Question 1

What is the size (in Svedberg units) of the pre-rRNA primary transcript?

Accepted Answer

The answer of What is the size (in Svedberg units)...

Question 2

The most prominent nuclear body is the

Accepted Answer

A)  mitochondrion. 
B)  endoplasmic reticulum. 
C)  histone locus body. 
D)  nucleolus. 
A)  mitochondrion. 
B)  endoplasmic reticulum. 
C)  histone locus body. 
D)  nucleolus.

Question 3

What guides the enzymes that modify rRNAs to their proper positions on the pre-rRNA?

Accepted Answer

The answer of What guides the enzymes that modify rRNAs...

Question 4

The nuclear envelope is continuous with the

Accepted Answer

A)  mitochondrial outer membrane. 
B)  rough endoplasmic reticulum. 
C)  Golgi apparatus. 
D)  plasma membrane. 
A)  mitochondrial outer membrane. 
B)  rough endoplasmic reticulum. 
C)  Golgi apparatus. 
D)  plasma membrane.

Question 5

The directionality of nuclear transport is determined by _______ in the nucleus and _______ in the cytosol.

Accepted Answer

A)  high Ran; low Ran 
B)  low Ran; high Ran 
C)  high Ran/GTP; high Ran/GDP 
D)  high Ran/GDP; high Ran/GTP 
A)  high Ran; low Ran 
B)  low Ran; high Ran 
C)  high Ran/GTP; high Ran/GDP 
D)  high Ran/GDP; high Ran/GTP

Question 6

An important step in the import of the transcription factor NF-$\kappa$B into the nucleus is regulated by a

Accepted Answer

A)  nuclease. 
B)  protease. 
C)  phospholipase. 
D)  plasma membrane receptor that directly phosphorylates I$\kappa$B. 
A)  nuclease. 
B)  protease. 
C)  phospholipase. 
D)  plasma membrane receptor that directly phosphorylates I$\kappa$B.

Question 7

mRNA molecules are exported from the nucleus to the cytoplasm via

Accepted Answer

A)  a consensus sequence located at the 3ʹ terminus. 
B)  the 7-methylguanosine cap structure. 
C)  importin. 
D)  a recruited protein complex. 
A)  a consensus sequence located at the 3ʹ terminus. 
B)  the 7-methylguanosine cap structure. 
C)  importin. 
D)  a recruited protein complex.

Question 8

How can fluorescence in situ hybridization be used to show that chromosomes occupy distinct domains of space within the nucleus?

Accepted Answer

Fluorescently labeled probes t

Question 9

Most snoRNAs function as

Accepted Answer

A)  catalytic RNAs. 
B)  self-replicating RNAs. 
C)  guide RNAs. 
D)  self-splicing RNAs. 
A)  catalytic RNAs. 
B)  self-replicating RNAs. 
C)  guide RNAs. 
D)  self-splicing RNAs.

Question 10

snRNPs that are responsible for pre-mRNA splicing are assembled and stored in

Accepted Answer

A)  Cajal bodies. 
B)  histone locus bodies. 
C)  speckles. 
D)  both Cajal bodies and speckles. 
A)  Cajal bodies. 
B)  histone locus bodies. 
C)  speckles. 
D)  both Cajal bodies and speckles.

Question 11

Ribosomes contain one copy each of 5.8S, 18S, and 28S rRNA. The major mechanism ensuring that each is produced in equal molar amounts is the

Accepted Answer

A)  selective degradation of excess transcripts of the respective rRNAs. 
B)  grouping of the DNA sequences encoding each rRNA into a single rRNA gene. 
C)  outcome of coevolution of the separate genes. 
D)  existence of common sequence features for transcription initiation for the genes encoding each rRNA. 
A)  selective degradation of excess transcripts of the respective rRNAs. 
B)  grouping of the DNA sequences encoding each rRNA into a single rRNA gene. 
C)  outcome of coevolution of the separate genes. 
D)  existence of common sequence features for transcription initiation for the genes encoding each rRNA.

Question 12

How have FISH approaches been applied to studying the arrangement of distribution of gene-rich chromosomes relative the nuclear periphery versus the center of the nucleus?

Accepted Answer

FISH stands for fluorescence in situ hyb

Question 13

In many organisms, the nuclear envelope breaks down during mitosis. As part of this breakdown, the nuclear lamina that underlies the nuclear envelope breaks down. In fact, many investigators think that the breakdown of the lamina initiates envelope breakdown. Propose a reversible mechanism for controlling the polymerization state of the proteins that make up the nuclear lamina.

Accepted Answer

Reversible phosphorylation/dephosphoryla

Question 14

Chromosomes are distributed in the nucleus

Accepted Answer

A)  as cleavage fragments. 
B)  as condensed mitotic chromosomes. 
C)  randomly. 
D)  in distinct territories. 
A)  as cleavage fragments. 
B)  as condensed mitotic chromosomes. 
C)  randomly. 
D)  in distinct territories.

Question 15

In humans, pre-ribosomal RNA consists of a large 45S RNA that contains nucleotide sequences corresponding to _______ different individual rRNAs found within ribosomes.

Accepted Answer

The answer of In humans, pre-ribosomal RNA consists of a...

Question 16

How has chromosome conformation capture (3C) analysis contributed to the identification of interactions within chromosomes?

Accepted Answer

3C has revealed interacting re

Question 17

The major pathway for molecules to pass into and out of the nucleus is through

Accepted Answer

A)  gap junctions between the nuclear envelope membranes. 
B)  porin channels in the nuclear envelope membranes. 
C)  nuclear pore complexes. 
D)  diffusion through the membrane bilayers of the nuclear envelope. 
A)  gap junctions between the nuclear envelope membranes. 
B)  porin channels in the nuclear envelope membranes. 
C)  nuclear pore complexes. 
D)  diffusion through the membrane bilayers of the nuclear envelope.

Question 18

Where are snoRNAs located in the nucleus?

Accepted Answer

The answer of Where are snoRNAs located in the nucleus?...

Question 19

The nuclear lamina is built of proteins called

Accepted Answer

A)  lamins. 
B)  laminins. 
C)  nucleons. 
D)  nucleoplasmins. 
A)  lamins. 
B)  laminins. 
C)  nucleons. 
D)  nucleoplasmins.

Question 20

How does the nuclear envelope differ from the membrane of the endoplasmic reticulum?

Accepted Answer

The outer membrane of the nuclear envelo

What is the size (in Svedberg units) of the pre-rRNA primary transcript?

The most prominent nuclear body is the

What guides the enzymes that modify rRNAs to their proper positions on the pre-rRNA?

The nuclear envelope is continuous with the

The directionality of nuclear transport is determined by _ in the nucleus and _ in the cytosol.

An important step in the import of the transcription factor NF- $\kappa$ B into the nucleus is regulated by a

mRNA molecules are exported from the nucleus to the cytoplasm via

How can fluorescence in situ hybridization be used to show that chromosomes occupy distinct domains of space within the nucleus?

Most snoRNAs function as

snRNPs that are responsible for pre-mRNA splicing are assembled and stored in

Ribosomes contain one copy each of 5.8S, 18S, and 28S rRNA. The major mechanism ensuring that each is produced in equal molar amounts is the

How have FISH approaches been applied to studying the arrangement of distribution of gene-rich chromosomes relative the nuclear periphery versus the center of the nucleus?

Chromosomes are distributed in the nucleus

In humans, pre-ribosomal RNA consists of a large 45S RNA that contains nucleotide sequences corresponding to _______ different individual rRNAs found within ribosomes.

How has chromosome conformation capture (3C) analysis contributed to the identification of interactions within chromosomes?

The major pathway for molecules to pass into and out of the nucleus is through

Where are snoRNAs located in the nucleus?

The nuclear lamina is built of proteins called

How does the nuclear envelope differ from the membrane of the endoplasmic reticulum?

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Exam 11: The Nucleus

What is the size (in Svedberg units) of the pre-rRNA primary transcript?

The most prominent nuclear body is the

What guides the enzymes that modify rRNAs to their proper positions on the pre-rRNA?

The nuclear envelope is continuous with the

The directionality of nuclear transport is determined by _______ in the nucleus and _______ in the cytosol.

An important step in the import of the transcription factor NF- κ\kappaκ B into the nucleus is regulated by a

mRNA molecules are exported from the nucleus to the cytoplasm via

How can fluorescence in situ hybridization be used to show that chromosomes occupy distinct domains of space within the nucleus?

Most snoRNAs function as

snRNPs that are responsible for pre-mRNA splicing are assembled and stored in

Ribosomes contain one copy each of 5.8S, 18S, and 28S rRNA. The major mechanism ensuring that each is produced in equal molar amounts is the

How have FISH approaches been applied to studying the arrangement of distribution of gene-rich chromosomes relative the nuclear periphery versus the center of the nucleus?

Chromosomes are distributed in the nucleus

In humans, pre-ribosomal RNA consists of a large 45S RNA that contains nucleotide sequences corresponding to _______ different individual rRNAs found within ribosomes.

How has chromosome conformation capture (3C) analysis contributed to the identification of interactions within chromosomes?

The major pathway for molecules to pass into and out of the nucleus is through

Where are snoRNAs located in the nucleus?

The nuclear lamina is built of proteins called

How does the nuclear envelope differ from the membrane of the endoplasmic reticulum?

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

The directionality of nuclear transport is determined by _ in the nucleus and _ in the cytosol.

An important step in the import of the transcription factor NF- $\kappa$ B into the nucleus is regulated by a