Question 1

Where in a T-cell receptor does binding to the antigen occur?

Accepted Answer

A)  in the constant region 
B)  in the variable region 
C)  in either the constant or the variable region 
D)  in both the regions simultaneously 
A)  in the constant region 
B)  in the variable region 
C)  in either the constant or the variable region 
D)  in both the regions simultaneously

Question 2

The enzyme GILT acts on which of the following types of antigens?

Accepted Answer

A)  nucleic acids 
B)  polysaccharides 
C)  both a and b 
D)  neither a nor b 
A)  nucleic acids 
B)  polysaccharides 
C)  both a and b 
D)  neither a nor b

Question 3

Based on all possible combinations V, J, D and constant regions, approximately how many antibody combinations are theoretically possible?

Accepted Answer

A)  approximately 10,000 
B)  approximately 1,000,000 
C)  more than 2 million 
D)  more than 1 billion 
A)  approximately 10,000 
B)  approximately 1,000,000 
C)  more than 2 million 
D)  more than 1 billion

Question 4

The structure of epidermal growth factor includes which of the following?

Accepted Answer

A)  four helical segments 
B)  only β-pleated sheet 
C)  both α-helix and β-pleated sheet 
D)  four cysteine residues which form two disulfide bridges 
A)  four helical segments 
B)  only β-pleated sheet 
C)  both α-helix and β-pleated sheet 
D)  four cysteine residues which form two disulfide bridges

Question 5

Which of the following is not a lymphoid organ?

Accepted Answer

A)  spleen 
B)  thymus 
C)  thyroid 
D)  tonsils 
A)  spleen 
B)  thymus 
C)  thyroid 
D)  tonsils

Question 6

Which of the following is true of the Salk vaccine against the polio virus?

Accepted Answer

A)  It contains a virus which has been inactivated by treatment with formaldehyde. 
B)  It contains a mutated form of the virus which is temperature sensitive. 
C)  It contains a very small amount of the natural virus. 
D)  None of the above is correct. 
A)  It contains a virus which has been inactivated by treatment with formaldehyde. 
B)  It contains a mutated form of the virus which is temperature sensitive. 
C)  It contains a very small amount of the natural virus. 
D)  None of the above is correct.

Question 7

The structure of chemotactic cytokines includes which of the following?

Accepted Answer

A)  four helical segments 
B)  only β-pleated sheet 
C)  both α-helix and β-pleated sheet 
D)  four cysteine residues which form two disulfide bridges 
A)  four helical segments 
B)  only β-pleated sheet 
C)  both α-helix and β-pleated sheet 
D)  four cysteine residues which form two disulfide bridges

Question 8

Which of the following is a macrolide drug?

Accepted Answer

A)  cortisol 
B)  cyclosporin A 
C)  interleukin-2 
D)  interferon 
A)  cortisol 
B)  cyclosporin A 
C)  interleukin-2 
D)  interferon

Question 9

Antibodies are which of the following?

Accepted Answer

A)  glycoproteins 
B)  lipoproteins 
C)  macrophages 
D)  T cells 
A)  glycoproteins 
B)  lipoproteins 
C)  macrophages 
D)  T cells

Question 10

Which of the following is true?

Accepted Answer

A)  Both B cells and T cells originate in the bone marrow. 
B)  Both B cells and T cells originate in the thymus. 
C)  Both B cells and T cells mature in the bone marrow. 
D)  Both B cells and T cells mature in the thymus. 
A)  Both B cells and T cells originate in the bone marrow. 
B)  Both B cells and T cells originate in the thymus. 
C)  Both B cells and T cells mature in the bone marrow. 
D)  Both B cells and T cells mature in the thymus.

Question 11

Cytotoxic T cells kill invaders in a manner similar to which of the following?

Accepted Answer

A)  B cells 
B)  dendritic cells 
C)  macrophages 
D)  NK cells 
A)  B cells 
B)  dendritic cells 
C)  macrophages 
D)  NK cells

Question 12

Which of the following is true of immunoglobulins?

Accepted Answer

A)  Only the heavy chains have variable regions. 
B)  Only the light chains have variable regions. 
C)  Both the light and the heavy chains have variable regions. 
D)  Neither the light chains nor the heavy chains have variable regions. 
A)  Only the heavy chains have variable regions. 
B)  Only the light chains have variable regions. 
C)  Both the light and the heavy chains have variable regions. 
D)  Neither the light chains nor the heavy chains have variable regions.

Question 13

Antiviral drugs against HIV have been developed to do which of the following?

Accepted Answer

A)  destroy the virus before it enters a host cell 
B)  inhibit the protease 
C)  both a and b 
D)  neither a nor b 
A)  destroy the virus before it enters a host cell 
B)  inhibit the protease 
C)  both a and b 
D)  neither a nor b

Question 14

Which of the following is true of cytokines?

Accepted Answer

A)  They are glycoproteins. 
B)  They are produced by one cell but alter the function of another. 
C)  both a and b 
D)  neither a nor b 
A)  They are glycoproteins. 
B)  They are produced by one cell but alter the function of another. 
C)  both a and b 
D)  neither a nor b

Question 15

Which of the following hold the chains of an immunoglobulin together?

Accepted Answer

A)  disulfide bridges 
B)  hydrogen bonding 
C)  hydrophobic interactions 
D)  ionic bonds 
A)  disulfide bridges 
B)  hydrogen bonding 
C)  hydrophobic interactions 
D)  ionic bonds

Question 16

Approximately what percentage of invading bacteria and foreign bodies are filtered out in the lymph nodes?

Accepted Answer

A)  50% 
B)  90% 
C)  95% 
D)  99% 
A)  50% 
B)  90% 
C)  95% 
D)  99%

Question 17

The functioning of which of the following explains the rapid mutation of HIV?

Accepted Answer

A)  the way the protease functions 
B)  the way the reverse transcriptase functions 
C)  both a and b 
D)  neither a nor b 
A)  the way the protease functions 
B)  the way the reverse transcriptase functions 
C)  both a and b 
D)  neither a nor b

Question 18

Chemokines are not involved in which of the following?

Accepted Answer

A)  autoimmune disease 
B)  allergic inflammation 
C)  chronic inflammation 
D)  None, they are involved with all of them. 
A)  autoimmune disease 
B)  allergic inflammation 
C)  chronic inflammation 
D)  None, they are involved with all of them.

Question 19

Mutations in the V(J)D genes is called which of the following?

Accepted Answer

A)  affinity maturation 
B)  affinity mutation 
C)  cancer 
D)  none of these 
A)  affinity maturation 
B)  affinity mutation 
C)  cancer 
D)  none of these

Question 20

Mutation of the V(J)D genes in somatic cells results in which of the following?

Accepted Answer

A)  a failure of the immune system 
B)  a decrease in the binding of an antigen to an antibody 
C)  a small increase in the binding of an antigen to an antibody 
D)  a significant increase in the binding of an antigen to an antibody 
A)  a failure of the immune system 
B)  a decrease in the binding of an antigen to an antibody 
C)  a small increase in the binding of an antigen to an antibody 
D)  a significant increase in the binding of an antigen to an antibody

Exam 31: Immunochemistry

Where in a T-cell receptor does binding to the antigen occur?

The enzyme GILT acts on which of the following types of antigens?

Based on all possible combinations V, J, D and constant regions, approximately how many antibody combinations are theoretically possible?

The structure of epidermal growth factor includes which of the following?

Which of the following is not a lymphoid organ?

Which of the following is true of the Salk vaccine against the polio virus?

The structure of chemotactic cytokines includes which of the following?

Which of the following is a macrolide drug?

Antibodies are which of the following?

Which of the following is true?

Cytotoxic T cells kill invaders in a manner similar to which of the following?

Which of the following is true of immunoglobulins?

Antiviral drugs against HIV have been developed to do which of the following?

Which of the following is true of cytokines?

Which of the following hold the chains of an immunoglobulin together?

Approximately what percentage of invading bacteria and foreign bodies are filtered out in the lymph nodes?

The functioning of which of the following explains the rapid mutation of HIV?

Chemokines are not involved in which of the following?

Mutations in the V(J)D genes is called which of the following?

Mutation of the V(J)D genes in somatic cells results in which of the following?

Matter, Energy, and Measurement

Atoms

Chemical Bonds

Chemical Reactions

Gases, Liquids, and Solids

Solutions and Colloids

Reaction Rates and Chemical Equilibrium

Acids and Bases

Nuclear Chemistry

Organic Chemistry

Alkanes

Alkenes and Alkynes

Benzene and Its Derivatives

Alcohols, Ethers, and Thiols

Chirality: the Handedness of Molecules

Amines

Aldehydes and Ketones

Carboxylic Acids

Carboxylic Anhydrides, Esters, and Amides

Carbohydrates

Lipids

Proteins

Enzymes

Chemical Communications: Neurotransmitters and Hormones

Nucleotides, Nucleic Acids, and Heredity

Gene Expression and Protein Synthesis

Bioenergetics: How the Body Converts Food to Energy

Specific Catabolic Pathways: Carbohydrate, Lipid, and Protein Metabolism

Biosynthetic Pathways

Nutrition

Body Fluids

Filters