Question 1

Which of the following statements is false?

Accepted Answer

A) Atenolol and metoprolol are relatively selective beta 2 blockers. 
B) Pindolol inhibits beta receptors only when sympathetic activity is low. 
C) Abrupt withdrawal of beta-blockers can trigger dangerous dysrhythmias. 
D) Beta-blockers cause irritation and insomnia. 
A) Atenolol and metoprolol are relatively selective beta 2 blockers. 
B) Pindolol inhibits beta receptors only when sympathetic activity is low. 
C) Abrupt withdrawal of beta-blockers can trigger dangerous dysrhythmias. 
D) Beta-blockers cause irritation and insomnia. D

Question 2

To maintain normal blood pressure,the body has reflex mechanisms available.Which of the following reflex mechanisms helps to maintain normal blood pressure?

Accepted Answer

A) Increased pressure increases heart rate 
B) Increased pressure reduces heart rate 
C) Decreased blood pressure decreases heart rate 
D) Decreased blood pressure decreases peripheral resistance 
A) Increased pressure increases heart rate 
B) Increased pressure reduces heart rate 
C) Decreased blood pressure decreases heart rate 
D) Decreased blood pressure decreases peripheral resistance B

Question 3

Match between columns
                        Premises: β-blocker
Thiazide diuretics
Calcium channel blocker
HMG-CoA reductase inhibitor
ACE Inhibitor

Accepted Answer

The Answer of Dry cough, hyperkalemia, hypotension and Hypotension, constipation, is...

Question 4

An asymptomatic female athlete with mild hypertension (150/95 mm Hg)should be treated with which of the following regimens or drugs?

Accepted Answer

A) Nonspecific β-blocker 
B) Calcium channel blocker 
C) ACE receptor blocker 
D) α₂ Agonist 
A) Nonspecific β-blocker 
B) Calcium channel blocker 
C) ACE receptor blocker 
D) α₂ Agonist

Question 5

ACE inhibitors ___________.

Accepted Answer

A) are usually the drugs of last resort 
B) cause hypokalemia 
C) can cause a disabling cough 
D) include drugs like losartan and olmesartan 
A) are usually the drugs of last resort 
B) cause hypokalemia 
C) can cause a disabling cough 
D) include drugs like losartan and olmesartan

Question 6

Nonselective β-blockers can be used to treat hypertension and which of the following?

Accepted Answer

A) Superventricular arrhythmia 
B) Heart block 
C) COPD 
D) Heart failure 
A) Superventricular arrhythmia 
B) Heart block 
C) COPD 
D) Heart failure

Question 7

Angiotensin II ___________.

Accepted Answer

A) is formed from renin 
B) has special receptors on blood vessels 
C) inhibits aldosterone release 
D) all are correct 
A) is formed from renin 
B) has special receptors on blood vessels 
C) inhibits aldosterone release 
D) all are correct

Question 8

Which of the following is not a vasodilator?

Accepted Answer

A) Nitric oxide 
B) Prostaglandins, specifically PGI₂ 
C) Angiotensin II 
D) C natriuretic peptides 
A) Nitric oxide 
B) Prostaglandins, specifically PGI₂ 
C) Angiotensin II 
D) C natriuretic peptides

Question 9

Mean arterial pressure depends on ___________.

Accepted Answer

A) heart rate 
B) stroke volume 
C) peripheral resistance 
D) All of the above 
A) heart rate 
B) stroke volume 
C) peripheral resistance 
D) All of the above

Question 10

Why would a thiazide diuretic and a K⁺-sparing diuretic be administered together?

Accepted Answer

A) This combination prevents hypokalemia. 
B) This combination prevents dehydration. 
C) These drugs are effective at increasing glomerular filtration rate when given together. 
D) Moderate doses of two diuretics are more effective than a large dose of one. 
A) This combination prevents hypokalemia. 
B) This combination prevents dehydration. 
C) These drugs are effective at increasing glomerular filtration rate when given together. 
D) Moderate doses of two diuretics are more effective than a large dose of one.

Question 11

You are working with a patient who is on β-blockers.The resting heart rate is 80 bpm,and the resting BP is 135/90 mm Hg.Which of the following is an acceptable response to exercise?

Accepted Answer

A) Exercise heart rate = 140 bpm, BP =140/60 mm Hg 
B) Exercise heart rate = 100 bpm, BP = 145/85 mm Hg 
C) Exercise heart rate = 80 bpm, BP = 140/120 mm Hg 
D) Exercise heart rate = 70 bpm, BP = 100/60 mm Hg 
A) Exercise heart rate = 140 bpm, BP =140/60 mm Hg 
B) Exercise heart rate = 100 bpm, BP = 145/85 mm Hg 
C) Exercise heart rate = 80 bpm, BP = 140/120 mm Hg 
D) Exercise heart rate = 70 bpm, BP = 100/60 mm Hg

Question 12

The mechanism of action of calcium channel blockers is to ________________.

Accepted Answer

A) force the calcium out of the myocardial cells 
B) block the entry of calcium into the myocardial cells 
C) constrict blood vessels 
D) act as an autonomic drug 
A) force the calcium out of the myocardial cells 
B) block the entry of calcium into the myocardial cells 
C) constrict blood vessels 
D) act as an autonomic drug

Question 13

Match between columns
                        Premises: α-Blockers
Antiarrhythmic
Oral anticoagulants
Thrombolytics

Accepted Answer

The Answer of Orthostatic hypotension, reflex tachycardia, dizziness and Aggravation is...

Question 14

Vasoconstriction would be desired when it is necessary to ___________.

Accepted Answer

A) lower blood pressure 
B) raise blood pressure 
C) stop cardiac arrhythmias 
D) prolong clotting time 
A) lower blood pressure 
B) raise blood pressure 
C) stop cardiac arrhythmias 
D) prolong clotting time

Question 15

Therapeutic concerns with the use of diuretics include ___________.

Accepted Answer

A) dehydration 
B) muscle weakness 
C) hyperglycemia 
D) All of the above 
A) dehydration 
B) muscle weakness 
C) hyperglycemia 
D) All of the above

Question 16

Therapeutic actions of β-blockers include __________.

Accepted Answer

A) bronchoconstriction 
B) reflex peripheral vasoconstriction 
C) decreased renin release 
D) increased sodium retention 
A) bronchoconstriction 
B) reflex peripheral vasoconstriction 
C) decreased renin release 
D) increased sodium retention

Question 17

You are treating a patient with hypertension who is taking a β-blocker.Information regarding safe dosing and exercise include which of the following?

Accepted Answer

A) A patient who experiences dizziness during exercise should stop the drug for 2 days. 
B) Increased consumption of broccoli is required to prevent bleeding during exercise with this drug. 
C) A heart rate under 60 bpm requires skipping a dose and contacting the physician. 
D) To combat the fatiguing effect of the drug during exercise, drink 2 cups of caffeinated coffee before therapy. 
A) A patient who experiences dizziness during exercise should stop the drug for 2 days. 
B) Increased consumption of broccoli is required to prevent bleeding during exercise with this drug. 
C) A heart rate under 60 bpm requires skipping a dose and contacting the physician. 
D) To combat the fatiguing effect of the drug during exercise, drink 2 cups of caffeinated coffee before therapy.

Question 18

Which of the following statements is false?

Accepted Answer

A) All antihypertensive drugs can cause orthostatic hypotension. 
B) Thiazide diuretics have been shown to increase the risk of diabetes. 
C) A minimum target increase in heart rate during exercise should be 50 beats/min in patients receiving a beta-blocker. 
D) Environmental temperature can affect ADRs of antihypertensive drugs. 
A) All antihypertensive drugs can cause orthostatic hypotension. 
B) Thiazide diuretics have been shown to increase the risk of diabetes. 
C) A minimum target increase in heart rate during exercise should be 50 beats/min in patients receiving a beta-blocker. 
D) Environmental temperature can affect ADRs of antihypertensive drugs.

Question 19

The ethnic group most affected by hypertension is ___________.

Accepted Answer

A) white Americans 
B) black Americans 
C) Hispanics 
D) there is no difference among ethnic groups 
A) white Americans 
B) black Americans 
C) Hispanics 
D) there is no difference among ethnic groups

Question 20

Which of the following statements is false?

Accepted Answer

A) Normal blood pressure is considered to be 130 over 90 
B) Prehypertension is usually treated with diet and exercise 
C) Stage I hypertension may be treated first with thiazide diuretics followed by other antihypertensive drugs if needed 
D) Severe hypertension is usually treated with two or even three drug combinations 
A) Normal blood pressure is considered to be 130 over 90 
B) Prehypertension is usually treated with diet and exercise 
C) Stage I hypertension may be treated first with thiazide diuretics followed by other antihypertensive drugs if needed 
D) Severe hypertension is usually treated with two or even three drug combinations

Exam 6: Antihypertensive

Which of the following statements is false?

To maintain normal blood pressure,the body has reflex mechanisms available.Which of the following reflex mechanisms helps to maintain normal blood pressure?

An asymptomatic female athlete with mild hypertension (150/95 mm Hg)should be treated with which of the following regimens or drugs?

ACE inhibitors ___________.

Nonselective β-blockers can be used to treat hypertension and which of the following?

Angiotensin II ___________.

Which of the following is not a vasodilator?

Mean arterial pressure depends on ___________.

Why would a thiazide diuretic and a K⁺-sparing diuretic be administered together?

You are working with a patient who is on β-blockers.The resting heart rate is 80 bpm,and the resting BP is 135/90 mm Hg.Which of the following is an acceptable response to exercise?

The mechanism of action of calcium channel blockers is to ________________.

Vasoconstriction would be desired when it is necessary to ___________.

Therapeutic concerns with the use of diuretics include ___________.

Therapeutic actions of β-blockers include __________.

You are treating a patient with hypertension who is taking a β-blocker.Information regarding safe dosing and exercise include which of the following?

Which of the following statements is false?

The ethnic group most affected by hypertension is ___________.

Which of the following statements is false?

Introduction

Pharmacodynamics: Mechanism of Action

Pharmacokinetics and Drug Dosing

Adverse Drug Reactions

Drugs Acting on the Autonomic Nervous System

Drug Therapy of Coronary Atherosclerosis and Its Repercussions

Drug Therapy for Congestive Heart Failure and Cardiac Arrhythmias

Drug Therapy for Pulmonary Disorders

Anesthetic Agents

Drugs for the Treatment of Pain and Inflammation

Drug Treatment for Arthritis-Related Conditions

Selective Topics in Endocrine Pharmacology

Drug Treatment for Osteoporosis and Diabetes

Drugs for Epilepsy and Attention Deficit/Hyperactivity Disorder

Antispasticity Medications and Skeletal Muscle Relaxants

Pharmacologic Management of Degenerative Neurologic Disorders

Drug Treatment for Depression and Anxiety

Drug Treatment for Schizophrenia and Bipolar Illness

Antimicrobial Agents

Antiviral Agents and Selected Drugs for Fungal Infections

Cytotoxic Agents and Immune Modulation

Drugs for Gastrointestinal Disorders

Vitamins and Minerals

Topical Drugs and Treatments Used in Wound Management

Complementary and Alternative Medicine in Pharmacology

Drugs of Abuse: Anabolic Steroids and Other Doping Agents

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