Exam 24: Cancer Genetics

Which virus type results in the immediate onset of cancer phenotype upon infection of a host?

All of these are known to cause cancer EXCEPT _____.

All of the following are checkpoints in the cell cycle EXCEPT _____ .

Much has been written about p53 in terms of cancer biology.What is p53,and what is its significance?

Most p53 mutations that result in cancer are a result of loss of function in p53.Describe one method through which a gain- of- function mutation in p53 could cause cancer.

Mutations in the ras gene family induce normally quiescent cells to proceed into the replication cycle.This converts the ras gene from a _______gene to a _______ gene.

What are two properties that various types of cancer cells share?

Which category of genetic changes does not lead to the formation of oncogenes?

In what way can loss of heterozygosity lead to cancer?

Chronic myelogenous leukemia is a cancer found in white blood cells.What is its supposed genetic basis of this disease?

In what way might a virus contribute to cancer formation?

What is the significance of CDK/cyclin interactions with respect to cancer cell proliferation?

As more is learned about cancer,it has become clear that cancer,with few exceptions, _____.

Which three stages or transitions in the cell cycle seem to serve as points of control checkpoints)?

Examined cancer cells from the lungs of smokers demonstrate which of the following?

What is the name of the protein that appears to regulate the entry of cells into an S phase? This protein is also known as the "guardian of the genome."

When considered as a root cause for cancer,which of the following is linked to at least 17 types of human cancer?

What is the name of the protein that combines with cyclins to exert local control of the cell cycle?

Describe the general relationship that may exist between mutations and cancer.

Most cancer- causing animal viruses are RNA viruses called _____ .