Question 1

Where is 5S rRNA synthesized?

Accepted Answer

On a chromosome outs

Question 2

Chromatin domains appear to represent discrete functional units that independently regulate gene expression.

Accepted Answer

A) True 
 B)False

Question 3

Which of the following is not involved in the transport of RNAs out of the nucleus?

Accepted Answer

A)  Ran 
B)  Expenditure of chemical energy 
C)  Small RNAs crossing by passive diffusion 
D)  Exportins 
A)  Ran 
B)  Expenditure of chemical energy 
C)  Small RNAs crossing by passive diffusion 
D)  Exportins

Question 4

How many copies of the large ribosomal RNA gene does the human genome contain?

Accepted Answer

The answer of How many copies of the large ribosomal...

Question 5

Protein transport into the endoplasmic reticulum (ER) or mitochondria requires unfolding of the protein and threading the amino acid chain through a channel or pore into the organelle. In contrast, protein transport into the nucleus does not require unfolding of the protein. Why is unfolding unnecessary for nuclear protein import?

Accepted Answer

The nuclear pore complex is a huge struc

Question 6

Polycomb proteins promote heterochromatin formation and gene silencing by

Accepted Answer

A)  acetylating lysine 27 of histone 3. 
B)  deacetylating lysine 27 of histone 3. 
C)  methylating lysine 27 of histone 3. 
D)  methylating lysine 9 of histone 3. 
A)  acetylating lysine 27 of histone 3. 
B)  deacetylating lysine 27 of histone 3. 
C)  methylating lysine 27 of histone 3. 
D)  methylating lysine 9 of histone 3.

Question 7

The nucleolus is the site of rRNA synthesis and processing and of ribosomal subunit assembly.

Accepted Answer

A) True 
 B)False

Question 8

Give one example of how regulation of nuclear protein import is involved in gene regulation.

Accepted Answer

Some transcription factors that act on n

Question 9

Within the nucleolus, what functions are associated with the fibrillar center, dense fibrillar component, and granular component?

Accepted Answer

The fibrillar center is the si

Question 10

By restricting the traffic of proteins and RNA across the nuclear envelope, eukaryotic cells can regulate _______ in unique ways.

Accepted Answer

A)  translation and transcription 
B)  transcription only 
C)  translation only 
D)  endocytosis 
A)  translation and transcription 
B)  transcription only 
C)  translation only 
D)  endocytosis

Question 11

Which of the following is an example of nucleolar involvement in processing of non-rRNAs?

Accepted Answer

A)  Base modification within tRNAs catalyzed by snoRNPs 
B)  Storage of pre-mRNA splicing factors 
C)  Gene silencing 
D)  Proteasomal proteolysis 
A)  Base modification within tRNAs catalyzed by snoRNPs 
B)  Storage of pre-mRNA splicing factors 
C)  Gene silencing 
D)  Proteasomal proteolysis

Question 12

Transcriptionally active chromatin, which is called _______, is decondensed, while transcriptionally inactive chromatin, which is called _______, is highly condensed.

Accepted Answer

euchromati

Question 13

What are nuclear speckles?

Accepted Answer

Nuclear speckles are

Question 14

Most snoRNAs

Accepted Answer

A)  splice cleaved mRNAs. 
B)  splice cleaved rRNAs. 
C)  cleave the 45S rRNA. 
D)  guide regions of rRNAs to modifying enzymes. 
A)  splice cleaved mRNAs. 
B)  splice cleaved rRNAs. 
C)  cleave the 45S rRNA. 
D)  guide regions of rRNAs to modifying enzymes.

Question 15

Proteins called _______ act as receptors for cargo protein import into the nucleus, and proteins called _______ play the corresponding role in export from the nucleus.

Accepted Answer

importins;

Question 16

Which of the following are not compartments in the nucleus?

Accepted Answer

A)  Clustered DNA replication sites 
B)  Lipid droplets 
C)  PML bodies 
D)  Speckles enriched in RNA splicing components 
A)  Clustered DNA replication sites 
B)  Lipid droplets 
C)  PML bodies 
D)  Speckles enriched in RNA splicing components

Question 17

The nuclear localization signal (NLS) is not removed (cleaved off) after entry of the protein into the nucleus. In contrast, the targeting sequences of proteins destined for organelles such as the mitochondria are located at the N-terminus of the protein and are cleaved off once the proteins reach the lumen of the organelle. What are two likely reasons that the nuclear localization signal (NLS) is not cleaved off for nuclear proteins?

Accepted Answer

During mitosis, the nuclear envelope dis

Question 18

Ribosomal proteins are synthesized in the nucleolus and then assembled onto rRNAs.

Accepted Answer

A) True 
 B)False

Question 19

What attributes of the locations where replication and transcription occur within the nucleus leads to these sites being designated as "factories"?

Accepted Answer

Lots of DNA replication and transcriptio

Question 20

Nuclear proteins that are stripped of their nuclear localization signal and injected into the cytoplasm of cultured cells will localize

Accepted Answer

A)  to the nucleus. 
B)  in the cytoplasm. 
C)  in a ring around the outside of the nuclear envelope. 
D)  extracellularly. 
A)  to the nucleus. 
B)  in the cytoplasm. 
C)  in a ring around the outside of the nuclear envelope. 
D)  extracellularly.

Where is 5S rRNA synthesized?

Chromatin domains appear to represent discrete functional units that independently regulate gene expression.

Which of the following is not involved in the transport of RNAs out of the nucleus?

How many copies of the large ribosomal RNA gene does the human genome contain?

Polycomb proteins promote heterochromatin formation and gene silencing by

The nucleolus is the site of rRNA synthesis and processing and of ribosomal subunit assembly.

Give one example of how regulation of nuclear protein import is involved in gene regulation.

Within the nucleolus, what functions are associated with the fibrillar center, dense fibrillar component, and granular component?

By restricting the traffic of proteins and RNA across the nuclear envelope, eukaryotic cells can regulate _______ in unique ways.

Which of the following is an example of nucleolar involvement in processing of non-rRNAs?

Transcriptionally active chromatin, which is called _, is decondensed, while transcriptionally inactive chromatin, which is called _, is highly condensed.

What are nuclear speckles?

Most snoRNAs

Proteins called _ act as receptors for cargo protein import into the nucleus, and proteins called _ play the corresponding role in export from the nucleus.

Which of the following are not compartments in the nucleus?

Ribosomal proteins are synthesized in the nucleolus and then assembled onto rRNAs.

What attributes of the locations where replication and transcription occur within the nucleus leads to these sites being designated as "factories"?

Nuclear proteins that are stripped of their nuclear localization signal and injected into the cytoplasm of cultured cells will localize

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Exam 11: The Nucleus

Where is 5S rRNA synthesized?

Chromatin domains appear to represent discrete functional units that independently regulate gene expression.

Which of the following is not involved in the transport of RNAs out of the nucleus?

How many copies of the large ribosomal RNA gene does the human genome contain?

Polycomb proteins promote heterochromatin formation and gene silencing by

The nucleolus is the site of rRNA synthesis and processing and of ribosomal subunit assembly.

Give one example of how regulation of nuclear protein import is involved in gene regulation.

Within the nucleolus, what functions are associated with the fibrillar center, dense fibrillar component, and granular component?

By restricting the traffic of proteins and RNA across the nuclear envelope, eukaryotic cells can regulate _______ in unique ways.

Which of the following is an example of nucleolar involvement in processing of non-rRNAs?

Transcriptionally active chromatin, which is called _______, is decondensed, while transcriptionally inactive chromatin, which is called _______, is highly condensed.

What are nuclear speckles?

Most snoRNAs

Proteins called _______ act as receptors for cargo protein import into the nucleus, and proteins called _______ play the corresponding role in export from the nucleus.

Which of the following are not compartments in the nucleus?

Ribosomal proteins are synthesized in the nucleolus and then assembled onto rRNAs.

What attributes of the locations where replication and transcription occur within the nucleus leads to these sites being designated as "factories"?

Nuclear proteins that are stripped of their nuclear localization signal and injected into the cytoplasm of cultured cells will localize

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Transcriptionally active chromatin, which is called _, is decondensed, while transcriptionally inactive chromatin, which is called _, is highly condensed.

Proteins called _ act as receptors for cargo protein import into the nucleus, and proteins called _ play the corresponding role in export from the nucleus.