Exam 12: Protein Sorting and Transport
Exam 1: An Overview of Cells and Cell Research124 Questions
Exam 2: Molecules and Membranes133 Questions
Exam 3: Bioenergetics and Metabolism138 Questions
Exam 4: Fundamentals of Molecular Biology117 Questions
Exam 5: Genomics, Proteomics, and Systems Biology108 Questions
Exam 6: Genes and Genomes101 Questions
Exam 7: Replication, Maintenance, and Rearrangements of Genomic Dna103 Questions
Exam 8: RNA Synthesis and Processing104 Questions
Exam 9: Transcriptional Regulation and Epigenetics115 Questions
Exam 10: Protein Synthesis, Processing, and Regulation98 Questions
Exam 11: The Nucleus128 Questions
Exam 12: Protein Sorting and Transport110 Questions
Exam 13: Mitochondria, Chloroplasts, and Peroxisomes106 Questions
Exam 14: The Cytoskeleton and Cell Movement106 Questions
Exam 15: The Plasma Membrane109 Questions
Exam 16: Cell Walls, the Extracellular Matrix, and Cell Interactions101 Questions
Exam 17: Cell Signaling114 Questions
Exam 18: The Cell Cycle101 Questions
Exam 19: Cell Death and Cell Renewal107 Questions
Exam 20: Cancer102 Questions
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The major function of the hydrophobic sequence at the amino terminals of proteins that are to be secreted from eukaryotic cells is to target those proteins to the rough ER.
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True
How many Rab proteins have been shown to play a specific role in vesicular transport?
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D
What is the likely transport pathway for lysosomal hydrolases in patients with I-cell disease?
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(Short Answer)
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They are secreted into the extracellular space.
In some proteins, the only transmembrane sequence is located C-terminally in the protein. These proteins are recognized by
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The main method by which a cell gets rid of old, worn-out organelles is exocytosis.
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In cisternal maturation, the carriers for cargo protein transport through the Golgi apparatus are the Golgi _______.
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Synaptic vesicles use a special mode of fusion that is completely different from regulated secretion in a typical secretory cell.
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If secretory proteins are isolated from secretory vesicles and injected into the cytosol, they will
(Multiple Choice)
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The three major classes of vesicle coat proteins are _______, _______, and _______.
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Describe the role of each of the following in targeting and processing proteins in the endoplasmic reticulum.
-A signal recognition particle (SRP)
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What happens to a glycoprotein in the ER lumen if it cannot be folded correctly?
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N-linked oligosaccharides are added in the _______ and modified in the _______.
(Multiple Choice)
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Describe the role of each of the following in targeting and processing proteins in the endoplasmic reticulum.
-Protein disulfide isomerase
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As they emerge from the ribosome, signal sequences are recognized and bound by
(Multiple Choice)
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The signal sequence that targets a nascent polypeptide and its mRNA to the rough ER is rich in _______ amino acids.
(Multiple Choice)
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In polarized epithelial cells, proteins may be specifically targeted to what two membrane domains?
(Short Answer)
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Describe the role of each of the following in targeting and processing proteins in the endoplasmic reticulum.
-A signal sequence
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The transcription factors that direct the unfolded protein response are _______ and _______.
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