Question 1

Interferons are small proteins that

Accepted Answer

A)  exert nonspecific antiviral activity 
B)  control cell differentiation 
C)  limit excessive cell proliferation 
D)  modify certain immune processes 
E)  all the above are true 
A)  exert nonspecific antiviral activity 
B)  control cell differentiation 
C)  limit excessive cell proliferation 
D)  modify certain immune processes 
E)  all the above are true E

Question 2

Certain anti-HIV drugs (e.g.,zidovudine,didanosine,and zalcitabine)are known as reverse transcriptase inhibitors because they

Accepted Answer

A)  prevent adsorption/penetration of HIV into T4 lymphocytes 
B)  inhibit transcription of viral RNA to viral DNA 
C)  inhibit insertion of viral DNA into host-cell chromosomes 
D)  all the above are true 
E)  none of the above are true 
A)  prevent adsorption/penetration of HIV into T4 lymphocytes 
B)  inhibit transcription of viral RNA to viral DNA 
C)  inhibit insertion of viral DNA into host-cell chromosomes 
D)  all the above are true 
E)  none of the above are true B

Question 3

Viral infections are often more difficult to treat than other types of infections because

Accepted Answer

A)  viruses contain organelles (ribosomes, mitochondria, etc.) that are naturally resistant to antiviral drugs 
B)  virus particles are much larger in size than other infectious microorganisms such as bacteria 
C)  viruses penetrate into human cells, and cannot be easily killed without harming the human cell 
D)  all the above are true 
E)  none of the above are true 
A)  viruses contain organelles (ribosomes, mitochondria, etc.) that are naturally resistant to antiviral drugs 
B)  virus particles are much larger in size than other infectious microorganisms such as bacteria 
C)  viruses penetrate into human cells, and cannot be easily killed without harming the human cell 
D)  all the above are true 
E)  none of the above are true C

Question 4

All of the following drugs strategies are currently approved by the FDA to treat HIV infection EXCEPT

Accepted Answer

A)  drugs that inhibit the HIV reverse transcriptase enzyme 
B)  drugs that inhibit the HIV protease enzyme 
C)  drugs that inhibit the HIV integrase enzyme 
D)  drugs that inhibit HIV entry into susceptible lymphocytes (i.e, HIV entry inhibitors) 
E)  drugs that stimulate the immune system to recognize and destroy the virus if a person is exposed to HIV (i.e, an HIV vaccine) 
A)  drugs that inhibit the HIV reverse transcriptase enzyme 
B)  drugs that inhibit the HIV protease enzyme 
C)  drugs that inhibit the HIV integrase enzyme 
D)  drugs that inhibit HIV entry into susceptible lymphocytes (i.e, HIV entry inhibitors) 
E)  drugs that stimulate the immune system to recognize and destroy the virus if a person is exposed to HIV (i.e, an HIV vaccine)

Question 5

Reverse transcriptase inhibitors such as zidovudine,didanosine,and lamivudine are especially important for physical therapists because they may cause side effects such as

Accepted Answer

A)  peripheral neuropathy 
B)  myopathy 
C)  joint pain 
D)  all the above are true 
E)  none of the above are true 
A)  peripheral neuropathy 
B)  myopathy 
C)  joint pain 
D)  all the above are true 
E)  none of the above are true

Question 6

In people infected with HIV,highly active antiretroviral therapy (HAART)typically consists of

Accepted Answer

A)  one reverse transcriptase inhibitor at maximal dosage 
B)  one protease inhibitor at maximal dosage 
C)  two drugs, e.g. a RTI plus a protease inhibitor 
D)  two drugs, e.g. a nonnucleoside RTI plus a nucleoside RTI 
E)  three drugs, e.g. two nucleoside RTIs and one nonnucleoside RTI 
A)  one reverse transcriptase inhibitor at maximal dosage 
B)  one protease inhibitor at maximal dosage 
C)  two drugs, e.g. a RTI plus a protease inhibitor 
D)  two drugs, e.g. a nonnucleoside RTI plus a nucleoside RTI 
E)  three drugs, e.g. two nucleoside RTIs and one nonnucleoside RTI

Question 7

An antiviral vaccine is typically created by

Accepted Answer

A)  combining several antiviral drugs in the same pill 
B)  administering a single, strong antiviral drug just after to the onset of infection 
C)  administering a single, strong antiviral drug at the peak of the viral infection 
D)  administering drugs that suppress the immune response to viral infection 
E)  none of the above are true 
A)  combining several antiviral drugs in the same pill 
B)  administering a single, strong antiviral drug just after to the onset of infection 
C)  administering a single, strong antiviral drug at the peak of the viral infection 
D)  administering drugs that suppress the immune response to viral infection 
E)  none of the above are true

Exam 34: Treatment of Infections II: Antiviral Drugs

Interferons are small proteins that

Certain anti-HIV drugs (e.g.,zidovudine,didanosine,and zalcitabine)are known as reverse transcriptase inhibitors because they

Viral infections are often more difficult to treat than other types of infections because

All of the following drugs strategies are currently approved by the FDA to treat HIV infection EXCEPT

Reverse transcriptase inhibitors such as zidovudine,didanosine,and lamivudine are especially important for physical therapists because they may cause side effects such as

In people infected with HIV,highly active antiretroviral therapy (HAART)typically consists of

An antiviral vaccine is typically created by

Basic Principles of Pharmacology

Pharmacokinetics IDrug Administration,Absorption,and Distribution

Pharmacokinetics II: Drug Elimination

Drug Receptors

General Principles of Central Nervous System Pharmacology

Sedative Hypnotic and Anti-anxiety Agents

Drugs to Treat Affective Disorders Depression and Bipolar Syndrome

Antipsychotic Drugs

Antiepileptic Drugs

Pharmacologic Management of Parkinson Disease

General Anesthetics

Local Anesthetics

Skeletal Muscle Relaxants

Opioid Analgesics

Non-steroidal Anti Inflammatory Drugs

Pharmacologic Management of Rheumatoid Arthritis and Osteoarthritis

Patient Controlled Analgesia

Introduction to Autonomic Pharmacology

Cholinergic Drugs

Adrenergic Drugs

Antihypertensive Drugs

Treatment of Angina Pectoris

Treatment of Cardiac Arrhythmias

Treatment of Congestive Heart Failure

Treatment of Coagulation Disorders and Hyperlipidemia

Respiratory Drugs

Gastrointestinal Drugs

Introduction to Endocrine Pharmacology

Adrenocorticosteroids

Male and Female Hormones

Thyroid and Parathyroid Drugs: Agents Affecting Bone Mineralization

Pancreatic Hormones and the Treatment of Diabetes Mellitus

Treatment of Infections I: Antibacterial Drugs

Treatment of Infections III: Antifungal and Antiparasitic Drugs

Cancer Chemotherapy

Immunomodulating Agents

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