Question 1

Beta blockers are so named because they block the effects of _______ on the heart.

Accepted Answer

A)  epinephrine 
B)  norepinephrine 
C)  acetylcholine 
D)  all the above are true 
E)  A and B only are true 
A)  epinephrine 
B)  norepinephrine 
C)  acetylcholine 
D)  all the above are true 
E)  A and B only are true E

Question 2

Systemic heat (e.g.Hubbard tank)should be avoided in patients taking ______ drugs because the combination of these two interventions will cause excessive

Accepted Answer

A)  vasodilators 
B)  alpha-2 antagonists 
C)  beta-1 agonists 
D)  beta-2 agonists 
E)  all the above are true 
A)  vasodilators 
B)  alpha-2 antagonists 
C)  beta-1 agonists 
D)  beta-2 agonists 
E)  all the above are true A

Question 3

Nonselective beta blockers may produce bronchoconstriction in patients with asthma and similar respiratory disorders because nonselective beta blockers

Accepted Answer

A)  stimulate beta-1 receptors on the lungs 
B)  block beta-1 receptors on the lungs 
C)  stimulate beta-2 receptors on the lungs 
D)  block beta-2 receptors on the lungs 
E)  stimulate alpha-1 receptors on the lungs 
A)  stimulate beta-1 receptors on the lungs 
B)  block beta-1 receptors on the lungs 
C)  stimulate beta-2 receptors on the lungs 
D)  block beta-2 receptors on the lungs 
E)  stimulate alpha-1 receptors on the lungs D

Question 4

Abnormally high activity in the renin-angiotensin system can be controlled by drugs that directly

Accepted Answer

A)  block angiotensin II receptors on cardiovascular tissues 
B)  inhibit the production of angiotensin II 
C)  inhibit the production of angiotensin I 
D)  all the above are true 
E)  only A and B are true 
A)  block angiotensin II receptors on cardiovascular tissues 
B)  inhibit the production of angiotensin II 
C)  inhibit the production of angiotensin I 
D)  all the above are true 
E)  only A and B are true

Question 5

Presynaptic adrenergic inhibitors such as reserpine decrease activity at peripheral arterioles by impairing the release of

Accepted Answer

A)  epinephrine 
B)  norepinephrine 
C)  acetylcholine 
D)  dopamine 
E)  5-hydroxytryptamine (serotonin) 
A)  epinephrine 
B)  norepinephrine 
C)  acetylcholine 
D)  dopamine 
E)  5-hydroxytryptamine (serotonin)

Question 6

Sympatholytic drugs such prazosin and doxazosin can directly decrease vascular resistance by

Accepted Answer

A)  stimulating alpha-1 receptors on the arteriole 
B)  blocking alpha-1 receptors on the arteriole 
C)  stimulating alpha-2 receptors on the arteriole 
D)  blocking alpha-2 receptors on the arteriole 
E)  stimulating beta-1 receptors on the arteriole 
A)  stimulating alpha-1 receptors on the arteriole 
B)  blocking alpha-1 receptors on the arteriole 
C)  stimulating alpha-2 receptors on the arteriole 
D)  blocking alpha-2 receptors on the arteriole 
E)  stimulating beta-1 receptors on the arteriole

Question 7

Abnormally high activity in the renin-angiotensin system should be controlled pharmacologically because increased production of ____ causes ____.

Accepted Answer

A)  angiotensin I; cardiac arrhythmias 
B)  angiotensin II; vascular smooth muscle hypertrophy 
C)  angiotensin I; angina pectoris 
D)  angiotensin II; cardiac arrhythmias 
E)  angiotensin I; vascular smooth muscle atrophy 
A)  angiotensin I; cardiac arrhythmias 
B)  angiotensin II; vascular smooth muscle hypertrophy 
C)  angiotensin I; angina pectoris 
D)  angiotensin II; cardiac arrhythmias 
E)  angiotensin I; vascular smooth muscle atrophy

Question 8

Beta blockers are said to be cardioselective if they bind preferentially to

Accepted Answer

A)  beta-1 receptors 
B)  beta-2 receptors 
C)  beta-3 receptors 
D)  all the above are true 
A)  beta-1 receptors 
B)  beta-2 receptors 
C)  beta-3 receptors 
D)  all the above are true

Question 9

A sudden severe,life-threatening increase in blood pressure (autonomic crisis)should be treated with

Accepted Answer

A)  diuretics 
B)  alpha-1 agonists 
C)  alpha-2 antagonists 
D)  beta-agonists 
E)  ganglionic blockers 
A)  diuretics 
B)  alpha-1 agonists 
C)  alpha-2 antagonists 
D)  beta-agonists 
E)  ganglionic blockers

Question 10

Certain beta-blockers such as pindolol and acebutolol are valuable because they block the effects of excessive endogenous catecholamines while still producing a normal background level of sympathetic stimulation to the heart.These beta blockers are said to have

Accepted Answer

A)  nonselective sympatholytic activity 
B)  intrinsic sympatholytic activity 
C)  intrinsic sympathomimetic activity 
D)  extrinsic sympatholytic activity 
E)  selective sympatholytic activity 
A)  nonselective sympatholytic activity 
B)  intrinsic sympatholytic activity 
C)  intrinsic sympathomimetic activity 
D)  extrinsic sympatholytic activity 
E)  selective sympatholytic activity

Question 11

Angiotensin converting enzyme (ACE)inhibitors can help _____ blood pressure by _____ the formation of angiotensin II.

Accepted Answer

A)  increase; increasing 
B)  increasing; decreasing 
C)  decreasing; increasing 
D)  decrease; decreasing 
E)  none of the above are true 
A)  increase; increasing 
B)  increasing; decreasing 
C)  decreasing; increasing 
D)  decrease; decreasing 
E)  none of the above are true

Question 12

If they stand up suddenly,patients taking antihypertensive medications may be more susceptible to a sudden ____ in blood pressure known commonly as _____.

Accepted Answer

A)  decrease; orthostatic hypotension 
B)  increase; orthostatic hypotension 
C)  decrease; orthostatic hypertension 
D)  increase; orthostatic hypertension 
E)  decrease; malignant hypertension 
A)  decrease; orthostatic hypotension 
B)  increase; orthostatic hypotension 
C)  decrease; orthostatic hypertension 
D)  increase; orthostatic hypertension 
E)  decrease; malignant hypertension

Question 13

Diuretics ______ the excretion of water by _______ sodium reabsorption at the kidneys.

Accepted Answer

A)  increase; inhibiting 
B)  decrease; inhibiting 
C)  increase; stimulating 
D)  decrease; stimulating 
A)  increase; inhibiting 
B)  decrease; inhibiting 
C)  increase; stimulating 
D)  decrease; stimulating

Question 14

Alpha blockers may cause a sudden fall in blood pressure which results in a compensatory increase in heart rate.This increased heart rate is known as _______,and can be treated by administering ______ along with the alpha blocker.

Accepted Answer

A)  reflex tachycardia; a diuretic 
B)  orthostatic hypotension; a diuretic 
C)  reflex tachycardia; a beta blocker 
D)  orthostatic hypotension; a beta blocker 
E)  reflex tachycardia; a beta-1 receptor agonist 
A)  reflex tachycardia; a diuretic 
B)  orthostatic hypotension; a diuretic 
C)  reflex tachycardia; a beta blocker 
D)  orthostatic hypotension; a beta blocker 
E)  reflex tachycardia; a beta-1 receptor agonist

Question 15

Patients who overdose on diuretics

Accepted Answer

A)  may become hyponatremic 
B)  may become hypokalemic 
C)  may lose too much fluid from the vascular system 
D)  all the above are true 
A)  may become hyponatremic 
B)  may become hypokalemic 
C)  may lose too much fluid from the vascular system 
D)  all the above are true

Question 16

Calcium channel blockers can help reduce high blood pressure by

Accepted Answer

A)  stimulating the sinoatrial node in the heart 
B)  stimulating the atrioventricular node in the heart 
C)  inhibiting the vasomotor control center in the brainstem 
D)  inhibiting vascular smooth muscle contraction 
E)  increasing renal sodium and water excretion 
A)  stimulating the sinoatrial node in the heart 
B)  stimulating the atrioventricular node in the heart 
C)  inhibiting the vasomotor control center in the brainstem 
D)  inhibiting vascular smooth muscle contraction 
E)  increasing renal sodium and water excretion

Question 17

Centrally acting sympatholytic drugs decrease blood pressure by affecting sympathetic discharge from

Accepted Answer

A)  the sympathetic chain ganglia 
B)  the spinal cord 
C)  the brainstem 
D)  the cerebellum 
E)  the hypothalamus 
A)  the sympathetic chain ganglia 
B)  the spinal cord 
C)  the brainstem 
D)  the cerebellum 
E)  the hypothalamus

Question 18

Nitric oxide can be used to reduce vascular resistance and decrease arterial pressure in specific hypertensive syndromes because nitric oxide

Accepted Answer

A)  inhibits (blocks) beta-1 receptors on the heart 
B)  inhibits (blocks) beta-2 receptors on the heart 
C)  inhibits (blocks) alpha-1 receptors on arteriole smooth muscle 
D)  directly inhibits the contraction of vascular smooth muscle 
E)  none of the above are true; nitric oxide is not useful in reducing arterial pressure 
A)  inhibits (blocks) beta-1 receptors on the heart 
B)  inhibits (blocks) beta-2 receptors on the heart 
C)  inhibits (blocks) alpha-1 receptors on arteriole smooth muscle 
D)  directly inhibits the contraction of vascular smooth muscle 
E)  none of the above are true; nitric oxide is not useful in reducing arterial pressure

Question 19

In addition to reducing the formation of angiotensin II,drugs that inhibit angiotensin-converting enzyme (ACE inhibitors)can reduce hypertension by ____ the effects of ____.

Accepted Answer

A)  increasing; bradykinin 
B)  decreasing; aldosterone 
C)  increasing; norepinephrine 
D)  A and B only 
E)  all the above 
A)  increasing; bradykinin 
B)  decreasing; aldosterone 
C)  increasing; norepinephrine 
D)  A and B only 
E)  all the above

Exam 21: Antihypertensive Drugs

Beta blockers are so named because they block the effects of _______ on the heart.

Systemic heat (e.g.Hubbard tank)should be avoided in patients taking ______ drugs because the combination of these two interventions will cause excessive

Nonselective beta blockers may produce bronchoconstriction in patients with asthma and similar respiratory disorders because nonselective beta blockers

Abnormally high activity in the renin-angiotensin system can be controlled by drugs that directly

Presynaptic adrenergic inhibitors such as reserpine decrease activity at peripheral arterioles by impairing the release of

Sympatholytic drugs such prazosin and doxazosin can directly decrease vascular resistance by

Abnormally high activity in the renin-angiotensin system should be controlled pharmacologically because increased production of ____ causes ____.

Beta blockers are said to be cardioselective if they bind preferentially to

A sudden severe,life-threatening increase in blood pressure (autonomic crisis)should be treated with

Certain beta-blockers such as pindolol and acebutolol are valuable because they block the effects of excessive endogenous catecholamines while still producing a normal background level of sympathetic stimulation to the heart.These beta blockers are said to have

Angiotensin converting enzyme (ACE)inhibitors can help _____ blood pressure by _____ the formation of angiotensin II.

If they stand up suddenly,patients taking antihypertensive medications may be more susceptible to a sudden ____ in blood pressure known commonly as _____.

Diuretics ______ the excretion of water by _______ sodium reabsorption at the kidneys.

Alpha blockers may cause a sudden fall in blood pressure which results in a compensatory increase in heart rate.This increased heart rate is known as _______,and can be treated by administering ______ along with the alpha blocker.

Patients who overdose on diuretics

Calcium channel blockers can help reduce high blood pressure by

Centrally acting sympatholytic drugs decrease blood pressure by affecting sympathetic discharge from

Nitric oxide can be used to reduce vascular resistance and decrease arterial pressure in specific hypertensive syndromes because nitric oxide

In addition to reducing the formation of angiotensin II,drugs that inhibit angiotensin-converting enzyme (ACE inhibitors)can reduce hypertension by ____ the effects of ____.

Basic Principles of Pharmacology

Pharmacokinetics IDrug Administration,Absorption,and Distribution

Pharmacokinetics II: Drug Elimination

Drug Receptors

General Principles of Central Nervous System Pharmacology

Sedative Hypnotic and Anti-anxiety Agents

Drugs to Treat Affective Disorders Depression and Bipolar Syndrome

Antipsychotic Drugs

Antiepileptic Drugs

Pharmacologic Management of Parkinson Disease

General Anesthetics

Local Anesthetics

Skeletal Muscle Relaxants

Opioid Analgesics

Non-steroidal Anti Inflammatory Drugs

Pharmacologic Management of Rheumatoid Arthritis and Osteoarthritis

Patient Controlled Analgesia

Introduction to Autonomic Pharmacology

Cholinergic Drugs

Adrenergic Drugs

Treatment of Angina Pectoris

Treatment of Cardiac Arrhythmias

Treatment of Congestive Heart Failure

Treatment of Coagulation Disorders and Hyperlipidemia

Respiratory Drugs

Gastrointestinal Drugs

Introduction to Endocrine Pharmacology

Adrenocorticosteroids

Male and Female Hormones

Thyroid and Parathyroid Drugs: Agents Affecting Bone Mineralization

Pancreatic Hormones and the Treatment of Diabetes Mellitus

Treatment of Infections I: Antibacterial Drugs

Treatment of Infections II: Antiviral Drugs

Treatment of Infections III: Antifungal and Antiparasitic Drugs

Cancer Chemotherapy

Immunomodulating Agents

Filters

Abnormally high activity in the renin-angiotensin system should be controlled pharmacologically because increased production of causes .

Angiotensin converting enzyme (ACE)inhibitors can help _ blood pressure by _ the formation of angiotensin II.

If they stand up suddenly,patients taking antihypertensive medications may be more susceptible to a sudden in blood pressure known commonly as _.

Diuretics the excretion of water by _ sodium reabsorption at the kidneys.

Alpha blockers may cause a sudden fall in blood pressure which results in a compensatory increase in heart rate.This increased heart rate is known as _,and can be treated by administering along with the alpha blocker.

In addition to reducing the formation of angiotensin II,drugs that inhibit angiotensin-converting enzyme (ACE inhibitors)can reduce hypertension by the effects of .