Exam 2: Pharmacokinetics IDrug Administration,Absorption,and Distribution

Drug developers are exploring nanotechnology (i.e.,the use of very small particles with specific physical properties)as a way to

The ______ effect occurs when drugs are transported initially to the liver where a significant amount of the drug may be metabolized and destroyed before the drug reaches its primary site of action.

Carrier specificity,expernditure of energy,and ability to transport substances against a concentration gradient are all characteristics of

The extent to which a drug reaches the systemic circulation is referred to as

All of the following are parenteral routes of drug administration EXCEPT the ____ route.

When crossing cell membranes,drugs will diffuse more readily through the lipid layer if they are

This first pass effect is of particular concern when drugs are administered

The primary site for drug storage in the body is

Osmosis refers to the special case of diffusion where the diffusing substance is

A drug that has a volume of distribution of approximately 42 L will typically be

Iontophoresis,phonophoresis,and medicated patches all use the _____ route to administer drugs.