Question 1

All molecules found in the nucleus have been transported there via a process that requires ATP.

Accepted Answer

A) True 
 B)False  False

Question 2

Which of the following is a possible intermediate during pre-rRNA processing?

Accepted Answer

A)  An RNA molecule containing 18S + 5.8S rRNAs 
B)  An RNA molecule containing 5.8S + 28S rRNAs 
C)  An RNA molecule containing 5S + 28S rRNAs 
D)  An RNA molecule containing 18S + 28S rRNAs 
A)  An RNA molecule containing 18S + 5.8S rRNAs 
B)  An RNA molecule containing 5.8S + 28S rRNAs 
C)  An RNA molecule containing 5S + 28S rRNAs 
D)  An RNA molecule containing 18S + 28S rRNAs B

Question 3

How does the clustering and transcriptional pattern for eukaryotic ribosomal RNA genes ensure that there will be equal numbers of copies of the major RNAs available for ribosome assembly?

Accepted Answer

Ribosomal genes are organized in tandem repeats that contain one copy each of the 18S, 5.8S, and 28S rRNA sequence as a single gene unit. The transcript contains all three sequences, and hence, each is produced after processing of the pre-rRNA in the same amount. All this is located in the nucleolus. Transcription of 5S rRNA occurs outside the nucleolus and may not be as tightly linked in terms of amount.

Question 4

Chromatin domains are loops of at least _______ base pairs of DNA.

Accepted Answer

A)  1000 
B)  10,000 
C)  100,000 
D)  1,000,000 
A)  1000 
B)  10,000 
C)  100,000 
D)  1,000,000

Question 5

Individual chromosomes occupy discrete territories within the nucleus.

Accepted Answer

A) True 
 B)False

Question 6

Lamins are associated with the inner nuclear envelope membrane via

Accepted Answer

A)  GPI anchors on lamins. 
B)  lipid tails on lamins only. 
C)  lamin-binding proteins in the nuclear envelope membrane only. 
D)  lipid tails on lamins and lamin-binding proteins in the nuclear envelope membrane. 
A)  GPI anchors on lamins. 
B)  lipid tails on lamins only. 
C)  lamin-binding proteins in the nuclear envelope membrane only. 
D)  lipid tails on lamins and lamin-binding proteins in the nuclear envelope membrane.

Question 7

Cleaving of pre-rRNA produces

Accepted Answer

A)  the 28S rRNA. 
B)  the 18S rRNA. 
C)  both 28S and 18S rRNAs. 
D)  the 28S, 18S, and 5.8S rRNAs. 
A)  the 28S rRNA. 
B)  the 18S rRNA. 
C)  both 28S and 18S rRNAs. 
D)  the 28S, 18S, and 5.8S rRNAs.

Question 8

Which statement about heterochromatin is false?

Accepted Answer

A)  It is highly condensed chromatin. 
B)  There are two forms-constitutive and facultative heterochromatin. 
C)  It is transcriptionally active. 
D)  It is largely localized to the nuclear periphery. 
A)  It is highly condensed chromatin. 
B)  There are two forms-constitutive and facultative heterochromatin. 
C)  It is transcriptionally active. 
D)  It is largely localized to the nuclear periphery.

Question 9

What is the function of karyopherins?

Accepted Answer

They are n

Question 10

Underlying the nuclear envelope is the _______, a fibrous meshwork composed of proteins called _______.

Accepted Answer

nuclear la

Question 11

Which statement about snRNAs is true?

Accepted Answer

A)  They are synthesized in the nucleus and function in the cytoplasm. 
B)  They are synthesized in the cytoplasm and function in the nucleus. 
C)  They are synthesized in the nucleus and function in the nucleus without passing into the cytoplasm. 
D)  They are synthesized in the nucleus, move to the cytoplasm to form functional complexes with proteins, and then return to the nucleus. 
A)  They are synthesized in the nucleus and function in the cytoplasm. 
B)  They are synthesized in the cytoplasm and function in the nucleus. 
C)  They are synthesized in the nucleus and function in the nucleus without passing into the cytoplasm. 
D)  They are synthesized in the nucleus, move to the cytoplasm to form functional complexes with proteins, and then return to the nucleus.

Question 12

Unlike eukaryotic cells, prokaryotic cells do not have a nucleus. What are some possible benefits of the evolution of a nucleus in eukaryotes?

Accepted Answer

In contrast to prokaryotes, eukaryotic R

Question 13

What is the average number of replication forks per DNA replication cluster in a mammalian cell nucleus?

Accepted Answer

A)  Approximately 20 
B)  Approximately 200 
C)  Approximately 4,000 
D)  Approximately 8,000 
A)  Approximately 20 
B)  Approximately 200 
C)  Approximately 4,000 
D)  Approximately 8,000

Question 14

A major regulatory protein for nuclear import and export of proteins is the small GTPase _______.

Accepted Answer

The answer of A major regulatory protein for nuclear import...

Question 15

Nuclear speckles are nuclear bodies that contain _______ and snRNPs.

Accepted Answer

The answer of Nuclear speckles are nuclear bodies that contain...

Question 16

Mutations in the fibrous protein underlying the nuclear envelope can cause premature _______, or progeria.

Accepted Answer

The answer of Mutations in the fibrous protein underlying the...

Question 17

The filaments of the nuclear lamina are composed of a type of

Accepted Answer

A)  intermediate filament. 
B)  microtubule. 
C)  microfilament. 
D)  thick filament. 
A)  intermediate filament. 
B)  microtubule. 
C)  microfilament. 
D)  thick filament.

Question 18

The eukaryotic 45S pre-rRNA transcript codes for the

Accepted Answer

A)  28S rRNA. 
B)  28S and 18S rRNAs. 
C)  28S, 18S, and 5.8S rRNAs. 
D)  28S, 18S, 5.8S, and 5S rRNAs. 
A)  28S rRNA. 
B)  28S and 18S rRNAs. 
C)  28S, 18S, and 5.8S rRNAs. 
D)  28S, 18S, 5.8S, and 5S rRNAs.

Question 19

The nuclear envelope is composed of one nuclear membrane and an underlying nuclear lamina.

Accepted Answer

A) True 
 B)False

Question 20

Nuclear pores are organized with _______ symmetry.

Accepted Answer

A)  sixfold 
B)  eightfold 
C)  ninefold 
D)  tenfold 
A)  sixfold 
B)  eightfold 
C)  ninefold 
D)  tenfold

All molecules found in the nucleus have been transported there via a process that requires ATP.

Which of the following is a possible intermediate during pre-rRNA processing?

How does the clustering and transcriptional pattern for eukaryotic ribosomal RNA genes ensure that there will be equal numbers of copies of the major RNAs available for ribosome assembly?

Chromatin domains are loops of at least _______ base pairs of DNA.

Individual chromosomes occupy discrete territories within the nucleus.

Lamins are associated with the inner nuclear envelope membrane via

Cleaving of pre-rRNA produces

Which statement about heterochromatin is false?

What is the function of karyopherins?

Underlying the nuclear envelope is the _, a fibrous meshwork composed of proteins called _.

Which statement about snRNAs is true?

Unlike eukaryotic cells, prokaryotic cells do not have a nucleus. What are some possible benefits of the evolution of a nucleus in eukaryotes?

What is the average number of replication forks per DNA replication cluster in a mammalian cell nucleus?

A major regulatory protein for nuclear import and export of proteins is the small GTPase _______.

Nuclear speckles are nuclear bodies that contain _______ and snRNPs.

Mutations in the fibrous protein underlying the nuclear envelope can cause premature _______, or progeria.

The filaments of the nuclear lamina are composed of a type of

The eukaryotic 45S pre-rRNA transcript codes for the

The nuclear envelope is composed of one nuclear membrane and an underlying nuclear lamina.

Nuclear pores are organized with _______ symmetry.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Exam 11: The Nucleus

All molecules found in the nucleus have been transported there via a process that requires ATP.

Which of the following is a possible intermediate during pre-rRNA processing?

How does the clustering and transcriptional pattern for eukaryotic ribosomal RNA genes ensure that there will be equal numbers of copies of the major RNAs available for ribosome assembly?

Chromatin domains are loops of at least _______ base pairs of DNA.

Individual chromosomes occupy discrete territories within the nucleus.

Lamins are associated with the inner nuclear envelope membrane via

Cleaving of pre-rRNA produces

Which statement about heterochromatin is false?

What is the function of karyopherins?

Underlying the nuclear envelope is the _______, a fibrous meshwork composed of proteins called _______.

Which statement about snRNAs is true?

Unlike eukaryotic cells, prokaryotic cells do not have a nucleus. What are some possible benefits of the evolution of a nucleus in eukaryotes?

What is the average number of replication forks per DNA replication cluster in a mammalian cell nucleus?

A major regulatory protein for nuclear import and export of proteins is the small GTPase _______.

Nuclear speckles are nuclear bodies that contain _______ and snRNPs.

Mutations in the fibrous protein underlying the nuclear envelope can cause premature _______, or progeria.

The filaments of the nuclear lamina are composed of a type of

The eukaryotic 45S pre-rRNA transcript codes for the

The nuclear envelope is composed of one nuclear membrane and an underlying nuclear lamina.

Nuclear pores are organized with _______ symmetry.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Underlying the nuclear envelope is the _, a fibrous meshwork composed of proteins called _.