Question 1

Which of the following enzymes accelerates transcription?

Accepted Answer

A)  phosphorylated protein kinases 
B)  ribozymes 
C)  tRNA synthetases 
D)  all of these 
A)  phosphorylated protein kinases 
B)  ribozymes 
C)  tRNA synthetases 
D)  all of these

Question 2

Which metal is found in many transcription factors which have metal-binding fingers?

Accepted Answer

A)  Co 
B)  Cu 
C)  Fe 
D)  Zn 
A)  Co 
B)  Cu 
C)  Fe 
D)  Zn

Question 3

Approximately how many genes were believed to be in the human genome prior to 2000?

Accepted Answer

A)  10,000 
B)  30,000 
C)  100,000 
D)  1,000,000 
A)  10,000 
B)  30,000 
C)  100,000 
D)  1,000,000

Question 4

Response elements respond to which of the following?

Accepted Answer

A)  external stimuli 
B)  the TATA box 
C)  RNA polymerase 
D)  all of these 
A)  external stimuli 
B)  the TATA box 
C)  RNA polymerase 
D)  all of these

Question 5

Which of the following has a sequence that matches that of the RNA being produced?

Accepted Answer

A)  the DNA antisense strand 
B)  the DNA (−) strand 
C)  the DNA sense strand 
D)  the DNA template strand 
A)  the DNA antisense strand 
B)  the DNA (−) strand 
C)  the DNA sense strand 
D)  the DNA template strand

Question 6

Examine the following diagram.  
-Which number in the diagram represents a helicase?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
A)  1 
B)  2 
C)  3 
D)  4

Question 7

tRNA has a shape similar to which letter of the alphabet?

Accepted Answer

A)  C 
B)  L 
C)  S 
D)  T 
A)  C 
B)  L 
C)  S 
D)  T

Question 8

Examine the following diagram.  
-Which number in the diagram represents the template strand?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
A)  1 
B)  2 
C)  3 
D)  4

Question 9

Which amino acids are coded for by the most codons?

Accepted Answer

A)  glycine and alanine 
B)  glycine and leucine 
C)  leucine and serine 
D)  leucine and methionine 
A)  glycine and alanine 
B)  glycine and leucine 
C)  leucine and serine 
D)  leucine and methionine

Question 10

Which of the following is not involved in the binding of transcription factors to their gene control sequences?

Accepted Answer

A)  covalent bonding 
B)  hydrogen bonding 
C)  nonspecific ionic interactions 
D)  None, they are all involved. 
A)  covalent bonding 
B)  hydrogen bonding 
C)  nonspecific ionic interactions 
D)  None, they are all involved.

Question 11

How many sieving portions are associated with an aminoacyl-tRNA synthetase?

Accepted Answer

A)  0 
B)  1 
C)  2 
D)  3 
A)  0 
B)  1 
C)  2 
D)  3

Question 12

Which of the following is true of mutations?

Accepted Answer

A)  They will always cause a genetic disease. 
B)  They are always fatal. 
C)  They are never fatal. 
D)  Some are harmless and some quite dangerous. 
A)  They will always cause a genetic disease. 
B)  They are always fatal. 
C)  They are never fatal. 
D)  Some are harmless and some quite dangerous.

Question 13

The restriction endonuclease TaqI recognizes the sequence TCGA and cuts it between T and C on both strands. What sticky ends will be produced when TaqI cuts the sequence which follows?

Accepted Answer

A)    
B)    
C)    
D)    
A)    
B)    
C)    
D)

Question 14

How many transcription factors are required for the initiation of transcription?

Accepted Answer

A)  1 
B)  2 
C)  4 
D)  6 
A)  1 
B)  2 
C)  4 
D)  6

Question 15

Which of the following is not one of the 20 standard amino acids which are the building blocks of proteins, but is in fact sometimes found in proteins?

Accepted Answer

A)  citrulline 
B)  ornithine 
C)  selenocysteine 
D)  xanadine 
A)  citrulline 
B)  ornithine 
C)  selenocysteine 
D)  xanadine

Question 16

RNA polymerase II (pol II) catalyzes the formation of which type of RNA?

Accepted Answer

A)  mRNA 
B)  rRNA 
C)  snRNA 
D)  tRNA 
A)  mRNA 
B)  rRNA 
C)  snRNA 
D)  tRNA

Question 17

Which of the following must occur to insure that mRNA is functional?

Accepted Answer

A)  Nothing, the newly synthesized mRNA is always already functional. 
B)  The mRNA must be processed at the 3' end. 
C)  The mRNA must be processed on the 5' end. 
D)  The mRNA must be processed at both ends. 
A)  Nothing, the newly synthesized mRNA is always already functional. 
B)  The mRNA must be processed at the 3' end. 
C)  The mRNA must be processed on the 5' end. 
D)  The mRNA must be processed at both ends.

Question 18

Which of the following is not a post-translational control?

Accepted Answer

A)  chaperoning 
B)  methionine cleavage 
C)  proteasome activity 
D)  translocation 
A)  chaperoning 
B)  methionine cleavage 
C)  proteasome activity 
D)  translocation

Question 19

One of the codons for threonine is 5'ACG3'. What is the anticodon for this codon?

Accepted Answer

A)  5'GCA3' 
B)  5'ACG3' 
C)  5'CGT3' 
D)  5'CGU3' 
A)  5'GCA3' 
B)  5'ACG3' 
C)  5'CGT3' 
D)  5'CGU3'

Question 20

In which type of gene therapy is the missing gene added to cells which have been removed from a patient and the modified cells then given back to the patient?

Accepted Answer

A)  in vitro 
B)  in vivo 
C)  ex vitro 
D)  ex vivo 
A)  in vitro 
B)  in vivo 
C)  ex vitro 
D)  ex vivo

Exam 26: Gene Expression and Protein Synthesis

Which of the following enzymes accelerates transcription?

Which metal is found in many transcription factors which have metal-binding fingers?

Approximately how many genes were believed to be in the human genome prior to 2000?

Response elements respond to which of the following?

Which of the following has a sequence that matches that of the RNA being produced?

Examine the following diagram. -Which number in the diagram represents a helicase?

tRNA has a shape similar to which letter of the alphabet?

Examine the following diagram. -Which number in the diagram represents the template strand?

Which amino acids are coded for by the most codons?

Which of the following is not involved in the binding of transcription factors to their gene control sequences?

How many sieving portions are associated with an aminoacyl-tRNA synthetase?

Which of the following is true of mutations?

The restriction endonuclease TaqI recognizes the sequence TCGA and cuts it between T and C on both strands. What sticky ends will be produced when TaqI cuts the sequence which follows?

How many transcription factors are required for the initiation of transcription?

Which of the following is not one of the 20 standard amino acids which are the building blocks of proteins, but is in fact sometimes found in proteins?

RNA polymerase II (pol II) catalyzes the formation of which type of RNA?

Which of the following must occur to insure that mRNA is functional?

Which of the following is not a post-translational control?

One of the codons for threonine is 5'ACG3'. What is the anticodon for this codon?

In which type of gene therapy is the missing gene added to cells which have been removed from a patient and the modified cells then given back to the patient?

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