Question 1

Inflamed bronchi can become hyper-active in response to all of the following except ______________.

Accepted Answer

A) exercise 
B) cold, dry air 
C) allergens 
D) All of the above 
A) exercise 
B) cold, dry air 
C) allergens 
D) All of the above B

Question 2

Endogenous substances which cause bronchoconstriction include all of the following except
______________.

Accepted Answer

A) acetylcholine 
B) histamine 
C) epinephrine 
D) leukotrienes 
A) acetylcholine 
B) histamine 
C) epinephrine 
D) leukotrienes C

Question 3

Alpha agonists used to treat rhinitis ______________.

Accepted Answer

A) dilate blood vessels and decrease vessel permeability 
B) can cause a rebound effect 
C) can cause orthostatic hypotension 
D) are the only agents which have been shown to be effective in rhinitis 
A) dilate blood vessels and decrease vessel permeability 
B) can cause a rebound effect 
C) can cause orthostatic hypotension 
D) are the only agents which have been shown to be effective in rhinitis B

Question 4

Exercise induced asthma ______________.

Accepted Answer

A) is a relative rare occurrence 
B) will get worse the more a person exercises 
C) can be prevented by using a short-acting beta 2 agonist 15-60 minutes before exercise 
D) has been shown not to be influenced by warm-up procedures before exercise 
A) is a relative rare occurrence 
B) will get worse the more a person exercises 
C) can be prevented by using a short-acting beta 2 agonist 15-60 minutes before exercise 
D) has been shown not to be influenced by warm-up procedures before exercise

Question 5

Cromolyn and nedocromil ______________.

Accepted Answer

A) inhibit the release of histamine and leukotrienes from mast cells 
B) cause bronchodilation by stimulating H1 receptors 
C) can quickly terminate an asthmatic attack 
D) are seldom used because of their adverse reactions 
A) inhibit the release of histamine and leukotrienes from mast cells 
B) cause bronchodilation by stimulating H1 receptors 
C) can quickly terminate an asthmatic attack 
D) are seldom used because of their adverse reactions

Question 6

Status asthmaticus ______________.

Accepted Answer

A) can be caused by too frequent applications of leukotriene antagonists 
B) can be precipitated by the formation of airflow impairing mucus plugs 
C) is usually self-limiting 
D) All of the above 
A) can be caused by too frequent applications of leukotriene antagonists 
B) can be precipitated by the formation of airflow impairing mucus plugs 
C) is usually self-limiting 
D) All of the above

Question 7

Which of the following drugs are considered short-term relievers for asthma?

Accepted Answer

A) β₂ agonists 
B) Oral steroids 
C) Inhaled steroids 
D) Leukotriene antagonists 
A) β₂ agonists 
B) Oral steroids 
C) Inhaled steroids 
D) Leukotriene antagonists

Question 8

Which of the following drugs are used to lessen the symptoms of cystic fibrosis?

Accepted Answer

A) Mucolytic agents 
B) β-Blockers 
C) Calcium channel blockers 
D) Agonists 
A) Mucolytic agents 
B) β-Blockers 
C) Calcium channel blockers 
D) Agonists

Question 9

Which of the following statements is false regarding beta 2 agonists used to treat asthma?

Accepted Answer

A) They stimulate bronchial beta 2 receptors. 
B) They are divided into short- and long-acting drugs. 
C) Used long term they can cause tolerance. 
D) Given orally they are more effective than those used by inhalation. 
A) They stimulate bronchial beta 2 receptors. 
B) They are divided into short- and long-acting drugs. 
C) Used long term they can cause tolerance. 
D) Given orally they are more effective than those used by inhalation.

Question 10

You are treating a 67-year-old male with a diagnosis of chronic obstructive pulmonary disease.In addition,he has a history of hypertension and congestive heart disease.Which of the following drugs would be contraindicated?

Accepted Answer

A) Diuretic 
B) ACE inhibitor 
C) ACE receptor blocker 
D) Inhaled steroids 
A) Diuretic 
B) ACE inhibitor 
C) ACE receptor blocker 
D) Inhaled steroids

Question 11

Which one of the following is the most appropriate drug to reverse her acute bronchoconstriction?

Accepted Answer

A) Inhaled α₂ agonists 
B) Inhaled anticholinergics 
C) Inhaled mast cell stabilizers 
D) Oral steroids 
A) Inhaled α₂ agonists 
B) Inhaled anticholinergics 
C) Inhaled mast cell stabilizers 
D) Oral steroids

Question 12

You are exercising a teenage girl who has a history of asthma.During the course of her therapy session she begins to complain of cough,dyspnea,and wheezing.Unfortunately she has left her inhaler at home.Vital signs include RR,42 breaths/minutes; pulse rate,120 bpm; and blood pressure,150/70 mm Hg.What is the most immediate course of action?

Accepted Answer

A) Send her home. 
B) Have her breathe into a bag. 
C) Call her home to see if someone can bring in her inhaler. 
D) Call 911. 
A) Send her home. 
B) Have her breathe into a bag. 
C) Call her home to see if someone can bring in her inhaler. 
D) Call 911.

Question 13

Leukotriene affecting drugs ______________.

Accepted Answer

A) can be divided into synthesis inhibitors and receptor blockers 
B) are only used as monotherapy 
C) are contraindicated in children 
D) are highly effective but carry many adverse reactions 
A) can be divided into synthesis inhibitors and receptor blockers 
B) are only used as monotherapy 
C) are contraindicated in children 
D) are highly effective but carry many adverse reactions

Question 14

Further questioning of this patient revealed that she suffers at least four asthmatic episodes per week.Which of the following drugs would be most useful in providing a sustained resolution of her symptoms?

Accepted Answer

A) IV steriods 
B) Leukotriene antagonists 
C) Inhaled α₂ agonists 
D) Coffee 
A) IV steriods 
B) Leukotriene antagonists 
C) Inhaled α₂ agonists 
D) Coffee

Question 15

Chronic obstructive pulmonary disease is treated with all of the following drugs except ______________.

Accepted Answer

A) corticosteroids 
B) beta 2 agonists 
C) muscarinic antagonists 
D) antihistamines 
A) corticosteroids 
B) beta 2 agonists 
C) muscarinic antagonists 
D) antihistamines

Question 16

Theophylline ______________.

Accepted Answer

A) is the generic name for caffeine 
B) blocks muscarinic receptors causing bronchodilation 
C) is often the oral drug of first choice 
D) can cause a number of adverse drug interactions 
A) is the generic name for caffeine 
B) blocks muscarinic receptors causing bronchodilation 
C) is often the oral drug of first choice 
D) can cause a number of adverse drug interactions

Question 17

Measured dose inhalation devices must be used properly.Which of the following is false?

Accepted Answer

A) They should be kept at room temperature and shaken before use. 
B) They should be held about 2-4 inches from the mouth (unless a spacer is provided). 
C) The patient should exhale before use. 
D) The patient should activate the device while inhaling slowly for 2-5 seconds. 
A) They should be kept at room temperature and shaken before use. 
B) They should be held about 2-4 inches from the mouth (unless a spacer is provided). 
C) The patient should exhale before use. 
D) The patient should activate the device while inhaling slowly for 2-5 seconds.

Exam 9: Drug Therapy for Pulmonary Disorders

Inflamed bronchi can become hyper-active in response to all of the following except ______________.

Endogenous substances which cause bronchoconstriction include all of the following except ______________.

Alpha agonists used to treat rhinitis ______________.

Exercise induced asthma ______________.

Cromolyn and nedocromil ______________.

Status asthmaticus ______________.

Which of the following drugs are considered short-term relievers for asthma?

Which of the following drugs are used to lessen the symptoms of cystic fibrosis?

Which of the following statements is false regarding beta 2 agonists used to treat asthma?

You are treating a 67-year-old male with a diagnosis of chronic obstructive pulmonary disease.In addition,he has a history of hypertension and congestive heart disease.Which of the following drugs would be contraindicated?

Which one of the following is the most appropriate drug to reverse her acute bronchoconstriction?

Leukotriene affecting drugs ______________.

Further questioning of this patient revealed that she suffers at least four asthmatic episodes per week.Which of the following drugs would be most useful in providing a sustained resolution of her symptoms?

Chronic obstructive pulmonary disease is treated with all of the following drugs except ______________.

Theophylline ______________.

Measured dose inhalation devices must be used properly.Which of the following is false?

Introduction

Pharmacodynamics: Mechanism of Action

Pharmacokinetics and Drug Dosing

Adverse Drug Reactions

Drugs Acting on the Autonomic Nervous System

Antihypertensive

Drug Therapy of Coronary Atherosclerosis and Its Repercussions

Drug Therapy for Congestive Heart Failure and Cardiac Arrhythmias

Anesthetic Agents

Drugs for the Treatment of Pain and Inflammation

Drug Treatment for Arthritis-Related Conditions

Selective Topics in Endocrine Pharmacology

Drug Treatment for Osteoporosis and Diabetes

Drugs for Epilepsy and Attention Deficit/Hyperactivity Disorder

Antispasticity Medications and Skeletal Muscle Relaxants

Pharmacologic Management of Degenerative Neurologic Disorders

Drug Treatment for Depression and Anxiety

Drug Treatment for Schizophrenia and Bipolar Illness

Antimicrobial Agents

Antiviral Agents and Selected Drugs for Fungal Infections

Cytotoxic Agents and Immune Modulation

Drugs for Gastrointestinal Disorders

Vitamins and Minerals

Topical Drugs and Treatments Used in Wound Management

Complementary and Alternative Medicine in Pharmacology

Drugs of Abuse: Anabolic Steroids and Other Doping Agents

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