Question 1

Prosthetic joint infection is most often because of

Accepted Answer

A)  defective replacement material. 
B)  injury to the joint. 
C)  hematogenous transfer. 
D)  arthritis. 
A)  defective replacement material. 
B)  injury to the joint. 
C)  hematogenous transfer. 
D)  arthritis. C

Question 2

Enteropathic arthritis is associated with

Accepted Answer

A)  irritable bowel syndrome. 
B)  inflammatory bowel disease. 
C)  chronic constipation. 
D)  chronic diarrhea. 
A)  irritable bowel syndrome. 
B)  inflammatory bowel disease. 
C)  chronic constipation. 
D)  chronic diarrhea. B

Question 3

Rheumatoid arthritis involves joint inflammation caused by

Accepted Answer

A)  bacterial infection. 
B)  trauma. 
C)  autoimmune injury. 
D)  congenital hypermobility. 
A)  bacterial infection. 
B)  trauma. 
C)  autoimmune injury. 
D)  congenital hypermobility. C

Question 4

Tophi are

Accepted Answer

A)  renal calculi composed of uric acid. 
B)  deposits of urate crystals in tissues. 
C)  painful edematous joints. 
D)  spots that coalesce in a malar rash. 
A)  renal calculi composed of uric acid. 
B)  deposits of urate crystals in tissues. 
C)  painful edematous joints. 
D)  spots that coalesce in a malar rash.

Question 5

Rheumatoid arthritis is commonly associated with the presence of rheumatoid factor autoantibodies in the bloodstream.This indicates that rheumatoid arthritis is likely to be

Accepted Answer

A)  caused by bacterial infection. 
B)  an autoimmune process. 
C)  an infective process. 
D)  because of an enzymatic defect. 
A)  caused by bacterial infection. 
B)  an autoimmune process. 
C)  an infective process. 
D)  because of an enzymatic defect.

Question 6

The most common presenting sign/symptom with rheumatic fever is

Accepted Answer

A)  cardiac murmur. 
B)  polyarthritis. 
C)  rash. 
D)  painless nodules. 
A)  cardiac murmur. 
B)  polyarthritis. 
C)  rash. 
D)  painless nodules.

Question 7

Characteristics of gout include (Select all that apply.)

Accepted Answer

A)  disturbed uric acid metabolism. 
B)  crystalline deposits in bony and connective tissue. 
C)  onset before menopause in women. 
D)  cardiac involvement. 
E)  renal involvement. 
A)  disturbed uric acid metabolism. 
B)  crystalline deposits in bony and connective tissue. 
C)  onset before menopause in women. 
D)  cardiac involvement. 
E)  renal involvement.

Question 8

Ankylosing spondylitis causes

Accepted Answer

A)  intervertebral joint fusion. 
B)  instability of synovial joints. 
C)  costal cartilage degeneration. 
D)  temporomandibular joint degeneration. 
A)  intervertebral joint fusion. 
B)  instability of synovial joints. 
C)  costal cartilage degeneration. 
D)  temporomandibular joint degeneration.

Question 9

Although skin manifestations may occur in numerous locations,the classic presentation of systemic lupus erythematosus (SLE)includes

Accepted Answer

A)  lesions affecting the palms of hands and the soles of feet. 
B)  dry, scaly patches in the antecubital area and behind the knees. 
C)  cracked, scaly areas in the webs of fingers. 
D)  a butterfly pattern rash on the face across the bridge of the nose. 
A)  lesions affecting the palms of hands and the soles of feet. 
B)  dry, scaly patches in the antecubital area and behind the knees. 
C)  cracked, scaly areas in the webs of fingers. 
D)  a butterfly pattern rash on the face across the bridge of the nose.

Question 10

The final stage of gout,characterized by crystalline deposits in cartilage,synovial membranes,and soft tissue,is called

Accepted Answer

A)  tophaceous gout. 
B)  gouty arthritis. 
C)  complicated gout. 
D)  asymptomatic hyperuricemia. 
A)  tophaceous gout. 
B)  gouty arthritis. 
C)  complicated gout. 
D)  asymptomatic hyperuricemia.

Question 11

Individuals diagnosed with systemic lupus erythematosus (SLE)are at risk for developing numerous complications of various organs because of

Accepted Answer

A)  excessive production of connective tissue. 
B)  formation of osteophytes in tissues. 
C)  immune injury to basement membranes. 
D)  impaired tissue oxygen transport. 
A)  excessive production of connective tissue. 
B)  formation of osteophytes in tissues. 
C)  immune injury to basement membranes. 
D)  impaired tissue oxygen transport.

Question 12

It is true that scleroderma involves

Accepted Answer

A)  inflammation and fibrosis of connective tissue. 
B)  autoantibodies against acetylcholine receptors. 
C)  infection by beta-hemolytic streptococcus. 
D)  inflammation caused by antigenic fragments of dead organisms. 
A)  inflammation and fibrosis of connective tissue. 
B)  autoantibodies against acetylcholine receptors. 
C)  infection by beta-hemolytic streptococcus. 
D)  inflammation caused by antigenic fragments of dead organisms.

Question 13

"Please explain the pathophysiology of osteoarthritis to me," says another nurse."Is it just wear and tear so that the cartilage wears out?" Your best response is

Accepted Answer

A)  "Yes; repeated use just wears out the cartilage, until it becomes thin and denuded. That causes pain and will eventually cause joint inflammation." 
B)  "Yes; with increasing age, the inflammation from repeated joint use accumulates and causes the cartilage to get thin and ragged until it disappears." 
C)  "No; cells in bone, cartilage, and the synovial membrane all get activated and secrete inflammatory mediators that destroy cartilage and damage bone." 
D)  "No; autoimmune cells infiltrate the joint and collect on the cartilage in a mass called 'pannus' that eventually thins and destroys the cartilage." 
A)  "Yes; repeated use just wears out the cartilage, until it becomes thin and denuded. That causes pain and will eventually cause joint inflammation." 
B)  "Yes; with increasing age, the inflammation from repeated joint use accumulates and causes the cartilage to get thin and ragged until it disappears." 
C)  "No; cells in bone, cartilage, and the synovial membrane all get activated and secrete inflammatory mediators that destroy cartilage and damage bone." 
D)  "No; autoimmune cells infiltrate the joint and collect on the cartilage in a mass called 'pannus' that eventually thins and destroys the cartilage."

Question 14

Signs/symptoms of Lyme disease include (Select all that apply.)

Accepted Answer

A)  fever and chills. 
B)  migratory rash. 
C)  arthritic pain. 
D)  headache. 
E)  myalgia. 
A)  fever and chills. 
B)  migratory rash. 
C)  arthritic pain. 
D)  headache. 
E)  myalgia.

Question 15

Systemic lupus erythematosus (SLE)is a rheumatic disease attributed to

Accepted Answer

A)  wear and tear on weight-bearing joints. 
B)  septic joint inflammation and necrosis. 
C)  unknown etiologic factors. 
D)  autoimmune mechanisms. 
A)  wear and tear on weight-bearing joints. 
B)  septic joint inflammation and necrosis. 
C)  unknown etiologic factors. 
D)  autoimmune mechanisms.

Question 16

Gouty arthritis is a complication of

Accepted Answer

A)  group A streptococcal infection. 
B)  autoimmune destruction of joint collagen. 
C)  excessive production of urea. 
D)  inadequate renal excretion of uric acid. 
A)  group A streptococcal infection. 
B)  autoimmune destruction of joint collagen. 
C)  excessive production of urea. 
D)  inadequate renal excretion of uric acid.

Question 17

Systemic disorders include

Accepted Answer

A)  adhesive capsulitis. 
B)  verrucae. 
C)  osteoarthritis. 
D)  rheumatoid arthritis. 
A)  adhesive capsulitis. 
B)  verrucae. 
C)  osteoarthritis. 
D)  rheumatoid arthritis.

Question 18

A laboratory test result that helps confirm the diagnosis of systemic lupus erythematosus (SLE)is

Accepted Answer

A)  elevated serum calcium level. 
B)  elevated monoclonal antibody titer. 
C)  positive antinuclear antibodies. 
D)  positive microsomal antibodies. 
A)  elevated serum calcium level. 
B)  elevated monoclonal antibody titer. 
C)  positive antinuclear antibodies. 
D)  positive microsomal antibodies.

Question 19

Ankylosing spondylitis is characterized by

Accepted Answer

A)  inflammation, stiffness, and fusion of spinal joints. 
B)  loss of articular cartilage in weight-bearing joints. 
C)  excessive bone remodeling leading to soft bone. 
D)  immune mechanisms leading to widespread joint inflammation. 
A)  inflammation, stiffness, and fusion of spinal joints. 
B)  loss of articular cartilage in weight-bearing joints. 
C)  excessive bone remodeling leading to soft bone. 
D)  immune mechanisms leading to widespread joint inflammation.

Question 20

Manifestations of osteoarthritis include (Select all that apply.)

Accepted Answer

A)  nodules on joints of the hands. 
B)  crepitus with joint movement. 
C)  pain that is worse upon arising in the morning. 
D)  stiffness that worsens with joint use. 
E)  narrowing of joint spaces. 
A)  nodules on joints of the hands. 
B)  crepitus with joint movement. 
C)  pain that is worse upon arising in the morning. 
D)  stiffness that worsens with joint use. 
E)  narrowing of joint spaces.

Exam 52: Alterations in Musculoskeletal Function: Rheumatic Disorders

Prosthetic joint infection is most often because of

Enteropathic arthritis is associated with

Rheumatoid arthritis involves joint inflammation caused by

Tophi are

Rheumatoid arthritis is commonly associated with the presence of rheumatoid factor autoantibodies in the bloodstream.This indicates that rheumatoid arthritis is likely to be

The most common presenting sign/symptom with rheumatic fever is

Characteristics of gout include (Select all that apply.)

Ankylosing spondylitis causes

Although skin manifestations may occur in numerous locations,the classic presentation of systemic lupus erythematosus (SLE)includes

The final stage of gout,characterized by crystalline deposits in cartilage,synovial membranes,and soft tissue,is called

Individuals diagnosed with systemic lupus erythematosus (SLE)are at risk for developing numerous complications of various organs because of

It is true that scleroderma involves

"Please explain the pathophysiology of osteoarthritis to me," says another nurse."Is it just wear and tear so that the cartilage wears out?" Your best response is

Signs/symptoms of Lyme disease include (Select all that apply.)

Systemic lupus erythematosus (SLE)is a rheumatic disease attributed to

Gouty arthritis is a complication of

Systemic disorders include

A laboratory test result that helps confirm the diagnosis of systemic lupus erythematosus (SLE)is

Ankylosing spondylitis is characterized by

Manifestations of osteoarthritis include (Select all that apply.)

Introduction to Pathophysiology

Homeostasis, Allostasis, and Adaptive Responses to Stressors

Cell Structure and Function

Cell Injury, Aging, and Death

Genome Structure, Regulation, and Tissue Differentiation

Genetic and Developmental Disorders

Neoplasia

Infectious Processes

Inflammation and Immunity

Alterations in Immune Function

Malignant Disorders of White Blood Cells

HIV Disease and Aids

Alterations in Oxygen Transport

Alterations in Homeostasis and Blood Coagulation

Alterations in Blood Flow

Alterations in Blood Pressure

Cardiac Function

Alterations in Cardiac Function

Heart Failure and Dysrhythmias: Common Sequelae of Cardiac Diseases

Shock

Respiratory Function and Alterations in Gas Exchange

Obstructive Pulmonary Disorders

Restrictive Pulmonary Disorders

Fluid and Electrolyte Homeostasis and Imbalances

Acid-Base Homeostasis and Imbalances

Renal Function

Intrarenal Disorders

Acute Kidney Injury and Chronic Kidney Disease

Disorders of the Lower Urinary Tract

Male Genital and Reproductive Function

Alterations in Male Genital and Reproductive Function

Female Genital and Reproductive Function

Alterations in Female Genital and Reproductive Function

Sexually Transmitted Infections

Gastrointestinal Function

Gastrointestinal Disorders

Alterations in Function of the Gallbladder and Exocrine Pancreas

Liver Diseases

Endocrine Physiology and Mechanisms of Hypothalamic-Pituitary Regulation

Disorders of Endocrine Function

Diabetes Mellitus

Alterations in Metabolism and Nutrition

Structure and Function of the Nervous System

Acute Disorders of Brain Function

Chronic Disorders of Neurologic Function

Alterations in Special Sensory Function

Pain

Neurobiology of Psychotic Illnesses

Neurobiology of Nonpsychotic Illnesses

Structure and Function of the Musculoskeletal System

Alterations in Musculoskeletal Function: Trauma, Infection, and Disease

Alterations in the Integumentary System

Burn Injuries

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