diagnosis of food -related allergies.

In rheumatoid arthritis, IgM, IgG, and complement deposit in joints. This is an example of

Rheumatoid arthritis is due to deposition of

Which of the following statements about human embryonic stem cells is TRUE?

Which of the following is a possible outcome of an HIV infection?

All of the following are considered examples of type I hypersensitivity EXCEPT

All of the following lead to drug-induced thrombocytopenic purpura. Which occurs first?

Symptoms of delayed cell-mediated reactions are due to

Differentiate type II from type III hypersensitivity reactions.

Even though AIDS is an infectious disease caused by a virus, why is it also considered an immunodeficiency disease?

All of the following pertain to serological tests EXCEPT

Immunodeficiencies are a result of all of the following EXCEPT

Xenotransplantation is an effective alternative to using isografts.

Figure 19.1 -In immune complex reaction shown in Figure 19.1, what is the small, circular/spherical structure labeled ʺaʺ?

HIV can evade host antibodies by

Individuals who do not express CCR5 are highly resistant to infection by HIV.

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Functional Anatomy of Prokaryotic and Eukaryotic Cells

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Classification of Microorganisms

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Microbial Mechanisms of Pathogenicity

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Practical Applications of Immunology

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