Exam 28: DNA Forensics

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Mitochondrial DNA profiling is useful in developing DNA profiles from samples that are in less than ideal condition.What is a major limitation of using mitochondrial DNA profiling?

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DNA phenotyping represents an emerging technology that uses SNPs to determine physical features.Describe why DNA phenotyping faces skepticism in court rooms and from other scientists with regard to its accuracy.

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DNA phenotyping faces scrutiny and skepticism due to its reliance on multiple genes as well as multiple SNPs in those genes to provide a rather low probability of a correct identification.

Single- nucleotide polymorphisms SNPs are being used more and more in forensic analysis yet have not been fully embraced.However,SNPs have found an exemplary use in which of the following fields?

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One of the advantages of STR profiling over VNTR profiling is that_______ .

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Present evidence supporting the argument that Y chromosome STR profiling is not sufficient for proper DNA profiling.

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Mitochondrial DNA profiling is used to trace the maternal side of family trees.Why is this done using mtDNA?

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Provide support for using the product rule in generating a high confidence that an individual has a unique DNA profile using multiple STRs.

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When using DNA profiling in prosecuting criminal cases,lawyers must be very thorough in their investigation of the DNA evidence.Which of the following could cause issues with the DNA evidence presented in a court case?

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Justify the FBI's use of only 20 short tandem repeats STRs as their core set of STRs for forensic analysis.

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Using the values in TABLE ST 2.2; what is the expected genotype frequency for the two loci profile consisting of D8S1179 and D5S818?

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Mitochondrial DNA profiling is primarily used to differentiate_______ .

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Which of the following contribute to an increased probability of a random match of a DNA profile in a population?

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Why does DNA profiling pose potential ethical problems when a partial match occurs in CODIS?

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There are several concerns with using DNA profiling in forensics with the advent of cheaper synthesis methods for DNA.Propose a mechanism to determine if crime scene evidence is natural or synthetic.

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STRs are repeated elements in the genome.They have _______nucleotides per repeat compared to VNTRs.

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The development of which biotechnology revolutionized the field of DNA forensics?

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DNA phenotyping poses several concerns as an emerging technology.Which of the following is not a concern with DNA phenotyping?

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CODIS Combined DNA Index System is a database that contains DNA profiles from all of the following EXCEPT_______ .

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Explain why Identical twins can have the same STRs in a DNA profile yet still exhibit differing phenotypes.

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VNTRs are useful in DNA forensics because_______ .

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