Question 1

Which hepatitis virus commonly leads to chronic hepatitis and cirrhosis, often requiring a liver transplant, and causes a high risk for development of liver cancer?

Accepted Answer

A)  Hepatitis A 
B)  Hepatitis D 
C)  Hepatitis C 
D)  Hepatitis E 
A)  Hepatitis A 
B)  Hepatitis D 
C)  Hepatitis C 
D)  Hepatitis E

Question 2

What virus is the most common cause of arboviral encephalitis in the world?

Accepted Answer

A)  Ebola virus 
B)  Japanese encephalitis (J
E)  virus 
C)  Venezuelan equine encephalitis virus 
D)  Eastern equine encephalitis virus 
A)  Ebola virus 
B)  Japanese encephalitis (J
E)  virus 
C)  Venezuelan equine encephalitis virus 
D)  Eastern equine encephalitis virus

Question 3

What is the correct sequence of viral infection of naked viruses?

Accepted Answer

A)  Attachment, penetration, replication, cell lysis 
B)  Penetration, attachment, replication, cell lysis 
C)  Replication, penetration, attachment, cell lysis 
D)  Penetration, replication, attachment, cell lysis 
A)  Attachment, penetration, replication, cell lysis 
B)  Penetration, attachment, replication, cell lysis 
C)  Replication, penetration, attachment, cell lysis 
D)  Penetration, replication, attachment, cell lysis

Question 4

Which virus is a bloodborne pathogen?

Accepted Answer

A)  Hepatitis A virus 
B)  Rabies virus 
C)  Hepatitis C virus 
D)  Norovirus 
A)  Hepatitis A virus 
B)  Rabies virus 
C)  Hepatitis C virus 
D)  Norovirus

Question 5

Which hepatitis virus is spread by the fecal-oral route?

Accepted Answer

A)  Hepatitis B 
B)  Hepatitis A 
C)  Hepatitis C 
D)  Hepatitis D 
A)  Hepatitis B 
B)  Hepatitis A 
C)  Hepatitis C 
D)  Hepatitis D

Question 6

All of the following are identifiable viral agents of gastroenteritis, except

Accepted Answer

A)  Norwalk. 
B)  rotavirus. 
C)  enteric adenoviruses. 
D)  CMV. 
A)  Norwalk. 
B)  rotavirus. 
C)  enteric adenoviruses. 
D)  CMV.

Question 7

Symptomatic congenital infection with CMV includes all the following symptoms, except

Accepted Answer

A)  hepatosplenomegaly. 
B)  microcephaly. 
C)  chorioretinitis. 
D)  meningitis. 
A)  hepatosplenomegaly. 
B)  microcephaly. 
C)  chorioretinitis. 
D)  meningitis.

Question 8

What are giant multinucleated cells formed from cell fusion as a result of viral infection?

Accepted Answer

A)  Giant cells 
B)  Macrophages 
C)  Glial cells 
D)  Syncytia 
A)  Giant cells 
B)  Macrophages 
C)  Glial cells 
D)  Syncytia

Question 9

What virus causes genital herpes?

Accepted Answer

A)  Human herpesvirus 6 
B)  CMV 
C)  Herpes simplex virus type 2 
D)  Human herpesvirus 
A)  Human herpesvirus 6 
B)  CMV 
C)  Herpes simplex virus type 2 
D)  Human herpesvirus

Question 10

Which one of the following viruses causes a viral hemorrhagic fever?

Accepted Answer

A)  Sin Nombre virus 
B)  Venezuelan equine encephalitis virus 
C)  Rhabdovirus 
D)  Ebola virus 
A)  Sin Nombre virus 
B)  Venezuelan equine encephalitis virus 
C)  Rhabdovirus 
D)  Ebola virus

Question 11

Adenoviruses produce all the following types of infections, except

Accepted Answer

A)  acute hemorrhagic cystitis. 
B)  meningitis. 
C)  acute respiratory distress. 
D)  epidemic keratoconjunctivitis. 
A)  acute hemorrhagic cystitis. 
B)  meningitis. 
C)  acute respiratory distress. 
D)  epidemic keratoconjunctivitis.

Question 12

What disease does the varicella zoster virus (VZV) cause?

Accepted Answer

A)  Mumps 
B)  Genital warts 
C)  Chickenpox 
D)  Rubella 
A)  Mumps 
B)  Genital warts 
C)  Chickenpox 
D)  Rubella

Question 13

What infectious agent causes Creutzfeldt-Jakob disease, Kuru, and "mad cow" disease?

Accepted Answer

A)  Prion 
B)  Bacteria 
C)  Virus 
D)  Parasite 
A)  Prion 
B)  Bacteria 
C)  Virus 
D)  Parasite

Question 14

Presence of this HBV serologic marker indicates a person is highly infectious.

Accepted Answer

A)  HBs antigen 
B)  HBc antigen 
C)  Anti-HBs 
D)  Anti-HBc 
A)  HBs antigen 
B)  HBc antigen 
C)  Anti-HBs 
D)  Anti-HBc

Question 15

Poliovirus is transmitted primarily by

Accepted Answer

A)  aerosol. 
B)  blood. 
C)  urine. 
D)  fecal-oral. 
A)  aerosol. 
B)  blood. 
C)  urine. 
D)  fecal-oral.

Question 16

Which of the following describes cytopathic effects seen in viral culture?

Accepted Answer

A)  The way viruses kill the infected host cell 
B)  The visual changes produced in an infected cell by a virus 
C)  The tears that the virus puts in an infected host cell's membrane 
D)  The way the virus lyses the infected cell after all the new virus particles are formed and ready to be released. 
A)  The way viruses kill the infected host cell 
B)  The visual changes produced in an infected cell by a virus 
C)  The tears that the virus puts in an infected host cell's membrane 
D)  The way the virus lyses the infected cell after all the new virus particles are formed and ready to be released.

Question 17

All the following methods are used by the laboratory to diagnose viral infections, except

Accepted Answer

A)  nucleic acid amplification. 
B)  direct detection. 
C)  growth on artificial media. 
D)  serologic assays. 
A)  nucleic acid amplification. 
B)  direct detection. 
C)  growth on artificial media. 
D)  serologic assays.

Question 18

Which of the following is the best description of a primary cell culture?

Accepted Answer

A)  It is a culture where tissue is removed from an animal, arranged in a monolayer, and in which very little cell division occurs. 
B)  It is a culture which contains cells that can divide, but passage is limited to 50 generations. 
C)  It contains cells with a variable number of chromosomes and can be subcultured indefinitely. 
D)  This describes the only cells the specimen will be plated on. 
A)  It is a culture where tissue is removed from an animal, arranged in a monolayer, and in which very little cell division occurs. 
B)  It is a culture which contains cells that can divide, but passage is limited to 50 generations. 
C)  It contains cells with a variable number of chromosomes and can be subcultured indefinitely. 
D)  This describes the only cells the specimen will be plated on.

Question 19

Which of the following is the description of continuous cell cultures?

Accepted Answer

A)  It is a culture where tissue is removed from an animal, forms a monolayer, and in which very little cell division occurs. 
B)  It is a cell culture that can divide, but passage is limited to 50 generations. 
C)  Cells often have variable numbers of chromosomes and can be subcultured indefinitely. 
D)  This describes the only cells the specimen will be plated on. 
A)  It is a culture where tissue is removed from an animal, forms a monolayer, and in which very little cell division occurs. 
B)  It is a cell culture that can divide, but passage is limited to 50 generations. 
C)  Cells often have variable numbers of chromosomes and can be subcultured indefinitely. 
D)  This describes the only cells the specimen will be plated on.

Question 20

What virus causes the measles?

Accepted Answer

A)  Mumps 
B)  RSV 
C)  Herpes virus 6 
D)  Rubeola virus 
A)  Mumps 
B)  RSV 
C)  Herpes virus 6 
D)  Rubeola virus

Exam 29: Clinical Virology

Which hepatitis virus commonly leads to chronic hepatitis and cirrhosis, often requiring a liver transplant, and causes a high risk for development of liver cancer?

What virus is the most common cause of arboviral encephalitis in the world?

What is the correct sequence of viral infection of naked viruses?

Which virus is a bloodborne pathogen?

Which hepatitis virus is spread by the fecal-oral route?

All of the following are identifiable viral agents of gastroenteritis, except

Symptomatic congenital infection with CMV includes all the following symptoms, except

What are giant multinucleated cells formed from cell fusion as a result of viral infection?

What virus causes genital herpes?

Which one of the following viruses causes a viral hemorrhagic fever?

Adenoviruses produce all the following types of infections, except

What disease does the varicella zoster virus (VZV) cause?

What infectious agent causes Creutzfeldt-Jakob disease, Kuru, and "mad cow" disease?

Presence of this HBV serologic marker indicates a person is highly infectious.

Poliovirus is transmitted primarily by

Which of the following describes cytopathic effects seen in viral culture?

All the following methods are used by the laboratory to diagnose viral infections, except

Which of the following is the best description of a primary cell culture?

Which of the following is the description of continuous cell cultures?

What virus causes the measles?

Bacterial Cell Structure, Physiology, Metabolism, and Genetics

Hostparasite Interaction

The Laboratory Role in Infection Control

Control of Microorganisms

Performance Improvement in the Microbiology Laboratory

Specimen Collection and Processing

Microscopic Examination of Materials From Infected Sites

Use of Colony Morphology for the Presumptive Identification of Microorganisms

Biochemical Identification of Gram-Negative Bacteria

Immunodiagnosis of Infectious Diseases

Applications of Molecular Diagnostics

Antimicrobial Agent Mechanisms of Action and Resistance Mechanisms

Antimicrobial Susceptibility Testing

Staphylococci

Streptococcus, Enterococcus, and Other Catalase-Negative, Gram-Positive Cocci

Aerobic Gram-Positive Bacilli

Neisseria Species and Moraxella Catarrhalis

Haemophilus, Hacek, Legionella, and Other Fastidious Gram-Negative Bacilli

Enterobacteriaceae

Vibrio, Aeromonas, and Campylobacter Species

Nonfermenting and Miscellaneous Gram-Negative Bacilli

Anaerobes of Clinical Importance

The Spirochetes

Chlamydia, Rickettsia, and Similar Organisms

Mycoplasma and Ureaplasma

Mycobacterium Tuberculosis and Nontuberculous Mycobacteria

Medically Significant Fungi

Diagnostic Parasitology

Agents of Bioterror and Forensic Microbiology

Biofilms: Architects of Disease

Upper and Lower Respiratory Tract Infections

Skin and Soft Tissue Infections

Gastrointestinal Infections and Food Poisoning

Infections of the Central Nervous System

Bacteremia and Sepsis

Urinary Tract Infections

Genital Infections and Sexually Transmitted Infections

Infections in Special Populations

Zoonotic Diseases

Ocular Infections

Filters