Question 1

Point mutations include which of the following?

Accepted Answer

A)  Substitutions 
B)  Insertions 
C)  Deletions 
D)  Substitutions, insertions, and deletions 
A)  Substitutions 
B)  Insertions 
C)  Deletions 
D)  Substitutions, insertions, and deletions

Question 2

When an individual is said to have blood group A, it refers to the individual's:

Accepted Answer

A)  alleles on the chromosome. 
B)  genotype. 
C)  phenotype. 
D)  haplotype. 
A)  alleles on the chromosome. 
B)  genotype. 
C)  phenotype. 
D)  haplotype.

Question 3

What amino acid initiates translation by attaching to tRNA?

Accepted Answer

A)  Glycine 
B)  Alanine 
C)  Methionine 
D)  Lysine 
A)  Glycine 
B)  Alanine 
C)  Methionine 
D)  Lysine

Question 4

Methods to isolate intact DNA in order for it to be studied include all of the following except:

Accepted Answer

A)  pH changes. 
B)  enzyme activation. 
C)  detergent lysis. 
D)  heat treatment. 
A)  pH changes. 
B)  enzyme activation. 
C)  detergent lysis. 
D)  heat treatment.

Question 5

What blood group is the best example of codominantly inherited blood group genes?

Accepted Answer

A)  Rh 
B)  MN 
C)  Lewis 
D)  ABO 
A)  Rh 
B)  MN 
C)  Lewis 
D)  ABO

Question 6

A structural alteration of DNA in an organism that is caused by a physical or chemical agent is called:

Accepted Answer

A)  transcription. 
B)  translation. 
C)  mutation. 
D)  cloning. 
A)  transcription. 
B)  translation. 
C)  mutation. 
D)  cloning.

Question 7

The diploid chromosome number in humans is:

Accepted Answer

A)  12 
B)  23 
C)  46 
D)  92 
A)  12 
B)  23 
C)  46 
D)  92

Question 8

All of the following processes occur in replication, except:

Accepted Answer

A)  the two DNA strands separate via helicase. 
B)  DNA polymerase acts on the 5' to 3' parent strand to produce an anticomplementary duplicate strand. 
C)  DNA polymerase acts on the 3' to 5' parent strand to produce an anticomplementary duplicate strand. 
D)  replication of the 3' to 5' parent strand is initiated by the enzyme primase, which anneals to the parent strand. 
A)  the two DNA strands separate via helicase. 
B)  DNA polymerase acts on the 5' to 3' parent strand to produce an anticomplementary duplicate strand. 
C)  DNA polymerase acts on the 3' to 5' parent strand to produce an anticomplementary duplicate strand. 
D)  replication of the 3' to 5' parent strand is initiated by the enzyme primase, which anneals to the parent strand.

Question 9

Alternate forms of a gene that can occur at a single chromosome locus are referred to as:

Accepted Answer

A)  amorphs. 
B)  traits. 
C)  alleles. 
D)  recessive. 
A)  amorphs. 
B)  traits. 
C)  alleles. 
D)  recessive.

Question 10

What is meant by the term autosomal?

Accepted Answer

A)  Trait is not carried on the sex chromosomes 
B)  Trait is carried on sex chromosomes 
C)  Trait is not expressed in the parents 
D)  Organism possesses different alleles for a given characteristic 
A)  Trait is not carried on the sex chromosomes 
B)  Trait is carried on sex chromosomes 
C)  Trait is not expressed in the parents 
D)  Organism possesses different alleles for a given characteristic

Question 11

The two strands of DNA are: ; one runs in a 5' to 3' direction, and the other runs in a 3' to 5' direction.

Accepted Answer

A)  parallel 
B)  antiparallel 
C)  somatic 
D)  zigzag 
A)  parallel 
B)  antiparallel 
C)  somatic 
D)  zigzag

Question 12

All of the following are included in transcription except:

Accepted Answer

A)  mRNA terminates at the 5' end. 
B)  RNA polymerase II binds to a promoter. 
C)  it proceeds from the 3' end to the 5' end. 
D)  the 5' end is capped with a methyl residue. 
A)  mRNA terminates at the 5' end. 
B)  RNA polymerase II binds to a promoter. 
C)  it proceeds from the 3' end to the 5' end. 
D)  the 5' end is capped with a methyl residue.

Question 13

All of the following may cause an alteration in DNA, except:

Accepted Answer

A)  ultraviolet light. 
B)  alkylating agents. 
C)  antibodies. 
D)  enzymes. 
A)  ultraviolet light. 
B)  alkylating agents. 
C)  antibodies. 
D)  enzymes.

Question 14

Using the Hardy-Weinberg equation, if a total random population carried the dominant allele E and 20% carried the recessive allele e, what would the total percentage be for the recessive trait ee?

Accepted Answer

A)  64% 
B)  4% 
C)  16% 
D)  0.4% 
A)  64% 
B)  4% 
C)  16% 
D)  0.4%

Question 15

When 1,000 donors were tested, 75% were positive for C and 25% were negative for C; the gene frequency of C is:

Accepted Answer

A) 10. 
B) 1. 
C)  0.5. 
D)  25. 
A) 10. 
B) 1. 
C)  0.5. 
D)  25.

Question 16

How is RNA different from DNA?

Accepted Answer

A)  RNA usually exists as one strand 
B)  Ribose is substituted for deoxyribose 
C)  RNA incorporates uracil 
D)  All of the above 
A)  RNA usually exists as one strand 
B)  Ribose is substituted for deoxyribose 
C)  RNA incorporates uracil 
D)  All of the above

Question 17

In what stage of mitosis is DNA not actively dividing?

Accepted Answer

A)  Interphase 
B)  Prophase 
C)  Metaphase 
D)  Anaphase 
A)  Interphase 
B)  Prophase 
C)  Metaphase 
D)  Anaphase

Question 18

In which of the following circumstances will Hardy-Weinberg's principle fail?

Accepted Answer

A)  Mutation 
B)  Genetic drift 
C)  Non-random mating 
D)  All the above 
A)  Mutation 
B)  Genetic drift 
C)  Non-random mating 
D)  All the above

Question 19

DNA is composed of all of the following except:

Accepted Answer

A)  adenine. 
B)  guanine. 
C)  cytosine. 
D)  uracil. 
A)  adenine. 
B)  guanine. 
C)  cytosine. 
D)  uracil.

Question 20

Most antigens in the various blood group systems follow what kind of inheritance patterns?

Accepted Answer

A)  Codominant 
B)  Homozygous 
C)  Dominant 
D)  Autosomal 
A)  Codominant 
B)  Homozygous 
C)  Dominant 
D)  Autosomal

Exam 2: Basic Genetics

Point mutations include which of the following?

When an individual is said to have blood group A, it refers to the individual's:

What amino acid initiates translation by attaching to tRNA?

Methods to isolate intact DNA in order for it to be studied include all of the following except:

What blood group is the best example of codominantly inherited blood group genes?

A structural alteration of DNA in an organism that is caused by a physical or chemical agent is called:

The diploid chromosome number in humans is:

All of the following processes occur in replication, except:

Alternate forms of a gene that can occur at a single chromosome locus are referred to as:

What is meant by the term autosomal?

The two strands of DNA are: ; one runs in a 5' to 3' direction, and the other runs in a 3' to 5' direction.

All of the following are included in transcription except:

All of the following may cause an alteration in DNA, except:

Using the Hardy-Weinberg equation, if a total random population carried the dominant allele E and 20% carried the recessive allele e, what would the total percentage be for the recessive trait ee?

When 1,000 donors were tested, 75% were positive for C and 25% were negative for C; the gene frequency of C is:

How is RNA different from DNA?

In what stage of mitosis is DNA not actively dividing?

In which of the following circumstances will Hardy-Weinberg's principle fail?

DNA is composed of all of the following except:

Most antigens in the various blood group systems follow what kind of inheritance patterns?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Blood Group Terminology and the Other Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Transfusion Therapy

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

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