Question 1

The coenzyme _____ is the oxidizing agent in glycolysis.

Accepted Answer

A)  ADP 
B)  thiamine pyrophosphate 
C)  NAD+ 
D)  FAD 
E)  biotin 
A)  ADP 
B)  thiamine pyrophosphate 
C)  NAD+ 
D)  FAD 
E)  biotin

Question 2

Which of the following statements about glycogen is true?
I. Glycogen is a polymer of glucose in  $\alpha$ (1  $\rarr$ 6) linkages with  $\alpha$ (1  $\rarr$ 4) linked branches every 8-14 residues.
II. UDP-glucose is produced from glycogen by the action of the enzyme phosphorylase.
III. In glycogen breakdown, glucose residues are sequentially removed from the nonreducing ends.
IV. The breakdown of glycogen in skeletal muscle ultimately supplies glucose-6-phosphate, which can enter glycolysis to generate ATP.

Accepted Answer

A)  I, II, III, IV 
B)  I, II 
C)  II, III, IV 
D)  III, IV 
E)  III only 
A)  I, II, III, IV 
B)  I, II 
C)  II, III, IV 
D)  III, IV 
E)  III only

Question 3

During infancy, an inability to convert ___ into glucose can be deadly since ___ is the major carbohydrate source.

Accepted Answer

The answer of During infancy, an inability to convert ___...

Question 4

Which of the following represents the net products of glycolysis from one molecule of glucose?

Accepted Answer

A)  2 pyruvate, 2 NADH, 2 ATP 
B)  2 pyruvate, 2 NADH, 4 ATP 
C)  3 pyruvate, 2 NADH, 4 ATP 
D)  6 CO2, 30 ATP 
E)  6 CO2, 32 ATP 
A)  2 pyruvate, 2 NADH, 2 ATP 
B)  2 pyruvate, 2 NADH, 4 ATP 
C)  3 pyruvate, 2 NADH, 4 ATP 
D)  6 CO2, 30 ATP 
E)  6 CO2, 32 ATP

Question 5

Which of the following correctly relates the order of intermediates during the synthesis of glycogen?

Accepted Answer

A)  glucose  $\rarr$  glucose-1-phosphate  $\rarr$ glucose-6-phosphate  $\rarr$ UDP-glucose  $\rarr$  glycogen 
B)  glucose  $\rarr$  glucose-6-phosphate  $\rarr$  glucose-1-phosphate  $\rarr$  UDP-glucose  $\rarr$  glycogen 
C)  glucose  $\rarr$ glucose-6-phosphate  $\rarr$  UDP-glucose  $\rarr$ glucose-1-phosphate  $\rarr$ glycogen 
D)  glucose  $\rarr$ UDP-glucose  $\rarr$  glucose-1-phosphate  $\rarr$  glucose-6-phosphate $\rarr$  glycogen 
E)  glucose  $\rarr$  UDP-glucose  $\rarr$  glucose-6-phosphate  $\rarr$ glucose-1-phosphate  $\rarr$  glycogen 
A)  glucose  $\rarr$  glucose-1-phosphate  $\rarr$ glucose-6-phosphate  $\rarr$ UDP-glucose  $\rarr$  glycogen 
B)  glucose  $\rarr$  glucose-6-phosphate  $\rarr$  glucose-1-phosphate  $\rarr$  UDP-glucose  $\rarr$  glycogen 
C)  glucose  $\rarr$ glucose-6-phosphate  $\rarr$  UDP-glucose  $\rarr$ glucose-1-phosphate  $\rarr$ glycogen 
D)  glucose  $\rarr$ UDP-glucose  $\rarr$  glucose-1-phosphate  $\rarr$  glucose-6-phosphate $\rarr$  glycogen 
E)  glucose  $\rarr$  UDP-glucose  $\rarr$  glucose-6-phosphate  $\rarr$ glucose-1-phosphate  $\rarr$  glycogen

Question 6

Which is the net equation for aerobic glycolysis?

Accepted Answer

A)  Glucose + 2 ATP  $\rarr$ 2 lactate + 2 ADP + 2 Pi 
B)  Glucose + 2 ADP + 2 Pi + 2 NAD+  $\rarr$  2 pyruvate + 2 ATP + 2 NADH + + 2 H2O 4 H+ 
C)  Glucose + 2 ADP + 2 Pi  $\rarr$  2 lactate + 4 ATP + 4 H+ 
D)  Glucose + 2 ATP + 2 NAD+ $\rarr$  2 pyruvate + 4 ATP + 4 NADH + 4 H+ 
E)  Glucose + 2 ADP + 2 Pi + 2 NAD+ $\rarr$  2 lactate + 4 ATP + 2 NADH + 4 H+ 
A)  Glucose + 2 ATP  $\rarr$ 2 lactate + 2 ADP + 2 Pi 
B)  Glucose + 2 ADP + 2 Pi + 2 NAD+  $\rarr$  2 pyruvate + 2 ATP + 2 NADH + + 2 H2O 4 H+ 
C)  Glucose + 2 ADP + 2 Pi  $\rarr$  2 lactate + 4 ATP + 4 H+ 
D)  Glucose + 2 ATP + 2 NAD+ $\rarr$  2 pyruvate + 4 ATP + 4 NADH + 4 H+ 
E)  Glucose + 2 ADP + 2 Pi + 2 NAD+ $\rarr$  2 lactate + 4 ATP + 2 NADH + 4 H+

Question 7

In the event that NADPH is needed but ribose is not, which of the following is an end product of the pentose phosphate pathway?

Accepted Answer

A)  ribulose-5-phosphate 
B)  dihydroxyacetone phosphate 
C)  fructose-1,6-bisphosphate 
D)  1,3-bisphosphoglycerate 
E)  glyceraldehyde-3-phosphate 
A)  ribulose-5-phosphate 
B)  dihydroxyacetone phosphate 
C)  fructose-1,6-bisphosphate 
D)  1,3-bisphosphoglycerate 
E)  glyceraldehyde-3-phosphate

Question 8

Phosphoglucose isomerase has a  $\Delta$ G        of 2.2 kJ/mol but a  $\Delta$ G of -1.4 kJ/mol. Based upon this difference, which of the following is true?

Accepted Answer

A)  within a cell, concentrations are non-standard 
B)  within a cell, the concentration of glucose-6-phosphate is higher than fructose-6-phosphate 
C)  within a cell, concentrations of products are often lowered by their rapid use in other reactions 
D)  within a cell, the reaction catalyzed by phosphoglucose isomerase would be considered freely reversible 
E)  all of the above 
A)  within a cell, concentrations are non-standard 
B)  within a cell, the concentration of glucose-6-phosphate is higher than fructose-6-phosphate 
C)  within a cell, concentrations of products are often lowered by their rapid use in other reactions 
D)  within a cell, the reaction catalyzed by phosphoglucose isomerase would be considered freely reversible 
E)  all of the above

Question 9

Fill in the missing reagents in the following reaction.

Accepted Answer

A)  reactant: NAD+ + H+; product: NADH 
B)  reactant: NADH + H+; product: NAD+ 
C)  reactant: ATP; product: ADP + Pi 
D)  reactant: NADH + H+; product: CO2 
E)  none of the above 
A)  reactant: NAD+ + H+; product: NADH 
B)  reactant: NADH + H+; product: NAD+ 
C)  reactant: ATP; product: ADP + Pi 
D)  reactant: NADH + H+; product: CO2 
E)  none of the above

Question 10

Which of the following best describes the function of the glycogen debranching enzyme in glycogenolysis?

Accepted Answer

A)  It cleaves  $\alpha$ (1  $\rarr$  6) branch points releasing glucose-6-phosphate. 
B)  It cleaves  $\alpha$ (1  $\rarr$  6) branch points releasing glucose-1-phosphate. 
C)  It cleaves  $\alpha$ (1  $\rarr$  6) branch points releasing glucose. 
D)  It transfers an  $\alpha$ (1  $\rarr$ 4) linked trisaccharide unit to the nonreducing end of an alternate branch, then cleaves the  $\alpha$ (1  $\rarr$  6) branch point, releasing glucose-1-phosphate. 
E)  It transfers an  $\alpha$ (1  $\rarr$  4) linked trisaccharide to the nonreducing end of an alternate branch, then cleaves the  $\alpha$ (1 $\rarr$  6) branch point, releasing glucose. 
A)  It cleaves  $\alpha$ (1  $\rarr$  6) branch points releasing glucose-6-phosphate. 
B)  It cleaves  $\alpha$ (1  $\rarr$  6) branch points releasing glucose-1-phosphate. 
C)  It cleaves  $\alpha$ (1  $\rarr$  6) branch points releasing glucose. 
D)  It transfers an  $\alpha$ (1  $\rarr$ 4) linked trisaccharide unit to the nonreducing end of an alternate branch, then cleaves the  $\alpha$ (1  $\rarr$  6) branch point, releasing glucose-1-phosphate. 
E)  It transfers an  $\alpha$ (1  $\rarr$  4) linked trisaccharide to the nonreducing end of an alternate branch, then cleaves the  $\alpha$ (1 $\rarr$  6) branch point, releasing glucose.

Question 11

The enzyme responsible for the synthesis of fructose-2,6-bisphosphate is _____.

Accepted Answer

A)  phosphofructokinase-2 
B)  hexosephosphatekinase-2 
C)  aldolase-2 
D)  phosphofructose isomerase-2 
E)  none of the above 
A)  phosphofructokinase-2 
B)  hexosephosphatekinase-2 
C)  aldolase-2 
D)  phosphofructose isomerase-2 
E)  none of the above

The coenzyme _____ is the oxidizing agent in glycolysis.

During infancy, an inability to convert _ into glucose can be deadly since _ is the major carbohydrate source.

Which of the following represents the net products of glycolysis from one molecule of glucose?

Which of the following correctly relates the order of intermediates during the synthesis of glycogen?

Which is the net equation for aerobic glycolysis?

In the event that NADPH is needed but ribose is not, which of the following is an end product of the pentose phosphate pathway?

Fill in the missing reagents in the following reaction.

Which of the following best describes the function of the glycogen debranching enzyme in glycogenolysis?

The enzyme responsible for the synthesis of fructose-2,6-bisphosphate is _____.

The Chemical Basis of Life

Aqueous Chemistry

Nucleic Acid Structure and Function

Protein Structure

Protein Function

How Enzymes Work

Enzyme Kinetics and Inhibition

Lipids and Membranes

Membrane Transport

Signaling

Carbohydrates

Metabolism and Bioenergetics

The Citric Acid Cycle

Oxidative Phosphorylation

Photosynthesis

Lipid Metabolism

Nitrogen Metabolism

Regulation of Mammalian Fuel Metabolism

DNA Replication and Repair

Transcription and RNA

Protein Synthesis

Filters

Exam 13: Glucose Metabolism

The coenzyme _____ is the oxidizing agent in glycolysis.

During infancy, an inability to convert ___ into glucose can be deadly since ___ is the major carbohydrate source.

Which of the following represents the net products of glycolysis from one molecule of glucose?

Which of the following correctly relates the order of intermediates during the synthesis of glycogen?

Which is the net equation for aerobic glycolysis?

In the event that NADPH is needed but ribose is not, which of the following is an end product of the pentose phosphate pathway?

Phosphoglucose isomerase has a Δ\DeltaΔ G of 2.2 kJ/mol but a Δ\DeltaΔ G of -1.4 kJ/mol. Based upon this difference, which of the following is true?

Fill in the missing reagents in the following reaction.

Which of the following best describes the function of the glycogen debranching enzyme in glycogenolysis?

The enzyme responsible for the synthesis of fructose-2,6-bisphosphate is _____.

The Chemical Basis of Life

Aqueous Chemistry

Nucleic Acid Structure and Function

Protein Structure

Protein Function

How Enzymes Work

Enzyme Kinetics and Inhibition

Lipids and Membranes

Membrane Transport

Signaling

Carbohydrates

Metabolism and Bioenergetics

The Citric Acid Cycle

Oxidative Phosphorylation

Photosynthesis

Lipid Metabolism

Nitrogen Metabolism

Regulation of Mammalian Fuel Metabolism

DNA Replication and Repair

Transcription and RNA

Protein Synthesis

Filters

During infancy, an inability to convert _ into glucose can be deadly since _ is the major carbohydrate source.