Question 1

Emery-Dreifuss muscular dystrophy and Hutchinson-Gilford progeria are caused by mutations in genes that code for

Accepted Answer

A)  importin or Ran. 
B)  Polycomb proteins. 
C)  NF-κB. 
D)  A-type nuclear lamins or emerin. 
A)  importin or Ran. 
B)  Polycomb proteins. 
C)  NF-κB. 
D)  A-type nuclear lamins or emerin.

Question 2

The mass of the nuclear pore complex is estimated to be

Accepted Answer

A)  smaller than that of a ribosome. 
B)  about the same as that of a ribosome. 
C)  about five times that of a ribosome. 
D)  about 30 times that of a ribosome. 
A)  smaller than that of a ribosome. 
B)  about the same as that of a ribosome. 
C)  about five times that of a ribosome. 
D)  about 30 times that of a ribosome.

Question 3

Polycomb proteins consist of _______ complex(es) and are concentrated in Polycomb bodies within the nucleus.

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  either 2 or 3, depending on cell type 
A)  1 
B)  2 
C)  3 
D)  either 2 or 3, depending on cell type

Question 4

What modification of nucleotides occurs during processing of pre-rRNA?

Accepted Answer

Addition o

Question 5

Nuclear localization signals are usually short sequences rich in which amino acids?

Accepted Answer

The answer of Nuclear localization signals are usually short sequences...

Question 6

The nuclear envelope consists of what four major components?

Accepted Answer

The inner nuclear membrane, th

Question 7

Small molecules (< 20 kd) enter nuclei by way of

Accepted Answer

A)  passive diffusion through nuclear pore complexes. 
B)  selective transport through nuclear pore complexes. 
C)  active transport across the nuclear envelope membranes. 
D)  passive diffusion across the nuclear envelope membranes. 
A)  passive diffusion through nuclear pore complexes. 
B)  selective transport through nuclear pore complexes. 
C)  active transport across the nuclear envelope membranes. 
D)  passive diffusion across the nuclear envelope membranes.

Question 8

Because of the presence of a nuclear envelope, eukaryotes can perform several functions that prokaryotes cannot. Identify one of these functions.

Accepted Answer

Answers will vary, including p

Question 9

The genes encoding 5.8S, 18S, and 28S ribosome RNA are clustered together in

Accepted Answer

A)  tandem arrays located on one chromosome. 
B)  tandem arrays interspersed with tandem arrays of genes encoding 5S ribosomal RNA. 
C)  tandem arrays located on three chromosomes. 
D)  tandem arrays located on five chromosomes. 
A)  tandem arrays located on one chromosome. 
B)  tandem arrays interspersed with tandem arrays of genes encoding 5S ribosomal RNA. 
C)  tandem arrays located on three chromosomes. 
D)  tandem arrays located on five chromosomes.

Question 10

How does the structure of the outer side of the nuclear pore complex differ from that of the inner side?

Accepted Answer

On the outer side, eight cytoplasmic fil

Question 11

By what mechanism are most nuclear proteins specifically targeted to the nucleus for import?

Accepted Answer

They have a nuclear import signal (a sho

Question 12

Individual chromosomes occupy distinct _______ within the nucleus.

Accepted Answer

territorie

Question 13

Cajal bodies are thought to represent sites of

Accepted Answer

A)  DNA replication. 
B)  snRNA processing and assembly. 
C)  large ribosomal subunit assembly. 
D)  small ribosomal subunit assembly. 
A)  DNA replication. 
B)  snRNA processing and assembly. 
C)  large ribosomal subunit assembly. 
D)  small ribosomal subunit assembly.

Question 14

Receptor-dependent protein transport into the nucleus requires the recognition of a _______ on the cargo protein.

Accepted Answer

nuclear lo

Question 15

The eukaryotic large ribosomal subunit contains the 28S, 5.8S, and 5S rRNAs, plus many different proteins.

Accepted Answer

A) True 
 B)False

Question 16

Entry into the nucleus is limited by the _______ and the _______ complexes.

Accepted Answer

nuclear envelope (nu

Question 17

In eukaryotic cells, the contents of the nucleus are separated from the cytoplasm by the _______.

Accepted Answer

nuclear en

Question 18

In ribosome assembly, _______ that were synthesized in the cytoplasm are assembled into complexes on pre-ribosomal RNA molecules.

Accepted Answer

proteins (

Question 19

The nuclear localization signal is typically a(n) _______, rich in the amino acids _______.

Accepted Answer

A)  α helix; Pro, Lys, and Arg 
B)  α helix; Leu, Phe, and Gly 
C)  short sequence; Lys and Arg 
D)  short sequence; Pro, Leu, and Gly 
A)  α helix; Pro, Lys, and Arg 
B)  α helix; Leu, Phe, and Gly 
C)  short sequence; Lys and Arg 
D)  short sequence; Pro, Leu, and Gly

Question 20

The activity of transcription factors is frequently regulated by controlling their localization within eukaryotic cells, such that only in response to a given stimulus is the transcription factor transported into the nucleus, where it can activate its target genes. For a transcription factor that has a nuclear localization signal (NLS), describe two mechanisms by which regulated transport can occur.

Accepted Answer

Two possible mechanisms involve masking

Emery-Dreifuss muscular dystrophy and Hutchinson-Gilford progeria are caused by mutations in genes that code for

The mass of the nuclear pore complex is estimated to be

Polycomb proteins consist of _______ complex(es) and are concentrated in Polycomb bodies within the nucleus.

What modification of nucleotides occurs during processing of pre-rRNA?

Nuclear localization signals are usually short sequences rich in which amino acids?

The nuclear envelope consists of what four major components?

Small molecules (< 20 kd) enter nuclei by way of

Because of the presence of a nuclear envelope, eukaryotes can perform several functions that prokaryotes cannot. Identify one of these functions.

The genes encoding 5.8S, 18S, and 28S ribosome RNA are clustered together in

How does the structure of the outer side of the nuclear pore complex differ from that of the inner side?

By what mechanism are most nuclear proteins specifically targeted to the nucleus for import?

Individual chromosomes occupy distinct _______ within the nucleus.

Cajal bodies are thought to represent sites of

Receptor-dependent protein transport into the nucleus requires the recognition of a _______ on the cargo protein.

The eukaryotic large ribosomal subunit contains the 28S, 5.8S, and 5S rRNAs, plus many different proteins.

Entry into the nucleus is limited by the _ and the _ complexes.

In eukaryotic cells, the contents of the nucleus are separated from the cytoplasm by the _______.

In ribosome assembly, _______ that were synthesized in the cytoplasm are assembled into complexes on pre-ribosomal RNA molecules.

The nuclear localization signal is typically a(n) _, rich in the amino acids _.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Exam 11: The Nucleus

Emery-Dreifuss muscular dystrophy and Hutchinson-Gilford progeria are caused by mutations in genes that code for

The mass of the nuclear pore complex is estimated to be

Polycomb proteins consist of _______ complex(es) and are concentrated in Polycomb bodies within the nucleus.

What modification of nucleotides occurs during processing of pre-rRNA?

Nuclear localization signals are usually short sequences rich in which amino acids?

The nuclear envelope consists of what four major components?

Small molecules (< 20 kd) enter nuclei by way of

Because of the presence of a nuclear envelope, eukaryotes can perform several functions that prokaryotes cannot. Identify one of these functions.

The genes encoding 5.8S, 18S, and 28S ribosome RNA are clustered together in

How does the structure of the outer side of the nuclear pore complex differ from that of the inner side?

By what mechanism are most nuclear proteins specifically targeted to the nucleus for import?

Individual chromosomes occupy distinct _______ within the nucleus.

Cajal bodies are thought to represent sites of

Receptor-dependent protein transport into the nucleus requires the recognition of a _______ on the cargo protein.

The eukaryotic large ribosomal subunit contains the 28S, 5.8S, and 5S rRNAs, plus many different proteins.

Entry into the nucleus is limited by the _______ and the _______ complexes.

In eukaryotic cells, the contents of the nucleus are separated from the cytoplasm by the _______.

In ribosome assembly, _______ that were synthesized in the cytoplasm are assembled into complexes on pre-ribosomal RNA molecules.

The nuclear localization signal is typically a(n) _______, rich in the amino acids _______.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Entry into the nucleus is limited by the _ and the _ complexes.

The nuclear localization signal is typically a(n) _, rich in the amino acids _.