Question 1

The directionality of nuclear protein import is determined by

Accepted Answer

A)  an unequal distribution of Ran/GTP. 
B)  importin. 
C)  an ion gradient. 
D)  the nuclear lamina. 
A)  an unequal distribution of Ran/GTP. 
B)  importin. 
C)  an ion gradient. 
D)  the nuclear lamina.

Question 2

Why is most heterochromatin bound to the periphery of the nucleus?

Accepted Answer

Proteins associated

Question 3

The principal difference between eukaryotic and prokaryotic cells is that eukaryotic cells have

Accepted Answer

A)  larger ribosomes. 
B)  cell walls, whereas prokaryotic cells do not. 
C)  DNA replication and transcription in the same compartment, whereas prokaryotic cells do not. 
D)  a nucleus, whereas prokaryotic cells do not. 
A)  larger ribosomes. 
B)  cell walls, whereas prokaryotic cells do not. 
C)  DNA replication and transcription in the same compartment, whereas prokaryotic cells do not. 
D)  a nucleus, whereas prokaryotic cells do not.

Question 4

Protein transport into the nucleus occurs by

Accepted Answer

A)  diffusion through the nuclear envelope membranes. 
B)  passive diffusion through nuclear pore complexes. 
C)  selective transport through nuclear pore complexes. 
D)  selective transport through individual subsets of nuclear pore complexes that are specific for individual classes of proteins. 
A)  diffusion through the nuclear envelope membranes. 
B)  passive diffusion through nuclear pore complexes. 
C)  selective transport through nuclear pore complexes. 
D)  selective transport through individual subsets of nuclear pore complexes that are specific for individual classes of proteins.

Question 5

What snRNP modifications take place in Cajal bodies?

Accepted Answer

The snRNA component

Question 6

Small nuclear RNAs are synthesized in the nucleus and function there without ever leaving the nucleus.

Accepted Answer

A) True 
 B)False

Question 7

The most prominent nuclear body, the _______, is the site of ribosome production and rRNA processing and synthesis.

Accepted Answer

The answer of The most prominent nuclear body, the _______,...

Question 8

What is the function of karyopherins?

Accepted Answer

A)  They attach to chromosomes in order to activate heterochromatin. 
B)  They coat chromosomes. 
C)  They define the structure of Cajal bodies. 
D)  They transport macromolecules into or out of the nucleus. 
A)  They attach to chromosomes in order to activate heterochromatin. 
B)  They coat chromosomes. 
C)  They define the structure of Cajal bodies. 
D)  They transport macromolecules into or out of the nucleus.

Question 9

Newly replicated DNA is located in a few hundred spots in the nucleus because

Accepted Answer

A)  there are a few hundred origins of replication per nucleus. 
B)  there are a few thousand origins of replication, but only a few hundred are active at any one time. 
C)  there are a few thousand origins of replication active at any one time, but they are located in a few hundred discrete clusters. 
D)  there are so many charges drawing the DNA molecules together. 
A)  there are a few hundred origins of replication per nucleus. 
B)  there are a few thousand origins of replication, but only a few hundred are active at any one time. 
C)  there are a few thousand origins of replication active at any one time, but they are located in a few hundred discrete clusters. 
D)  there are so many charges drawing the DNA molecules together.

Question 10

The activity of some proteins is regulated by controlling their ability to be imported into the nucleus.

Accepted Answer

A) True 
 B)False

Question 11

Where do the final stages of ribosome subunit formation occur?

Accepted Answer

The answer of Where do the final stages of ribosome...

Question 12

The nucleolus is the site where _______ is(are) assembled.

Accepted Answer

A)  ribosomal subunits 
B)  nuclear pores 
C)  chromatin 
D)  the nuclear matrix 
A)  ribosomal subunits 
B)  nuclear pores 
C)  chromatin 
D)  the nuclear matrix

Question 13

What is the role of nucleotide sequence in mediating the export of ribosomal RNA from the nucleus?

Accepted Answer

The recognized export sequences reside o

Question 14

The nuclear lamina binds to

Accepted Answer

A)  both the inner nuclear envelope membrane and the chromatin. 
B)  the inner nuclear envelope membrane only. 
C)  the chromatin only. 
D)  both the inner and outer nuclear envelope membranes. 
A)  both the inner nuclear envelope membrane and the chromatin. 
B)  the inner nuclear envelope membrane only. 
C)  the chromatin only. 
D)  both the inner and outer nuclear envelope membranes.

Question 15

Ran GAP association with cytoplasmic filaments of the nuclear pore results in the conversion of the nucleotide that is bound to nuclear Ran into

Accepted Answer

A)  ADP. 
B)  GDP. 
C)  ATP. 
D)  GTP. 
A)  ADP. 
B)  GDP. 
C)  ATP. 
D)  GTP.

Question 16

Typically, nuclear localization signals are composed primarily of

Accepted Answer

A)  hydrophobic amino acids. 
B)  acidic amino acids. 
C)  basic amino acids. 
D)  sulfur-containing amino acids. 
A)  hydrophobic amino acids. 
B)  acidic amino acids. 
C)  basic amino acids. 
D)  sulfur-containing amino acids.

Question 17

The fibrous proteins underlying the inner nuclear membrane are

Accepted Answer

A)  band 3s. 
B)  collagens. 
C)  keratins. 
D)  lamins. 
A)  band 3s. 
B)  collagens. 
C)  keratins. 
D)  lamins.

Question 18

To determine a chromosome's distribution within the mammalian nucleus, probes were hybridized to repeated sequences rather than to a single gene. Why?

Accepted Answer

When tandemly arrayed, the repeated sequ

Question 19

Highly condensed, transcriptionally inactive chromatin is called

Accepted Answer

A)  euchromatin. 
B)  heterochromatin. 
C)  a chromatin domain. 
D)  histone-containing chromatin. 
A)  euchromatin. 
B)  heterochromatin. 
C)  a chromatin domain. 
D)  histone-containing chromatin.

Question 20

The nuclear pore complexes provide the only known routes through which molecules can travel between the nucleus and the cytoplasm of interphase cells.

Accepted Answer

A) True 
 B)False

The directionality of nuclear protein import is determined by

Why is most heterochromatin bound to the periphery of the nucleus?

The principal difference between eukaryotic and prokaryotic cells is that eukaryotic cells have

Protein transport into the nucleus occurs by

What snRNP modifications take place in Cajal bodies?

Small nuclear RNAs are synthesized in the nucleus and function there without ever leaving the nucleus.

The most prominent nuclear body, the _______, is the site of ribosome production and rRNA processing and synthesis.

What is the function of karyopherins?

Newly replicated DNA is located in a few hundred spots in the nucleus because

The activity of some proteins is regulated by controlling their ability to be imported into the nucleus.

Where do the final stages of ribosome subunit formation occur?

The nucleolus is the site where _______ is(are) assembled.

What is the role of nucleotide sequence in mediating the export of ribosomal RNA from the nucleus?

The nuclear lamina binds to

Ran GAP association with cytoplasmic filaments of the nuclear pore results in the conversion of the nucleotide that is bound to nuclear Ran into

Typically, nuclear localization signals are composed primarily of

The fibrous proteins underlying the inner nuclear membrane are

To determine a chromosome's distribution within the mammalian nucleus, probes were hybridized to repeated sequences rather than to a single gene. Why?

Highly condensed, transcriptionally inactive chromatin is called

The nuclear pore complexes provide the only known routes through which molecules can travel between the nucleus and the cytoplasm of interphase cells.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Exam 11: The Nucleus

The directionality of nuclear protein import is determined by

Why is most heterochromatin bound to the periphery of the nucleus?

The principal difference between eukaryotic and prokaryotic cells is that eukaryotic cells have

Protein transport into the nucleus occurs by

What snRNP modifications take place in Cajal bodies?

Small nuclear RNAs are synthesized in the nucleus and function there without ever leaving the nucleus.

The most prominent nuclear body, the _______, is the site of ribosome production and rRNA processing and synthesis.

What is the function of karyopherins?

Newly replicated DNA is located in a few hundred spots in the nucleus because

The activity of some proteins is regulated by controlling their ability to be imported into the nucleus.

Where do the final stages of ribosome subunit formation occur?

The nucleolus is the site where _______ is(are) assembled.

What is the role of nucleotide sequence in mediating the export of ribosomal RNA from the nucleus?

The nuclear lamina binds to

Ran GAP association with cytoplasmic filaments of the nuclear pore results in the conversion of the nucleotide that is bound to nuclear Ran into

Typically, nuclear localization signals are composed primarily of

The fibrous proteins underlying the inner nuclear membrane are

To determine a chromosome's distribution within the mammalian nucleus, probes were hybridized to repeated sequences rather than to a single gene. Why?

Highly condensed, transcriptionally inactive chromatin is called

The nuclear pore complexes provide the only known routes through which molecules can travel between the nucleus and the cytoplasm of interphase cells.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters