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In Many Organisms, the Nuclear Envelope Breaks Down During Mitosis

Question 53

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In many organisms, the nuclear envelope breaks down during mitosis. As part of this breakdown, the nuclear lamina that underlies the nuclear envelope breaks down. In fact, many investigators think that the breakdown of the lamina initiates envelope breakdown. Propose a reversible mechanism for controlling the polymerization state of the proteins that make up the nuclear lamina.

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Reversible phosphorylation/dephosphoryla...

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