Proton Pump Inhibitors Such as Omeprazole (Prilosec)and Esomeprazole (Nexium)are Useful

Proton pump inhibitors such as omeprazole (Prilosec) and esomeprazole (Nexium) are useful in reducing gastric acid secretion because they

A) contain a base that chemically neutralizes gastric acid
B) block the effects of histamine on stomach H2 receptors
C) inhibit the enzyme that secretes acid from gastric parietal cells into the lumen of the stomach
D) inhibit the enzyme that transports sodium out of gastric parietal cells, and transports potassium into these cells
E) none of the above are true; these drugs are not useful in reducing gastric acid secretion

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