Question 1

The point at which there is no further increase in the response to a drug even if the dosage continues to be increased is known as the

Accepted Answer

A)  ceiling effect 
B)  maximal efficacy 
C)  potency 
D)  all of the above 
E)  A and B only 
A)  ceiling effect 
B)  maximal efficacy 
C)  potency 
D)  all of the above 
E)  A and B only E

Question 2

In general,the greater the value of the _______,the safer the drug is considered to be.

Accepted Answer

A)  median effective dose 
B)  threshold dose 
C)  therapeutic index (TI) 
D)  ceiling effect 
E)  potency index 
A)  median effective dose 
B)  threshold dose 
C)  therapeutic index (TI) 
D)  ceiling effect 
E)  potency index C

Question 3

Toxicology is

Accepted Answer

A)  the study of the harmful effects of chemicals 
B)  the study of a drug's beneficial effects 
C)  the analysis of drug absorption, distribution, and metabolism 
D)  the preparation and dispensing of therapeutic medications 
E)  the analysis of a drug's molecular structure 
A)  the study of the harmful effects of chemicals 
B)  the study of a drug's beneficial effects 
C)  the analysis of drug absorption, distribution, and metabolism 
D)  the preparation and dispensing of therapeutic medications 
E)  the analysis of a drug's molecular structure A

Question 4

When two drugs are compared,the drug that requires a lower dosage to produce the same effect as a higher dose of the second drug is said to

Accepted Answer

A)  be more potent 
B)  be impotent 
C)  have a great maximal efficacy 
D)  have a greater therapeutic index 
E)  be pharmacosuperior 
A)  be more potent 
B)  be impotent 
C)  have a great maximal efficacy 
D)  have a greater therapeutic index 
E)  be pharmacosuperior

Question 5

During drug testing and approval,the drug is usually tested in a relatively small sample (200 to 300 people)with a specific disease or pathologic condition during

Accepted Answer

A)  preclinical trials 
B)  phase 1 clinical trials 
C)  phase 2 clinical trials 
D)  postmarketing surveillance 
A)  preclinical trials 
B)  phase 1 clinical trials 
C)  phase 2 clinical trials 
D)  postmarketing surveillance

Question 6

The use of specific drugs to prevent,treat,or diagnose disease is known as

Accepted Answer

A)  toxicology 
B)  pharmacokinetics 
C)  pharmacotherapeutics 
D)  toxicokinetics 
E)  dynamic equilibrium 
A)  toxicology 
B)  pharmacokinetics 
C)  pharmacotherapeutics 
D)  toxicokinetics 
E)  dynamic equilibrium

Question 7

The generic name of a drug

Accepted Answer

A)  is also known as the "official" or "nonproprietary" name 
B)  is often derived from the chemical name 
C)  tends to be somewhat shorter than the drug's chemical name 
D)  all of the above are true 
A)  is also known as the "official" or "nonproprietary" name 
B)  is often derived from the chemical name 
C)  tends to be somewhat shorter than the drug's chemical name 
D)  all of the above are true

Question 8

Prescription use of a drug to treat conditions other than those that the drug was originally approved to treat (off label prescribing)

Accepted Answer

A)  is illegal and punishable by revoking a physician's license 
B)  is legal only if the Center for Disease Control provides written permission to the physician 
C)  is legal only if the drug is not a controlled substance 
D)  is legal and quite common in the United States 
E)  is legal only after the patent for a drug has expired 
A)  is illegal and punishable by revoking a physician's license 
B)  is legal only if the Center for Disease Control provides written permission to the physician 
C)  is legal only if the drug is not a controlled substance 
D)  is legal and quite common in the United States 
E)  is legal only after the patent for a drug has expired

Question 9

Regarding drug development and approval,an "orphan drug" is a drug that is

Accepted Answer

A)  used exclusively in children 
B)  prescribed for conditions other than those approved by the FDA 
C)  given special funding for development because it is used in a small patient population with a relatively rare disease 
D)  available directly to consumers without a prescription 
E)  only available in countries outside the United States 
A)  used exclusively in children 
B)  prescribed for conditions other than those approved by the FDA 
C)  given special funding for development because it is used in a small patient population with a relatively rare disease 
D)  available directly to consumers without a prescription 
E)  only available in countries outside the United States

Question 10

The study of how the body deals with a drug in terms of the way the drug is absorbed,distributed,and eliminated is known as

Accepted Answer

A)  toxicology 
B)  pharmacodynamics 
C)  pharmacy 
D)  pharmacokinetics 
E)  biodynamics 
A)  toxicology 
B)  pharmacodynamics 
C)  pharmacy 
D)  pharmacokinetics 
E)  biodynamics

Question 11

When evaluating drug safety,the dosage that causes 50 percent of subjects to exhibit a specific adverse effect is known as the

Accepted Answer

A)  median therapeutic dose 
B)  median toxic dose 
C)  therapeutic index 
D)  ceiling effect 
E)  threshold dose 
A)  median therapeutic dose 
B)  median toxic dose 
C)  therapeutic index 
D)  ceiling effect 
E)  threshold dose

Question 12

If there is no existing patent for a drug,or if the patent has expired,the same drug may be marketed by separate drug companies under different

Accepted Answer

A)  chemical names 
B)  generic names 
C)  trade names 
D)  nonproprietary names 
E)  organic names 
A)  chemical names 
B)  generic names 
C)  trade names 
D)  nonproprietary names 
E)  organic names

Question 13

The generic form of a drug is considered to be as safe and effective as the original,brand-name product if the generic form _________ as the brand-name drug.

Accepted Answer

A)  has the same type and amount of the active ingredient(s) 
B)  uses the same administration route 
C)  has the same pharmacokinetic profile (drug absorption, plasma levels, and so forth) 
D)  produces the same therapeutic effects 
E)  all the above are true 
A)  has the same type and amount of the active ingredient(s) 
B)  uses the same administration route 
C)  has the same pharmacokinetic profile (drug absorption, plasma levels, and so forth) 
D)  produces the same therapeutic effects 
E)  all the above are true

Question 14

Drugs that can be purchased directly by the consumer without a prescription are also known as

Accepted Answer

A)  nonproprietary medications 
B)  Schedule I controlled substances 
C)  Schedule II controlled substances 
D)  Schedule III controlled substances 
E)  over-the-counter drugs 
A)  nonproprietary medications 
B)  Schedule I controlled substances 
C)  Schedule II controlled substances 
D)  Schedule III controlled substances 
E)  over-the-counter drugs

Exam 1: Basic Principles of Pharmacology

The point at which there is no further increase in the response to a drug even if the dosage continues to be increased is known as the

In general,the greater the value of the _______,the safer the drug is considered to be.

Toxicology is

When two drugs are compared,the drug that requires a lower dosage to produce the same effect as a higher dose of the second drug is said to

During drug testing and approval,the drug is usually tested in a relatively small sample (200 to 300 people)with a specific disease or pathologic condition during

The use of specific drugs to prevent,treat,or diagnose disease is known as

The generic name of a drug

Prescription use of a drug to treat conditions other than those that the drug was originally approved to treat (off label prescribing)

Regarding drug development and approval,an "orphan drug" is a drug that is

The study of how the body deals with a drug in terms of the way the drug is absorbed,distributed,and eliminated is known as

When evaluating drug safety,the dosage that causes 50 percent of subjects to exhibit a specific adverse effect is known as the

If there is no existing patent for a drug,or if the patent has expired,the same drug may be marketed by separate drug companies under different

The generic form of a drug is considered to be as safe and effective as the original,brand-name product if the generic form _________ as the brand-name drug.

Drugs that can be purchased directly by the consumer without a prescription are also known as

Pharmacokinetics IDrug Administration,Absorption,and Distribution

Pharmacokinetics II: Drug Elimination

Drug Receptors

General Principles of Central Nervous System Pharmacology

Sedative Hypnotic and Anti-anxiety Agents

Drugs to Treat Affective Disorders Depression and Bipolar Syndrome

Antipsychotic Drugs

Antiepileptic Drugs

Pharmacologic Management of Parkinson Disease

General Anesthetics

Local Anesthetics

Skeletal Muscle Relaxants

Opioid Analgesics

Non-steroidal Anti Inflammatory Drugs

Pharmacologic Management of Rheumatoid Arthritis and Osteoarthritis

Patient Controlled Analgesia

Introduction to Autonomic Pharmacology

Cholinergic Drugs

Adrenergic Drugs

Antihypertensive Drugs

Treatment of Angina Pectoris

Treatment of Cardiac Arrhythmias

Treatment of Congestive Heart Failure

Treatment of Coagulation Disorders and Hyperlipidemia

Respiratory Drugs

Gastrointestinal Drugs

Introduction to Endocrine Pharmacology

Adrenocorticosteroids

Male and Female Hormones

Thyroid and Parathyroid Drugs: Agents Affecting Bone Mineralization

Pancreatic Hormones and the Treatment of Diabetes Mellitus

Treatment of Infections I: Antibacterial Drugs

Treatment of Infections II: Antiviral Drugs

Treatment of Infections III: Antifungal and Antiparasitic Drugs

Cancer Chemotherapy

Immunomodulating Agents

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