Question 1

Why is the white count in a normal full-term newborn elevated shortly after birth?

Accepted Answer

A) A relative loss of plasma occurs. 
B) An absolute increase in neutrophils occurs. 
C) An absolute increase in lymphocytes occurs. 
D) An absolute increase in both neutrophils and lymphocytes occurs. 
A) A relative loss of plasma occurs. 
B) An absolute increase in neutrophils occurs. 
C) An absolute increase in lymphocytes occurs. 
D) An absolute increase in both neutrophils and lymphocytes occurs. B

Question 2

All of the following are normal peripheral blood RBC findings at birth in a full-term infant except

Accepted Answer

A) nucleated RBCs 
B) Mean cell volume (MCV) less than 90 fL 
C) reticulocytosis of 5% 
D) hemoglobin of 20.2 g/dL 
A) nucleated RBCs 
B) Mean cell volume (MCV) less than 90 fL 
C) reticulocytosis of 5% 
D) hemoglobin of 20.2 g/dL B

Question 3

Which of the following is most commonly seen in the population older than70 years?

Accepted Answer

A) chronic lymphocytic leukemia 
B) chronic myelogenous leukemia 
C) essential thrombocytosis 
D) acute lymphocytic leukemia 
A) chronic lymphocytic leukemia 
B) chronic myelogenous leukemia 
C) essential thrombocytosis 
D) acute lymphocytic leukemia A

Question 4

What is the normal bone marrow cellularity in the population older than 65 years?

Accepted Answer

A) 90% 
B) 70% 
C) 50% 
D) 30% 
A) 90% 
B) 70% 
C) 50% 
D) 30%

Question 5

At what age is it normal for bone marrow cellularity to be 80% to 90% (i.e.,has very little fat)?

Accepted Answer

A) at birth 
B) in an 8-year-old 
C) in a 20 to 40-year-old 
D) in those older than 70 years 
A) at birth 
B) in an 8-year-old 
C) in a 20 to 40-year-old 
D) in those older than 70 years

Question 6

A Complete blood count (CBC)is requested on a full-term newborn girl,and the following results are obtained:
$ \begin{array}{ll}\mathrm{RBCs} & 5.07 \times 10^{12} / \mathrm{L} \ \text { Hemoglobin } & 14.4 \ \text { Hematocrit } & 44.5 \% \ \text { MCV } & 88 \mathrm{fL} \ \text { White blood cells (WBCs) } & 26.8 \times 10^{9 / \mathrm{L}} \ \text { Platelets } & 295 \times 10^{9} / \mathrm{L}\end{array} $
What conclusion can be made regarding these data for this infant?

Accepted Answer

A) All results are normal. 
B) The white count is elevated. 
C) Hemoglobin, hematocrit, and MCV are all decreased. 
D) Red cell count, hemoglobin, and hematocrit are all normal, but MCV is decreased. 
A) All results are normal. 
B) The white count is elevated. 
C) Hemoglobin, hematocrit, and MCV are all decreased. 
D) Red cell count, hemoglobin, and hematocrit are all normal, but MCV is decreased.

Question 7

What is the most likely reason that the red blood cell (RBC)count remains elevated in a newborn for the first 2 weeks of life?

Accepted Answer

A) A relative loss of plasma occurs during the birth process. 
B) A significantly longer RBC life span increases the number of red cells in circulation. 
C) Partial anoxia exists in utero, and erythropoietin increases. 
D) The switch from fetal to adult hemoglobin causes the number of red cells to increase. 
A) A relative loss of plasma occurs during the birth process. 
B) A significantly longer RBC life span increases the number of red cells in circulation. 
C) Partial anoxia exists in utero, and erythropoietin increases. 
D) The switch from fetal to adult hemoglobin causes the number of red cells to increase.

Question 8

Which of the following is more likely to result from poor absorption than from inadequate nutritional intake in older adults?

Accepted Answer

A) folic acid deficiency 
B) iron deficiency 
C) vitamin B12 deficiency 
D) lead deficiency 
A) folic acid deficiency 
B) iron deficiency 
C) vitamin B12 deficiency 
D) lead deficiency

Question 9

Which of the following is true concerning age-related changes of hemostasis in older adults?

Accepted Answer

A) decreased factor VIII 
B) decreased platelet activity 
C) increased fibrinogen 
D) increased fibrinolysis 
A) decreased factor VIII 
B) decreased platelet activity 
C) increased fibrinogen 
D) increased fibrinolysis

Question 10

Why is there a relative lymphocytosis in a 2-year-old?

Accepted Answer

A) An absolute neutropenia occurs. 
B) The absolute number of lymphocytes is increased as the immune system develops. 
C) A greater proportion of neutrophils are marginated. 
D) Fewer lymphocytes are marginated. 
A) An absolute neutropenia occurs. 
B) The absolute number of lymphocytes is increased as the immune system develops. 
C) A greater proportion of neutrophils are marginated. 
D) Fewer lymphocytes are marginated.

Question 11

A normal 3-month-old boy has a hemoglobin of 11.2 g/dL.Which of the following is true about his hemoglobin? It is

Accepted Answer

A) higher than that of a normal full-term newborn. 
B) lower than that of an adult of the same age. 
C) higher than that of a 14 year old of the same sex. 
D) the same as that of an adult of the same sex. 
A) higher than that of a normal full-term newborn. 
B) lower than that of an adult of the same age. 
C) higher than that of a 14 year old of the same sex. 
D) the same as that of an adult of the same sex.

Question 12

Iron deficiency anemia in older adults is most often a result of

Accepted Answer

A) poor nutritional intake of iron. 
B) malabsorption of iron. 
C) decreased ability to transport iron because of a decrease in transferrin. 
D) bleeding in the gastrointestinal tract. 
A) poor nutritional intake of iron. 
B) malabsorption of iron. 
C) decreased ability to transport iron because of a decrease in transferrin. 
D) bleeding in the gastrointestinal tract.

Question 13

Which of the following age groups normally has the lowest mean red cell values (red cell count,hemoglobin,hematocrit)?

Accepted Answer

A) preterm premature 
B) full-term newborn 
C) normal 2-year-old child 
D) normal 30-year-old woman 
A) preterm premature 
B) full-term newborn 
C) normal 2-year-old child 
D) normal 30-year-old woman

Question 14

An 85-year-old woman has a hemoglobin of 10.5 g/dL.This is

Accepted Answer

A) high for a woman of this age. 
B) normal for this age regardless of sex (i.e., for both male and female patients). 
C) a sign of an underlying disease and requires further evaluation. 
D) most likely a myelophthisic anemia. 
A) high for a woman of this age. 
B) normal for this age regardless of sex (i.e., for both male and female patients). 
C) a sign of an underlying disease and requires further evaluation. 
D) most likely a myelophthisic anemia.

Exam 45: Pediatric and Geriatric Hematology and Hemostasis

Why is the white count in a normal full-term newborn elevated shortly after birth?

All of the following are normal peripheral blood RBC findings at birth in a full-term infant except

Which of the following is most commonly seen in the population older than70 years?

What is the normal bone marrow cellularity in the population older than 65 years?

At what age is it normal for bone marrow cellularity to be 80% to 90% (i.e.,has very little fat)?

A Complete blood count (CBC)is requested on a full-term newborn girl,and the following results are obtained: 5.07\times1/ Hemoglobin 14.4 Hematocrit 44.5\% MCV 88 White blood cells (WBCs) 26.8\times1 Platelets 295\times1/ What conclusion can be made regarding these data for this infant?

What is the most likely reason that the red blood cell (RBC)count remains elevated in a newborn for the first 2 weeks of life?

Which of the following is more likely to result from poor absorption than from inadequate nutritional intake in older adults?

Which of the following is true concerning age-related changes of hemostasis in older adults?

Why is there a relative lymphocytosis in a 2-year-old?

A normal 3-month-old boy has a hemoglobin of 11.2 g/dL.Which of the following is true about his hemoglobin? It is

Iron deficiency anemia in older adults is most often a result of

Which of the following age groups normally has the lowest mean red cell values (red cell count,hemoglobin,hematocrit)?

An 85-year-old woman has a hemoglobin of 10.5 g/dL.This is

An Overview of Clinical Laboratory Hematology

Safety in the Hematology Laboratory

Blood Specimen Collection

Care and Use of the Microscope

Quality Assurance in Hematology and Hemostasis Testing

Cellular Structure and Function

Hematopoiesis

Erythrocyte Production and Destruction

Erythrocyte Metabolism and Membrane Structure and Function

Hemoglobin Metabolism

Iron Kinetics and Laboratory Assessment

Leukocyte Development, Kinetics, and Functions

Platelet Production, Structure, and Function

Manual, Semiautomated and Point-of-Care Testing in Hematology

Automated Blood Cell Analysis

Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count

Bone Marrow Examination

Body Fluid Analysis in the Hematology Laboratory

Anemias: Red Blood Cell Morphology and Approach to Diagnosis

Disorders of Iron Kinetics and Heme Metabolism

Anemias Caused by Defects of DNA Metabolism

Bone Marrow Failure

Introduction to Increased Destruction of Erythrocytes

Intrinsic Defects Leading to Increased Erythrocyte Destruction

Extrinsic Defects Leading to Increased Erythrocyte Destruction Nonimmune Causes

Extrinsic Defects Leading to Increased Erythrocyte Destruction Immune Causes

Hemoglobinopathies (Structural Defects in Hemoglobin)

Thalassemias

Nonmalignant Leukocyte Disorders

Cytogenetics

Molecular Diagnostics in Hematopathology

Flow Cytometric Analysis in Hematologic Disorders

Myeloproliferative Neoplasms

Myelodysplastic Syndromes

Acute Leukemias

Mature Lymphoid Neoplasms

Normal Hemostasis and Coagulation

Hemorrhagic Disorders and Laboratory Assessment

Thrombotic Disorders and Laboratory Assessment

Thrombocytopenia and Thrombocytosis

Qualitative Disorders of Platelets and Vasculature

Laboratory Evaluation of Hemostasis

Antithrombotic Therapies and their Laboratory Assessment

Hemostasis and Coagulation Instrumentation

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