Question 1

Natural and synthetic opioid drugs _____ gastrointestinal motility,and are therefore useful in treating _____.

Accepted Answer

A)  increase; diarrhea 
B)  decrease; diarrhea 
C)  increase; constipation 
D)  decrease; constipation 
E)  none of the above are true; opioids do not affect gastrointestinal motility 
A)  increase; diarrhea 
B)  decrease; diarrhea 
C)  increase; constipation 
D)  decrease; constipation 
E)  none of the above are true; opioids do not affect gastrointestinal motility B

Question 2

Proton pump inhibitors such as omeprazole (Prilosec)and esomeprazole (Nexium)are useful in reducing gastric acid secretion because they

Accepted Answer

A)  contain a base that chemically neutralizes gastric acid 
B)  block the effects of histamine on stomach H2 receptors 
C)  inhibit the enzyme that secretes acid from gastric parietal cells into the lumen of the stomach 
D)  inhibit the enzyme that transports sodium out of gastric parietal cells, and transports potassium into these cells 
E)  none of the above are true; these drugs are not useful in reducing gastric acid secretion 
A)  contain a base that chemically neutralizes gastric acid 
B)  block the effects of histamine on stomach H2 receptors 
C)  inhibit the enzyme that secretes acid from gastric parietal cells into the lumen of the stomach 
D)  inhibit the enzyme that transports sodium out of gastric parietal cells, and transports potassium into these cells 
E)  none of the above are true; these drugs are not useful in reducing gastric acid secretion C

Question 3

Most antacid medications contain a chemical base that neutalizes excess _____ ions in the stomach,thereby _____ intragastric pH.

Accepted Answer

A)  hydrogen; increasing 
B)  hydrogen; decreasing 
C)  sodium; increasing 
D)  sodium; decreasing 
E)  calcium; increasing 
A)  hydrogen; increasing 
B)  hydrogen; decreasing 
C)  sodium; increasing 
D)  sodium; decreasing 
E)  calcium; increasing A

Question 4

In many people with gastric ulcers,antibacterial drugs are often combined with proton pump inhibitors to help eliminate ________ infection as a potentiating factor in ulcer formation.

Accepted Answer

A)  h. pylori 
B)  streptococcal 
C)  e. coli 
D)  girardia 
E)  p. aeruginosa 
A)  h. pylori 
B)  streptococcal 
C)  e. coli 
D)  girardia 
E)  p. aeruginosa

Question 5

To improve the health and well-being of people with cystic fibrosis (CF),____ can be given to ____.

Accepted Answer

A)  digestant preparations that contain pancreatic enzymes and bile salts; improve digestion and absorption of nutrients 
B)  products that contain deoxyribonuclease enzymes; decrease the viscosity of mucous in the respiratory tract 
C)  glucocorticoids; decrease inflammation in the airway 
D)  nonsteroidal anti-inflammatory drugs; decrease inflammation in the airway 
E)  all the above 
A)  digestant preparations that contain pancreatic enzymes and bile salts; improve digestion and absorption of nutrients 
B)  products that contain deoxyribonuclease enzymes; decrease the viscosity of mucous in the respiratory tract 
C)  glucocorticoids; decrease inflammation in the airway 
D)  nonsteroidal anti-inflammatory drugs; decrease inflammation in the airway 
E)  all the above

Question 6

Prolonged or excessive use of antacids should be avoided because

Accepted Answer

A)  these drugs can alter the metabolism of other drugs that rely on gastric acidity to activate the drug 
B)  these drugs can affect the elimination of other drugs by altering urinary pH 
C)  these drugs can cause other GI problems such as constipation or diarrhea 
D)  all the above are true 
E)  none of the above are true 
A)  these drugs can alter the metabolism of other drugs that rely on gastric acidity to activate the drug 
B)  these drugs can affect the elimination of other drugs by altering urinary pH 
C)  these drugs can cause other GI problems such as constipation or diarrhea 
D)  all the above are true 
E)  none of the above are true

Question 7

Drugs such as cimetidine and ranitidine that selectively block histamine type 2 (H2)receptors on stomach parietal cells

Accepted Answer

A)  prevent the histamine-activated release of gastric acid 
B)  are available only by prescription 
C)  are known as antihistamines 
D)  all of the above are true 
E)  none of the above are true 
A)  prevent the histamine-activated release of gastric acid 
B)  are available only by prescription 
C)  are known as antihistamines 
D)  all of the above are true 
E)  none of the above are true

Question 8

Daily or indiscriminate use of laxatives should be avoided because excessive use of these drugs can cause

Accepted Answer

A)  excessive loss of fluids and electrolytes 
B)  irritation of the lower GI tract 
C)  impairment of loss of normal mechanisms governing evacuation and defecation 
D)  all of the above are true 
E)  none of the above are true 
A)  excessive loss of fluids and electrolytes 
B)  irritation of the lower GI tract 
C)  impairment of loss of normal mechanisms governing evacuation and defecation 
D)  all of the above are true 
E)  none of the above are true

Exam 27: Gastrointestinal Drugs

Natural and synthetic opioid drugs _____ gastrointestinal motility,and are therefore useful in treating _____.

Proton pump inhibitors such as omeprazole (Prilosec)and esomeprazole (Nexium)are useful in reducing gastric acid secretion because they

Most antacid medications contain a chemical base that neutalizes excess _____ ions in the stomach,thereby _____ intragastric pH.

In many people with gastric ulcers,antibacterial drugs are often combined with proton pump inhibitors to help eliminate ________ infection as a potentiating factor in ulcer formation.

To improve the health and well-being of people with cystic fibrosis (CF),____ can be given to ____.

Prolonged or excessive use of antacids should be avoided because

Drugs such as cimetidine and ranitidine that selectively block histamine type 2 (H2)receptors on stomach parietal cells

Daily or indiscriminate use of laxatives should be avoided because excessive use of these drugs can cause

Basic Principles of Pharmacology

Pharmacokinetics IDrug Administration,Absorption,and Distribution

Pharmacokinetics II: Drug Elimination

Drug Receptors

General Principles of Central Nervous System Pharmacology

Sedative Hypnotic and Anti-anxiety Agents

Drugs to Treat Affective Disorders Depression and Bipolar Syndrome

Antipsychotic Drugs

Antiepileptic Drugs

Pharmacologic Management of Parkinson Disease

General Anesthetics

Local Anesthetics

Skeletal Muscle Relaxants

Opioid Analgesics

Non-steroidal Anti Inflammatory Drugs

Pharmacologic Management of Rheumatoid Arthritis and Osteoarthritis

Patient Controlled Analgesia

Introduction to Autonomic Pharmacology

Cholinergic Drugs

Adrenergic Drugs

Antihypertensive Drugs

Treatment of Angina Pectoris

Treatment of Cardiac Arrhythmias

Treatment of Congestive Heart Failure

Treatment of Coagulation Disorders and Hyperlipidemia

Respiratory Drugs

Introduction to Endocrine Pharmacology

Adrenocorticosteroids

Male and Female Hormones

Thyroid and Parathyroid Drugs: Agents Affecting Bone Mineralization

Pancreatic Hormones and the Treatment of Diabetes Mellitus

Treatment of Infections I: Antibacterial Drugs

Treatment of Infections II: Antiviral Drugs

Treatment of Infections III: Antifungal and Antiparasitic Drugs

Cancer Chemotherapy

Immunomodulating Agents

Filters

Natural and synthetic opioid drugs _ gastrointestinal motility,and are therefore useful in treating _.

Most antacid medications contain a chemical base that neutalizes excess _ ions in the stomach,thereby _ intragastric pH.

To improve the health and well-being of people with cystic fibrosis (CF), can be given to .