Exam 18: Post-Transcriptional Regulation in Eukaryotes

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List three general pathways in which eukaryotic mRNA is typically degraded in eukaryotes.

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The discovery of RNA interference RNAi)led to its use in biotechnology and medicine.All of the following are examples of how RNAi could be used in biotechnology or medicine,EXCEPT _______.

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Compare and contrast kinases and phosphatases.

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mRNA surveillance mechanisms are necessary_______ .

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A researcher is studying plant development.She isolates a mutant and discovers that the piece of DNA that is mutated does not code for a protein.However,this piece of DNA is complimentary to a gene known to function in early embryonic plant development.The mutant she identified most likely functions as an_______. A)general transcription factor known to regulate many different genes B)ribosomal RNA rRNA) C)microRNA miRNA) D)transfer RNA tRNA) E)intron

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Describe how cells control the size of the poly- A tail on mRNA molecules in order to regulate translation initiation. Next explain how a kinase inhibitor could decrease gene expression in regards to polyadenylation? Your answer should include the following proteins in your answer: Maskin, PARN, CPEB, eIF4E, eIF4G, and Poly- A polymerase.

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Which of the following statements is most true regarding long noncoding RNAs lncRNAs ?

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Adenosine-uridine- rich elements are_______.

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A long poly- A- tail is necessary to initiate translation.Which protein binds directly to eIF4E to inhibit translation initiation?

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