Question 1

Benzodiazepines such as clonazepam (Klonopin)are effective in controlling certain seizures because they increase the inhibitory effects of ______ in the CNS.

Accepted Answer

A)  norepinephrine 
B)  acetylcholine 
C)  serotonin 
D)  dopamine 
E)  gamma amino-butyric acid (GAB
A)  
A)  norepinephrine 
B)  acetylcholine 
C)  serotonin 
D)  dopamine 
E)  gamma amino-butyric acid (GAB
A)  E

Question 2

Antiseizure drugs attempt to control neuronal activity via all of the following mechanisms EXCEPT

Accepted Answer

A)  decreasing the effects of excitatory amino acids (glutamate, aspartate) 
B)  increasing the excitatory effects of acetylcholine in the CNS 
C)  decreasing sodium entry into rapidly firing neurons 
D)  increasing the inhibitory effects of gamma aminobutyric acid (GAB
A)  
E)  decreasing the excitatory effects of calcium ions in the CNS 
A)  decreasing the effects of excitatory amino acids (glutamate, aspartate) 
B)  increasing the excitatory effects of acetylcholine in the CNS 
C)  decreasing sodium entry into rapidly firing neurons 
D)  increasing the inhibitory effects of gamma aminobutyric acid (GAB
A)  
E)  decreasing the excitatory effects of calcium ions in the CNS B

Question 3

It appears that antiseizure medications can be successfully discontinued in a large percentage of people with seizure disorders,especially if these patients

Accepted Answer

A)  have been free of seizures for at least 2 years while on medications 
B)  have a normal neurologic examination prior to withdrawal 
C)  were relatively young when the seizures started 
D)  all the above are true 
E)  antiseizure drugs can never be discontinued under any circumstances 
A)  have been free of seizures for at least 2 years while on medications 
B)  have a normal neurologic examination prior to withdrawal 
C)  were relatively young when the seizures started 
D)  all the above are true 
E)  antiseizure drugs can never be discontinued under any circumstances D

Question 4

Newer or "second-generation" antiseizure drugs are helpful in treating certain patients because

Accepted Answer

A)  newer agents generally have milder side effects than traditional antiseizure drugs 
B)  newer agents have favorable pharmacokinetic characteristics (absorption, distribution, metabolism, and so forth) 
C)  newer agents can be combined with a traditional antiseizure drug to provide adequate seizure control in patients who did not respond to a single traditional antiseizure agent 
D)  all the above are true 
E)  none of the above are true 
A)  newer agents generally have milder side effects than traditional antiseizure drugs 
B)  newer agents have favorable pharmacokinetic characteristics (absorption, distribution, metabolism, and so forth) 
C)  newer agents can be combined with a traditional antiseizure drug to provide adequate seizure control in patients who did not respond to a single traditional antiseizure agent 
D)  all the above are true 
E)  none of the above are true

Question 5

Barbiturates are considered to be very safe and effective in the treatment of seizures,but their use is often limited because of their strong tendency to produce

Accepted Answer

A)  sedation 
B)  myopathy 
C)  cardiac dysrhythmias 
D)  hair loss 
E)  glaucoma 
A)  sedation 
B)  myopathy 
C)  cardiac dysrhythmias 
D)  hair loss 
E)  glaucoma

Question 6

Neuropathic pain and certain other chronic pain syndromes may respond to treatment with _____,presumably because these drugs reduce excitation in specific pain pathways in the CNS.

Accepted Answer

A)  amphetamines such as dextroamphetamine 
B)  antiseizure drugs such as gabapentin (Neurontin) and pregabalin (Lyrica) 
C)  anticholinergic drugs such as atropine 
D)  all the above 
E)  none of the above 
A)  amphetamines such as dextroamphetamine 
B)  antiseizure drugs such as gabapentin (Neurontin) and pregabalin (Lyrica) 
C)  anticholinergic drugs such as atropine 
D)  all the above 
E)  none of the above

Exam 9: Antiepileptic Drugs

Benzodiazepines such as clonazepam (Klonopin)are effective in controlling certain seizures because they increase the inhibitory effects of ______ in the CNS.

Antiseizure drugs attempt to control neuronal activity via all of the following mechanisms EXCEPT

It appears that antiseizure medications can be successfully discontinued in a large percentage of people with seizure disorders,especially if these patients

Newer or "second-generation" antiseizure drugs are helpful in treating certain patients because

Barbiturates are considered to be very safe and effective in the treatment of seizures,but their use is often limited because of their strong tendency to produce

Neuropathic pain and certain other chronic pain syndromes may respond to treatment with _____,presumably because these drugs reduce excitation in specific pain pathways in the CNS.

Basic Principles of Pharmacology

Pharmacokinetics IDrug Administration,Absorption,and Distribution

Pharmacokinetics II: Drug Elimination

Drug Receptors

General Principles of Central Nervous System Pharmacology

Sedative Hypnotic and Anti-anxiety Agents

Drugs to Treat Affective Disorders Depression and Bipolar Syndrome

Antipsychotic Drugs

Pharmacologic Management of Parkinson Disease

General Anesthetics

Local Anesthetics

Skeletal Muscle Relaxants

Opioid Analgesics

Non-steroidal Anti Inflammatory Drugs

Pharmacologic Management of Rheumatoid Arthritis and Osteoarthritis

Patient Controlled Analgesia

Introduction to Autonomic Pharmacology

Cholinergic Drugs

Adrenergic Drugs

Antihypertensive Drugs

Treatment of Angina Pectoris

Treatment of Cardiac Arrhythmias

Treatment of Congestive Heart Failure

Treatment of Coagulation Disorders and Hyperlipidemia

Respiratory Drugs

Gastrointestinal Drugs

Introduction to Endocrine Pharmacology

Adrenocorticosteroids

Male and Female Hormones

Thyroid and Parathyroid Drugs: Agents Affecting Bone Mineralization

Pancreatic Hormones and the Treatment of Diabetes Mellitus

Treatment of Infections I: Antibacterial Drugs

Treatment of Infections II: Antiviral Drugs

Treatment of Infections III: Antifungal and Antiparasitic Drugs

Cancer Chemotherapy

Immunomodulating Agents

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