Question 1

In polarized epithelial cells, membrane proteins containing a dileucine (LL) motif in their cytoplasmic domain are

Accepted Answer

A)  retained in the Golgi apparatus. 
B)  targeted to lysosomes. 
C)  targeted to the basolateral plasma membrane. 
D)  targeted to the apical plasma membrane. 
A)  retained in the Golgi apparatus. 
B)  targeted to lysosomes. 
C)  targeted to the basolateral plasma membrane. 
D)  targeted to the apical plasma membrane.

Question 2

Which of the following proteins do not pass through the Golgi apparatus?

Accepted Answer

A)  Lysosomal enzymes 
B)  Cell surface proteins 
C)  Ribosomal proteins 
D)  Proteins secreted by exocytosis 
A)  Lysosomal enzymes 
B)  Cell surface proteins 
C)  Ribosomal proteins 
D)  Proteins secreted by exocytosis

Question 3

Clathrin-coated vesicles are involved in

Accepted Answer

A)  retrieval of ER resident proteins from the cis Golgi or the ER-Golgi intermediate compartment. 
B)  uptake of extracellular molecules by endocytosis and the transport of molecules from the trans-Golgi network to the lysosomes. 
C)  transport from the ER to the Golgi. 
D)  recycling of Golgi resident proteins during cisternal maturation. 
A)  retrieval of ER resident proteins from the cis Golgi or the ER-Golgi intermediate compartment. 
B)  uptake of extracellular molecules by endocytosis and the transport of molecules from the trans-Golgi network to the lysosomes. 
C)  transport from the ER to the Golgi. 
D)  recycling of Golgi resident proteins during cisternal maturation.

Question 4

The pinching off of budding clathrin-coated vesicles is driven by the action of

Accepted Answer

A)  dynamin and GTP hydrolysis. 
B)  dynamin and ATP hydrolysis. 
C)  GDP bound ARF. 
D)  GTP bound ARF. 
A)  dynamin and GTP hydrolysis. 
B)  dynamin and ATP hydrolysis. 
C)  GDP bound ARF. 
D)  GTP bound ARF.

Question 5

Newly synthesized membrane lipids are found in both halves of a membrane bilayer because they are

Accepted Answer

A)  synthesized on one surface and flipped to the other surface by flippases. 
B)  removed and transported to these locations by lipid transport proteins. 
C)  synthesized on one surface and flipped spontaneously to the other surface. 
D)  synthesized on both surfaces. 
A)  synthesized on one surface and flipped to the other surface by flippases. 
B)  removed and transported to these locations by lipid transport proteins. 
C)  synthesized on one surface and flipped spontaneously to the other surface. 
D)  synthesized on both surfaces.

Question 6

Which of the following lipids is(are) synthesized in the Golgi apparatus?

Accepted Answer

A)  Phospholipids 
B)  Cholesterol 
C)  Ceramide 
D)  Glycolipids 
A)  Phospholipids 
B)  Cholesterol 
C)  Ceramide 
D)  Glycolipids

Question 7

Proteins destined for degradation are delivered to lysosomes by two processes: _______ and _______.

Accepted Answer

autophagy;

Question 8

The Golgi apparatus is the main site of intracellular drug detoxification.

Accepted Answer

A) True 
 B)False

Question 9

Which statement about transmembrane proteins is true?

Accepted Answer

A)  They cross the membrane only once. 
B)  The signal sequences are always cleaved off. 
C)  They usually have one or more $\alpha$ helices spanning the membrane bilayer. 
D)  They are always inserted with the amino terminus on the lumenal side and the carboxyl terminus in the cytosol. 
A)  They cross the membrane only once. 
B)  The signal sequences are always cleaved off. 
C)  They usually have one or more $\alpha$ helices spanning the membrane bilayer. 
D)  They are always inserted with the amino terminus on the lumenal side and the carboxyl terminus in the cytosol.

Question 10

Because of the oxidizing environment of the ER lumen, the formation of _______ bonds is a frequent event.

Accepted Answer

The answer of Because of the oxidizing environment of the...

In polarized epithelial cells, membrane proteins containing a dileucine (LL) motif in their cytoplasmic domain are

Which of the following proteins do not pass through the Golgi apparatus?

Clathrin-coated vesicles are involved in

The pinching off of budding clathrin-coated vesicles is driven by the action of

Newly synthesized membrane lipids are found in both halves of a membrane bilayer because they are

Which of the following lipids is(are) synthesized in the Golgi apparatus?

Proteins destined for degradation are delivered to lysosomes by two processes: _ and _.

The Golgi apparatus is the main site of intracellular drug detoxification.

Which statement about transmembrane proteins is true?

Because of the oxidizing environment of the ER lumen, the formation of _______ bonds is a frequent event.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Exam 12: Protein Sorting and Transport

In polarized epithelial cells, membrane proteins containing a dileucine (LL) motif in their cytoplasmic domain are

Which of the following proteins do not pass through the Golgi apparatus?

Clathrin-coated vesicles are involved in

The pinching off of budding clathrin-coated vesicles is driven by the action of

Newly synthesized membrane lipids are found in both halves of a membrane bilayer because they are

Which of the following lipids is(are) synthesized in the Golgi apparatus?

Proteins destined for degradation are delivered to lysosomes by two processes: _______ and _______.

The Golgi apparatus is the main site of intracellular drug detoxification.

Which statement about transmembrane proteins is true?

Because of the oxidizing environment of the ER lumen, the formation of _______ bonds is a frequent event.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Proteins destined for degradation are delivered to lysosomes by two processes: _ and _.