Question 1

When is the best time to collect a specimen for culture from a patient suspected of having a viral disease?

Accepted Answer

A)  1 week after onset of symptoms 
B)  5 days after onset of symptoms 
C)  Less than 3 days after onset of symptoms 
D)  2 weeks after onset of symptoms 
A)  1 week after onset of symptoms 
B)  5 days after onset of symptoms 
C)  Less than 3 days after onset of symptoms 
D)  2 weeks after onset of symptoms C

Question 2

What is an unsuitable storage temperature for viruses because it allows the development of ice crystals?

Accepted Answer

A)  4° C 
B)  -10° C 
C)  -20° C 
D)  -70° C 
A)  4° C 
B)  -10° C 
C)  -20° C 
D)  -70° C C

Question 3

What type of cancer is associated with human papilloma virus (HPV)?

Accepted Answer

A)  Lung 
B)  Ovarian 
C)  Skin 
D)  Cervical 
A)  Lung 
B)  Ovarian 
C)  Skin 
D)  Cervical D

Question 4

The cytopathic effect demonstrating intranuclear inclusions is associated with

Accepted Answer

A)  influenza virus. 
B)  respiratory syncytial virus (RSV). 
C)  cytomegalovirus (CMV). 
D)  rotavirus. 
A)  influenza virus. 
B)  respiratory syncytial virus (RSV). 
C)  cytomegalovirus (CMV). 
D)  rotavirus.

Question 5

The genome of a virus is composed of?

Accepted Answer

A)  single-stranded DNA. 
B)  RNA. 
C)  double-stranded DNA. 
D)  Any of the above 
A)  single-stranded DNA. 
B)  RNA. 
C)  double-stranded DNA. 
D)  Any of the above

Question 6

Which cancer is associated with EBV?

Accepted Answer

A)  Hepatocellular carcinoma 
B)  Burkitt's lymphoma 
C)  Non-Hodgkin's lymphoma 
D)  T-cell leukemia 
A)  Hepatocellular carcinoma 
B)  Burkitt's lymphoma 
C)  Non-Hodgkin's lymphoma 
D)  T-cell leukemia

Question 7

Severe acute respiratory syndrome (SARS) is caused by a

Accepted Answer

A)  coronavirus. 
B)  picornavirus. 
C)  enterovirus. 
D)  paramyxovirus. 
A)  coronavirus. 
B)  picornavirus. 
C)  enterovirus. 
D)  paramyxovirus.

Question 8

The noroviruses are most noted for producing

Accepted Answer

A)  upper respiratory tract infections. 
B)  lower respiratory tract infections. 
C)  meningitis. 
D)  gastroenteritis. 
A)  upper respiratory tract infections. 
B)  lower respiratory tract infections. 
C)  meningitis. 
D)  gastroenteritis.

Question 9

Which virus has been linked to Kaposi sarcoma?

Accepted Answer

A)  Human herpesvirus 8 
B)  CMV 
C)  Herpes simplex 
D)  Epstein-Barr 
A)  Human herpesvirus 8 
B)  CMV 
C)  Herpes simplex 
D)  Epstein-Barr

Question 10

What virus is the major cause of the common cold?

Accepted Answer

A)  Rotavirus 
B)  RSV 
C)  Rhinovirus 
D)  Norovirus 
A)  Rotavirus 
B)  RSV 
C)  Rhinovirus 
D)  Norovirus

Question 11

Complications of Epstein-Barr virus (EBV) infection include all the following, except

Accepted Answer

A)  acute glomerulonephritis. 
B)  Reye's syndrome. 
C)  thrombocytopenia purpura with hemolytic anemia. 
D)  splenic hemorrhage and rupture. 
A)  acute glomerulonephritis. 
B)  Reye's syndrome. 
C)  thrombocytopenia purpura with hemolytic anemia. 
D)  splenic hemorrhage and rupture.

Question 12

What is the most common flavivirus infection in the United States?

Accepted Answer

A)  West Nile virus 
B)  Eastern equine encephalitis virus 
C)  St. Louis encephalitis (SL
E)  
D)  Rocky Mountain spotted fever 
A)  West Nile virus 
B)  Eastern equine encephalitis virus 
C)  St. Louis encephalitis (SL
E)  
D)  Rocky Mountain spotted fever

Question 13

What virus causes Hantavirus pulmonary syndrome?

Accepted Answer

A)  Sin Nombre virus 
B)  Dobrava virus 
C)  Junin 
D)  Lassa 
A)  Sin Nombre virus 
B)  Dobrava virus 
C)  Junin 
D)  Lassa

Question 14

Which serologic marker would be expected to be found in the serum of someone successfully vaccinated against hepatitis B virus (HBV)?

Accepted Answer

A)  Anti-HBe 
B)  Anti-HBs 
C)  Anti-HBc 
D)  Anti-HDV 
A)  Anti-HBe 
B)  Anti-HBs 
C)  Anti-HBc 
D)  Anti-HDV

Question 15

The most common route of infection of laboratory workers with HBV and HIV is

Accepted Answer

A)  mucous membranes. 
B)  inhalation. 
C)  ingestion. 
D)  needlestick. 
A)  mucous membranes. 
B)  inhalation. 
C)  ingestion. 
D)  needlestick.

Question 16

What viral genus causes rabies?

Accepted Answer

A)  Lyssavirus 
B)  Lassa virus 
C)  Marburg virus 
D)  Calicivirus 
A)  Lyssavirus 
B)  Lassa virus 
C)  Marburg virus 
D)  Calicivirus

Question 17

What requirements do viruses have for replication?

Accepted Answer

A)  They must be inside a living cell. 
B)  They must be in an environment where all the necessary amino acids are present. 
C)  They can use a dead cell to replicate. 
D)  They require dead, decaying flesh so that all amino acids and enzymes are present. 
A)  They must be inside a living cell. 
B)  They must be in an environment where all the necessary amino acids are present. 
C)  They can use a dead cell to replicate. 
D)  They require dead, decaying flesh so that all amino acids and enzymes are present.

Question 18

What type of genome do herpesviruses have?

Accepted Answer

A)  ssDNA 
B)  ssRNA 
C)  dsDNA 
D)  Both dsDNA and ssRNA 
A)  ssDNA 
B)  ssRNA 
C)  dsDNA 
D)  Both dsDNA and ssRNA

Question 19

Which of the following describes a diploid cell culture that is not a primary culture?

Accepted Answer

A)  It is a culture where tissue is removed from an animal, forms a monolayer, and very little cell division occurs. 
B)  It is a culture of cells that can divide, but passage is limited to about 50 generations. 
C)  Cells often have variable numbers of chromosomes and can be subcultured indefinitely. 
D)  This describes the only cells the specimen will be plated on. 
A)  It is a culture where tissue is removed from an animal, forms a monolayer, and very little cell division occurs. 
B)  It is a culture of cells that can divide, but passage is limited to about 50 generations. 
C)  Cells often have variable numbers of chromosomes and can be subcultured indefinitely. 
D)  This describes the only cells the specimen will be plated on.

Question 20

What is the composition of viral transport media?

Accepted Answer

A)  Amies medium with charcoal 
B)  Isotonic buffered saline with protein 
C)  Cary-Blair 
D)  Cooked meat broth 
A)  Amies medium with charcoal 
B)  Isotonic buffered saline with protein 
C)  Cary-Blair 
D)  Cooked meat broth

Exam 29: Clinical Virology

When is the best time to collect a specimen for culture from a patient suspected of having a viral disease?

What is an unsuitable storage temperature for viruses because it allows the development of ice crystals?

What type of cancer is associated with human papilloma virus (HPV)?

The cytopathic effect demonstrating intranuclear inclusions is associated with

The genome of a virus is composed of?

Which cancer is associated with EBV?

Severe acute respiratory syndrome (SARS) is caused by a

The noroviruses are most noted for producing

Which virus has been linked to Kaposi sarcoma?

What virus is the major cause of the common cold?

Complications of Epstein-Barr virus (EBV) infection include all the following, except

What is the most common flavivirus infection in the United States?

What virus causes Hantavirus pulmonary syndrome?

Which serologic marker would be expected to be found in the serum of someone successfully vaccinated against hepatitis B virus (HBV)?

The most common route of infection of laboratory workers with HBV and HIV is

What viral genus causes rabies?

What requirements do viruses have for replication?

What type of genome do herpesviruses have?

Which of the following describes a diploid cell culture that is not a primary culture?

What is the composition of viral transport media?

Bacterial Cell Structure, Physiology, Metabolism, and Genetics

Hostparasite Interaction

The Laboratory Role in Infection Control

Control of Microorganisms

Performance Improvement in the Microbiology Laboratory

Specimen Collection and Processing

Microscopic Examination of Materials From Infected Sites

Use of Colony Morphology for the Presumptive Identification of Microorganisms

Biochemical Identification of Gram-Negative Bacteria

Immunodiagnosis of Infectious Diseases

Applications of Molecular Diagnostics

Antimicrobial Agent Mechanisms of Action and Resistance Mechanisms

Antimicrobial Susceptibility Testing

Staphylococci

Streptococcus, Enterococcus, and Other Catalase-Negative, Gram-Positive Cocci

Aerobic Gram-Positive Bacilli

Neisseria Species and Moraxella Catarrhalis

Haemophilus, Hacek, Legionella, and Other Fastidious Gram-Negative Bacilli

Enterobacteriaceae

Vibrio, Aeromonas, and Campylobacter Species

Nonfermenting and Miscellaneous Gram-Negative Bacilli

Anaerobes of Clinical Importance

The Spirochetes

Chlamydia, Rickettsia, and Similar Organisms

Mycoplasma and Ureaplasma

Mycobacterium Tuberculosis and Nontuberculous Mycobacteria

Medically Significant Fungi

Diagnostic Parasitology

Agents of Bioterror and Forensic Microbiology

Biofilms: Architects of Disease

Upper and Lower Respiratory Tract Infections

Skin and Soft Tissue Infections

Gastrointestinal Infections and Food Poisoning

Infections of the Central Nervous System

Bacteremia and Sepsis

Urinary Tract Infections

Genital Infections and Sexually Transmitted Infections

Infections in Special Populations

Zoonotic Diseases

Ocular Infections

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