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Protein Transport into the Endoplasmic Reticulum (ER) or Mitochondria Requires

Question 85

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Protein transport into the endoplasmic reticulum (ER) or mitochondria requires unfolding of the protein and threading the amino acid chain through a channel or pore into the organelle. In contrast, protein transport into the nucleus does not require unfolding of the protein. Why is unfolding unnecessary for nuclear protein import?

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The nuclear pore complex is a huge struc...

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