Exam 38: Hemorrhagic Disorders and Laboratory Assessment

A 67-year-old woman arrives at the emergency department with acute bleeding into the back of the throat.A coagulation screen is ordered with the following results: Prothrombin time (PT) 12 seconds 11-15 seconds Partial thromboplastin time 57 seconds 25-37 seconds 36 (PTT) (immediate) Fibrinogen 450/ 150-400/ What would be a reasonable next step to perform?

Which of the following proteins is the best test to distinguish moderate to severe liver disease from vitamin K deficiency?

What coagulation screening test is the most sensitive for detecting mild liver disease?

Which patient group is most susceptible to bleeding because of a deficiency of vitamin K-dependent proteins?

What procedure is used to quantitate a factor VIII inhibitor?

What is or are the possible mechanism (or mechanisms)for bleeding in patients with severe liver disease?

Which type of VWD gives a positive response to low-dose ristocetin-induced platelet aggregation?

What is the purest form of factor VIII that is available for treating a bleeding patient with hemophilia A?

Two children in the same family have recurrent,chronic bruising in multiple sites,repeated long-lasting epistaxis,and minor bleeding after dental work.Which type of disorder is most likely?

Which of the following tests is increased in a patient with severe hemophilia A?

What test is useful for detection of a female carrier of hemophilia A?

What is the typical clinical picture in patients with severe hemophilia A?

What is the best test to distinguish hemophilia A from B or C?

Desmopressin acetate (DDAVP)is used to treat

What are the primary roles of VWF?

Which is the most common form of von Willebrand disease (VWD)?

Which of the following single-factor inherited deficiencies is most common as the cause for hemophilia?

The bleeding associated with renal disease is related most to defective

In what is a patient with the following coagulation test results most likely deficient? Prothrombin time (PT) 17 seconds 11-15 seconds Partial thromboplastin time (PTT) 31 seconds 25-37 seconds Thrombin time (TT) 16 seconds 15-21 seconds

All of the following can mask a deficiency of VWF and thus of type 1 VWD except