Question 1

Which of the following receptor types causes the formation of second messengers?

Accepted Answer

A) Ion channel linked receptors 
B) G-protein linked receptors 
C) Kinase linked receptors 
D) DNA coupled receptors 
A) Ion channel linked receptors 
B) G-protein linked receptors 
C) Kinase linked receptors 
D) DNA coupled receptors B

Question 2

If two drugs antagonize each other while acting on different receptor sites,then this antagonism is referred to as _________.

Accepted Answer

A) physiological antagonism 
B) competitive antagonism 
C) chemical antagonism 
D) pharmacological antagonism 
A) physiological antagonism 
B) competitive antagonism 
C) chemical antagonism 
D) pharmacological antagonism A

Question 3

Antagonists _________.

Accepted Answer

A) block the receptor by changing its conformation into an unresponsive state 
B) can always be displaced by an agonist 
C) block endogenous compounds from stimulating the receptor 
D) after chronic use can decrease the number of receptors 
A) block the receptor by changing its conformation into an unresponsive state 
B) can always be displaced by an agonist 
C) block endogenous compounds from stimulating the receptor 
D) after chronic use can decrease the number of receptors C

Question 4

With a dose-response curve,the Kd ______________.

Accepted Answer

A) is the dose necessary to achieve Emax 
B) is the dose at half the Emax 
C) determines efficacy 
D) is equivalent to the toxic index 
A) is the dose necessary to achieve Emax 
B) is the dose at half the Emax 
C) determines efficacy 
D) is equivalent to the toxic index

Question 5

The correct sequence of the second messenger forming elements is _________.

Accepted Answer

A) drug, receptor, enzyme, G-protein, second messenger 
B) drug, receptor, G-protein, enzyme, second messenger 
C) drug, G-protein, receptor, enzyme, second messenger 
D) drug, enzyme, receptor, G protein, second messenger 
A) drug, receptor, enzyme, G-protein, second messenger 
B) drug, receptor, G-protein, enzyme, second messenger 
C) drug, G-protein, receptor, enzyme, second messenger 
D) drug, enzyme, receptor, G protein, second messenger

Question 6

Chemical groups or sites on the cell surface with which drugs combine to produce effects are _________.

Accepted Answer

A) antagonist 
B) agonists 
C) molecular targets (receptors) 
D) placebos 
A) antagonist 
B) agonists 
C) molecular targets (receptors) 
D) placebos

Question 7

Agonists _________.

Accepted Answer

A) bind selectively to a receptor but do not change its conformation 
B) can be divided into reversible and irreversible agonists 
C) after chronic use can decrease the number of receptors 
D) All of the above 
A) bind selectively to a receptor but do not change its conformation 
B) can be divided into reversible and irreversible agonists 
C) after chronic use can decrease the number of receptors 
D) All of the above

Question 8

The fastest response after drug stimulation of a receptor is observed with _________.

Accepted Answer

A) ligand gated receptors 
B) G-protein coupled receptors 
C) kinase linked receptors 
D) DNA coupled receptors 
A) ligand gated receptors 
B) G-protein coupled receptors 
C) kinase linked receptors 
D) DNA coupled receptors

Question 9

If the dose-response curve (increasing doses vs.physiological effects)of an agonist is plotted and then another curve is obtained when an antagonist has been added to the agonist,then the second curve is moved _________.

Accepted Answer

A) parallel to the left in case of a competitive antagonist 
B) parallel to the right in case of a competitive antagonist 
C) parallel to the left in case of a non-competitive antagonist 
D) parallel to the right in case of a non-competitive antagonist 
A) parallel to the left in case of a competitive antagonist 
B) parallel to the right in case of a competitive antagonist 
C) parallel to the left in case of a non-competitive antagonist 
D) parallel to the right in case of a non-competitive antagonist

Which of the following receptor types causes the formation of second messengers?

If two drugs antagonize each other while acting on different receptor sites,then this antagonism is referred to as _________.

Antagonists _________.

With a dose-response curve,the Kd ______________.

The correct sequence of the second messenger forming elements is _________.

Chemical groups or sites on the cell surface with which drugs combine to produce effects are _________.

Agonists _________.

The fastest response after drug stimulation of a receptor is observed with _________.

If the dose-response curve (increasing doses vs.physiological effects)of an agonist is plotted and then another curve is obtained when an antagonist has been added to the agonist,then the second curve is moved _________.

Introduction

Pharmacokinetics and Drug Dosing

Adverse Drug Reactions

Drugs Acting on the Autonomic Nervous System

Antihypertensive

Drug Therapy of Coronary Atherosclerosis and Its Repercussions

Drug Therapy for Congestive Heart Failure and Cardiac Arrhythmias

Drug Therapy for Pulmonary Disorders

Anesthetic Agents

Drugs for the Treatment of Pain and Inflammation

Drug Treatment for Arthritis-Related Conditions

Selective Topics in Endocrine Pharmacology

Drug Treatment for Osteoporosis and Diabetes

Drugs for Epilepsy and Attention Deficit/Hyperactivity Disorder

Antispasticity Medications and Skeletal Muscle Relaxants

Pharmacologic Management of Degenerative Neurologic Disorders

Drug Treatment for Depression and Anxiety

Drug Treatment for Schizophrenia and Bipolar Illness

Antimicrobial Agents

Antiviral Agents and Selected Drugs for Fungal Infections

Cytotoxic Agents and Immune Modulation

Drugs for Gastrointestinal Disorders

Vitamins and Minerals

Topical Drugs and Treatments Used in Wound Management

Complementary and Alternative Medicine in Pharmacology

Drugs of Abuse: Anabolic Steroids and Other Doping Agents

Filters

Exam 2: Pharmacodynamics: Mechanism of Action

Which of the following receptor types causes the formation of second messengers?

If two drugs antagonize each other while acting on different receptor sites,then this antagonism is referred to as _________.

Antagonists _________.

With a dose-response curve,the Kd ______________.

The correct sequence of the second messenger forming elements is _________.

Chemical groups or sites on the cell surface with which drugs combine to produce effects are _________.

Agonists _________.

The fastest response after drug stimulation of a receptor is observed with _________.

If the dose-response curve (increasing doses vs.physiological effects)of an agonist is plotted and then another curve is obtained when an antagonist has been added to the agonist,then the second curve is moved _________.

Introduction

Pharmacokinetics and Drug Dosing

Adverse Drug Reactions

Drugs Acting on the Autonomic Nervous System

Antihypertensive

Drug Therapy of Coronary Atherosclerosis and Its Repercussions

Drug Therapy for Congestive Heart Failure and Cardiac Arrhythmias

Drug Therapy for Pulmonary Disorders

Anesthetic Agents

Drugs for the Treatment of Pain and Inflammation

Drug Treatment for Arthritis-Related Conditions

Selective Topics in Endocrine Pharmacology

Drug Treatment for Osteoporosis and Diabetes

Drugs for Epilepsy and Attention Deficit/Hyperactivity Disorder

Antispasticity Medications and Skeletal Muscle Relaxants

Pharmacologic Management of Degenerative Neurologic Disorders

Drug Treatment for Depression and Anxiety

Drug Treatment for Schizophrenia and Bipolar Illness

Antimicrobial Agents

Antiviral Agents and Selected Drugs for Fungal Infections

Cytotoxic Agents and Immune Modulation

Drugs for Gastrointestinal Disorders

Vitamins and Minerals

Topical Drugs and Treatments Used in Wound Management

Complementary and Alternative Medicine in Pharmacology

Drugs of Abuse: Anabolic Steroids and Other Doping Agents

Filters