Exam 31: Thyroid and Parathyroid Drugs: Agents Affecting Bone Mineralization

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All of the following drug strategies can be used as part of a comprehensive plan to increase bone mineral density in postmenopausal women EXCEPT

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C

Calcimimetics like cinacalcet (Sensipar)that mimic the effects of endogenous calcium can help ____ parathyroid hormone (PTH)release,thus helping to ____ excessive bone breakdown in people with parathyroid tumors or other conditions that cause parathyroid hyperactivity.

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C

Treatment of hypothyroidism typically consists of

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E

Small amounts of _____ must be ingested in the diet so that the thyroid gland can synthesize thyroid hormones.

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Prolonged,large doses of parathyroid hormone ______ bone breakdown,and small,intermittent amounts of parathyroid hormone ______ bone synthesis and remodeling.

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All of the following symptoms are associated with hyperthyroidism EXCEPT

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Vitamin D and several related metabolites enhance bone formation by _____ intestinal absorption of calcium and phosphate,and _____ renal excretion of calcium and phosphate.

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Bisphosphonates such as alendronate (Fosamax)and pamidronate (Aredia)reduce bone resorption in osteoporosis and similar conditions by

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Parathyroid hormone ______ plasma calcium levels by ______ calcium resorption from bone.

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