Question 1

Oral bioavailability of opioids is primarily limited by:

Accepted Answer

A)  incomplete absorption. 
B)  first-pass metabolism. 
C)  side effects of nausea and vomiting. 
D)  enterohepatic circulation. 
E)  rapid renal excretion. 
A)  incomplete absorption. 
B)  first-pass metabolism. 
C)  side effects of nausea and vomiting. 
D)  enterohepatic circulation. 
E)  rapid renal excretion.

Question 2

Enkephalins, endorphins, and dynorphins probably function as _____, although their exact function has not been elucidated.

Accepted Answer

A)  prostaglandins 
B)  neurotransmitters 
C)  sedative-hypnotics 
D)  enzymes 
A)  prostaglandins 
B)  neurotransmitters 
C)  sedative-hypnotics 
D)  enzymes

Question 3

Tolerance occurs to the following effects of the opioids except which one?

Accepted Answer

A)  Miosis 
B)  Analgesia 
C)  Respiratory depression 
D)  Nausea 
E)  Histamine release 
A)  Miosis 
B)  Analgesia 
C)  Respiratory depression 
D)  Nausea 
E)  Histamine release

Question 4

Which is the major symptom of opioid overdose?

Accepted Answer

A)  Miosis 
B)  Mydriasis 
C)  Urticaria 
D)  Respiratory depression 
A)  Miosis 
B)  Mydriasis 
C)  Urticaria 
D)  Respiratory depression

Question 5

Morphine has its most potent action on the _____ class of opioid receptors, and pentazocine has its most potent action on the _____ class of opioid receptors.

Accepted Answer

A)  mu; kappa 
B)  mu; delta 
C)  sigma; delta 
D)  kappa; mu 
E)  delta; kappa 
A)  mu; kappa 
B)  mu; delta 
C)  sigma; delta 
D)  kappa; mu 
E)  delta; kappa

Question 6

Opioids are the first choice for the treatment of chronic pain, such as temporomandibular joint and muscle disorders.

Accepted Answer

A) True 
 B)False

Question 7

Which one of the following conditions can be managed or treated with opioids?

Accepted Answer

A)  Diarrhea 
B)  Depression 
C)  Infections 
D)  Hypertension 
A)  Diarrhea 
B)  Depression 
C)  Infections 
D)  Hypertension

Question 8

Which opioid is commonly used as an antitussive?

Accepted Answer

A)  Propoxyphene 
B)  Codeine 
C)  Diphenoxylate 
D)  Pentazocine 
A)  Propoxyphene 
B)  Codeine 
C)  Diphenoxylate 
D)  Pentazocine

Question 9

Which of the following opioids is a metabolite of oxycodone that is three times more potent than oral morphine?

Accepted Answer

A)  Codeine 
B)  Hydrocodone 
C)  Hydromorphone 
D)  Oxymorphone 
A)  Codeine 
B)  Hydrocodone 
C)  Hydromorphone 
D)  Oxymorphone

Question 10

Which opioid analgesic is most likely to produce dysphoria?

Accepted Answer

A)  Meperidine 
B)  Codeine 
C)  Pentazocine 
D)  Oxycodone 
E)  Hydrocodone 
A)  Meperidine 
B)  Codeine 
C)  Pentazocine 
D)  Oxycodone 
E)  Hydrocodone

Question 11

Which of the following opioids is used primarily in the treatment of opioid addicts?

Accepted Answer

A)  Propoxyphene 
B)  Meperidine 
C)  Hydromorphone 
D)  Methadone 
A)  Propoxyphene 
B)  Meperidine 
C)  Hydromorphone 
D)  Methadone

Question 12

Tapentadol is an oral opioid receptor _____ and a _____ reuptake inhibitor.

Accepted Answer

A)  agonist; norepinephrine 
B)  agonist; acetylcholine 
C)  antagonist; norepinephrine 
D)  antagonist; acetylcholine 
A)  agonist; norepinephrine 
B)  agonist; acetylcholine 
C)  antagonist; norepinephrine 
D)  antagonist; acetylcholine

Question 13

A patient presents with itching and urticaria after codeine administration. This response most likely represents a:

Accepted Answer

A)  pharmacologic action of codeine. 
B)  hypersensitivity reaction to codeine. 
C)  placebo effect from receiving codeine. 
D)  reaction unrelated to codeine administration. 
A)  pharmacologic action of codeine. 
B)  hypersensitivity reaction to codeine. 
C)  placebo effect from receiving codeine. 
D)  reaction unrelated to codeine administration.

Question 14

Which of the following types of pain medications is the best choice for management of most dental pain?

Accepted Answer

A)  Antidepressants 
B)  Nonsteroidal anti-inflammatory drugs (NSAIDs) 
C)  Aspirin 
D)  Acetaminophen 
A)  Antidepressants 
B)  Nonsteroidal anti-inflammatory drugs (NSAIDs) 
C)  Aspirin 
D)  Acetaminophen

Question 15

Which of the following drugs can be used to treat heroin addiction?

Accepted Answer

A)  Hydromorphone 
B)  Methadone 
C)  Naltrexone 
D)  Both a and c 
E)  Both b and c 
A)  Hydromorphone 
B)  Methadone 
C)  Naltrexone 
D)  Both a and c 
E)  Both b and c

Exam 6: Opioid (Narcotic)Analgesics and Antagonists

Oral bioavailability of opioids is primarily limited by:

Enkephalins, endorphins, and dynorphins probably function as _____, although their exact function has not been elucidated.

Tolerance occurs to the following effects of the opioids except which one?

Which is the major symptom of opioid overdose?

Morphine has its most potent action on the _____ class of opioid receptors, and pentazocine has its most potent action on the _____ class of opioid receptors.

Opioids are the first choice for the treatment of chronic pain, such as temporomandibular joint and muscle disorders.

Which one of the following conditions can be managed or treated with opioids?

Which opioid is commonly used as an antitussive?

Which of the following opioids is a metabolite of oxycodone that is three times more potent than oral morphine?

Which opioid analgesic is most likely to produce dysphoria?

Which of the following opioids is used primarily in the treatment of opioid addicts?

Tapentadol is an oral opioid receptor _____ and a _____ reuptake inhibitor.

A patient presents with itching and urticaria after codeine administration. This response most likely represents a:

Which of the following types of pain medications is the best choice for management of most dental pain?

Which of the following drugs can be used to treat heroin addiction?

Information Sources, Regulatory Agencies, Drug Legislation, and Prescription Writing

Drug Action and Handling

Adverse Reactions

Autonomic Drugs

Nonopioid (Nonnarcotic)Analgesics

Antiinfective Agents

Antifungal and Antiviral Agents

Local Anesthetics

General Anesthetics

Antianxiety Agents

Oral Conditions and Their Treatment

Hygiene-Related Oral Disorders

Drugs for the Treatment of Cardiovascular Disease

Drugs for the Treatment of Gastrointestinal Disorders

Drugs for the Treatment of Seizure Disorders

Drugs for the Treatment of Central Nervous System Disorders

Adrenocorticosteroids

Drugs for the Treatment of Respiratory Disorders

Drugs for the Treatment of Allergic Rhinitis

Drugs for the Treatment of Diabetes Mellitus

Drugs for the Treatment of Other Endocrine Disorders

Antineoplastic Drugs

Emergency Drugs

Pregnancy and Breast Feeding

Drug Abuse

Natural/Herbal Products and Dietary Supplements

Filters

Morphine has its most potent action on the _ class of opioid receptors, and pentazocine has its most potent action on the _ class of opioid receptors.

Tapentadol is an oral opioid receptor _ and a _ reuptake inhibitor.