Question 1

The actions of the parasympathetic nervous system include which of the following?

Accepted Answer

A) Increased muscular motility and tone of the GI tract 
B) Increased contractility of the heart 
C) Triggering of the "fight-or-flight" response 
D) Urinary retention 
A) Increased muscular motility and tone of the GI tract 
B) Increased contractility of the heart 
C) Triggering of the "fight-or-flight" response 
D) Urinary retention A

Question 2

α-Adrenoceptors show the strongest response to which of the following agonists?

Accepted Answer

A) α₂ agonists 
B) Catcholamines 
C) α agonists 
D) α₂ blockers 
A) α₂ agonists 
B) Catcholamines 
C) α agonists 
D) α₂ blockers B

Question 3

Beta-blockers ______________.

Accepted Answer

A) increase fluid influx into the eye and are contraindicated in glaucoma 
B) cause some vasodilatation and hot feet and hands 
C) decrease heart rate and mask the onset of a hypoglycemic episode 
D) are contraindicated in patients with angina pectoris 
A) increase fluid influx into the eye and are contraindicated in glaucoma 
B) cause some vasodilatation and hot feet and hands 
C) decrease heart rate and mask the onset of a hypoglycemic episode 
D) are contraindicated in patients with angina pectoris C

Question 4

Alpha agonists ______________.

Accepted Answer

A) constrict the sphincter muscle of the iris leading to miosis 
B) constrict blood vessels leading to decreased blood pressure 
C) constrict the sphincter of the bladder leading to urinary retention 
D) stimulate GI-tract muscles leading to diarrhea 
A) constrict the sphincter muscle of the iris leading to miosis 
B) constrict blood vessels leading to decreased blood pressure 
C) constrict the sphincter of the bladder leading to urinary retention 
D) stimulate GI-tract muscles leading to diarrhea

Question 5

Anticholinergic drugs cause______________.

Accepted Answer

A) dry mouth 
B) diarrhea 
C) bradycardia 
D) frequent urination 
A) dry mouth 
B) diarrhea 
C) bradycardia 
D) frequent urination

Question 6

Muscarinic receptors are located at all of the following except the ______________.

Accepted Answer

A) blood vessels 
B) bladder 
C) bronchi 
D) adrenal medulla 
A) blood vessels 
B) bladder 
C) bronchi 
D) adrenal medulla

Question 7

The type of receptor found across autonomic ganglia in both the sympathetic and parasympathetic nervous system is ________________ receptor.

Accepted Answer

A) Nicotinic acetylcholine 
B) Muscarinic acetylcholine 
C) Adrenergic norepinephrine 
D) Adrenergic epinephrine 
A) Nicotinic acetylcholine 
B) Muscarinic acetylcholine 
C) Adrenergic norepinephrine 
D) Adrenergic epinephrine

Question 8

Match between columns
                        Premises: Calcium channel blockers
ACE inhibitor 
Diuretic
α2 Agonist
β-Blocker

Accepted Answer

The Answer of Produces vasodilation by inhibiting calcium flow and is...

Question 9

Therapeutic actions of β-blockers include __________.

Accepted Answer

A) bronchoconstriction 
B) reflex peripheral vasoconstriction 
C) decreased renin release 
D) increased sodium retention 
A) bronchoconstriction 
B) reflex peripheral vasoconstriction 
C) decreased renin release 
D) increased sodium retention

Question 10

Noradrenergic neurotransmission involves ______________.

Accepted Answer

A) synthesis of norepinephrine (N
E)  by monoamine oxidase or MAO 
B) synthesis of NE from epinephrine 
C) interaction with adrenergic gamma and delta receptors 
D) termination of action which is usually via re-uptake into the neuron 
A) synthesis of norepinephrine (N
E)  by monoamine oxidase or MAO 
B) synthesis of NE from epinephrine 
C) interaction with adrenergic gamma and delta receptors 
D) termination of action which is usually via re-uptake into the neuron

Question 11

Anticholinesterases ______________.

Accepted Answer

A) are used to treat myasthenia gravis 
B) cause constipation 
C) dilate bronchi 
D) cause muscular spasm leading to death during an overdose 
A) are used to treat myasthenia gravis 
B) cause constipation 
C) dilate bronchi 
D) cause muscular spasm leading to death during an overdose

Question 12

An overactive bladder is most likely to be treated with a(n)______________.

Accepted Answer

A) alpha antagonist 
B) beta antagonist 
C) muscarinic agonist 
D) muscarinic antagonist 
A) alpha antagonist 
B) beta antagonist 
C) muscarinic agonist 
D) muscarinic antagonist

Question 13

A drug causing mydriasis,an increase in blood pressure and which is being used as a nasal decongesting drug is a(n)______________.

Accepted Answer

A) alpha agonist 
B) alpha antagonist 
C) beta agonist 
D) beta antagonist 
A) alpha agonist 
B) alpha antagonist 
C) beta agonist 
D) beta antagonist

Question 14

Cholinergic neurotransmission involves ______________.

Accepted Answer

A) synthesis of acetylcholine (ACh) by acetyl cholinesterase 
B) release of acetylcholine (ACh) from nerve terminal by action of Mg ions 
C) interaction of ACh with muscarinic or nicotinic receptors 
D) termination of Ach action by active re-uptake 
A) synthesis of acetylcholine (ACh) by acetyl cholinesterase 
B) release of acetylcholine (ACh) from nerve terminal by action of Mg ions 
C) interaction of ACh with muscarinic or nicotinic receptors 
D) termination of Ach action by active re-uptake

Question 15

Beta 2 agonists ______________.

Accepted Answer

A) constrict blood vessels and causes an increase in blood pressure 
B) relax bronchi and cause increased airflow 
C) stimulate the pregnant uterus leading to premature contractions 
D) affect glucose metabolism and decreases blood glucose levels 
A) constrict blood vessels and causes an increase in blood pressure 
B) relax bronchi and cause increased airflow 
C) stimulate the pregnant uterus leading to premature contractions 
D) affect glucose metabolism and decreases blood glucose levels

Question 16

Elderly individuals are more prone to ______________.

Accepted Answer

A) diarrhea caused by drugs with anticholinergic activities 
B) bradycardia caused by drugs with muscarinic activities 
C) excitation caused by drugs with anticholinergic activities 
D) insomnia caused by anticholinesterases 
A) diarrhea caused by drugs with anticholinergic activities 
B) bradycardia caused by drugs with muscarinic activities 
C) excitation caused by drugs with anticholinergic activities 
D) insomnia caused by anticholinesterases

Question 17

Alpha receptors are located at all of the following except the______________.

Accepted Answer

A) blood vessels 
B) GI tract 
C) bronchi 
D) iris of the eye 
A) blood vessels 
B) GI tract 
C) bronchi 
D) iris of the eye

Question 18

The actions of the sympathetic nervous system include which of the following?

Accepted Answer

A) Constriction of the trachea and bronchioles 
B) Pupil dilation 
C) Decreased heart rate 
D) Contraction of the bladder wall 
A) Constriction of the trachea and bronchioles 
B) Pupil dilation 
C) Decreased heart rate 
D) Contraction of the bladder wall

Question 19

Alpha blockers ______________.

Accepted Answer

A) dilate blood vessels and are used to treat hypertension 
B) dilate the pupil and cause photophobia 
C) constrict nasal blood vessels and cause a runny nose 
D) inhibit heart contractions and cause bradycardia 
A) dilate blood vessels and are used to treat hypertension 
B) dilate the pupil and cause photophobia 
C) constrict nasal blood vessels and cause a runny nose 
D) inhibit heart contractions and cause bradycardia

Question 20

α-Adrenergic-blocking agents are responsible for which of the following?

Accepted Answer

A) Increased blood pressure 
B) Decreased sympathetic tone of blood vessels 
C) Reflex bradycardia 
D) Asthma 
A) Increased blood pressure 
B) Decreased sympathetic tone of blood vessels 
C) Reflex bradycardia 
D) Asthma

Exam 5: Drugs Acting on the Autonomic Nervous System

The actions of the parasympathetic nervous system include which of the following?

α-Adrenoceptors show the strongest response to which of the following agonists?

Beta-blockers ______________.

Alpha agonists ______________.

Anticholinergic drugs cause______________.

Muscarinic receptors are located at all of the following except the ______________.

The type of receptor found across autonomic ganglia in both the sympathetic and parasympathetic nervous system is ________________ receptor.

Therapeutic actions of β-blockers include __________.

Noradrenergic neurotransmission involves ______________.

Anticholinesterases ______________.

An overactive bladder is most likely to be treated with a(n)______________.

A drug causing mydriasis,an increase in blood pressure and which is being used as a nasal decongesting drug is a(n)______________.

Cholinergic neurotransmission involves ______________.

Beta 2 agonists ______________.

Elderly individuals are more prone to ______________.

Alpha receptors are located at all of the following except the______________.

The actions of the sympathetic nervous system include which of the following?

Alpha blockers ______________.

α-Adrenergic-blocking agents are responsible for which of the following?

Introduction

Pharmacodynamics: Mechanism of Action

Pharmacokinetics and Drug Dosing

Adverse Drug Reactions

Antihypertensive

Drug Therapy of Coronary Atherosclerosis and Its Repercussions

Drug Therapy for Congestive Heart Failure and Cardiac Arrhythmias

Drug Therapy for Pulmonary Disorders

Anesthetic Agents

Drugs for the Treatment of Pain and Inflammation

Drug Treatment for Arthritis-Related Conditions

Selective Topics in Endocrine Pharmacology

Drug Treatment for Osteoporosis and Diabetes

Drugs for Epilepsy and Attention Deficit/Hyperactivity Disorder

Antispasticity Medications and Skeletal Muscle Relaxants

Pharmacologic Management of Degenerative Neurologic Disorders

Drug Treatment for Depression and Anxiety

Drug Treatment for Schizophrenia and Bipolar Illness

Antimicrobial Agents

Antiviral Agents and Selected Drugs for Fungal Infections

Cytotoxic Agents and Immune Modulation

Drugs for Gastrointestinal Disorders

Vitamins and Minerals

Topical Drugs and Treatments Used in Wound Management

Complementary and Alternative Medicine in Pharmacology

Drugs of Abuse: Anabolic Steroids and Other Doping Agents

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