Exam 36: Mature Lymphoid Neoplasms

Serum protein electrophoresis on an elderly patient reveals a monoclonal protein spike.Increased plasma cells are present in the bone marrow.They are CD19 and CD20 negative but demonstrate high-density CD38 and monoclonal cytoplasmic immunoglobulin.What is the most likely diagnosis?

Malignant proliferation of plasma cells with osteolytic bone lesions and the presence of monoclonal immunoglobulin in the serum describes

Which of the following are mature pan-T cell markers?

Where are malignant plasma cells found in plasma cell myeloma?

Which of the following are mature pan-B cell markers?

Mature T cells with cerebriform,clefted nuclei found in the skin and peripheral blood describe

The strongest risk factor for development of a lymphoproliferative disorders is

Why are patients with plasma cell myeloma susceptible to infection?

What is the clinical significance of an enlarged lymph node?

What is the diagnostic cell,found in involved lymph nodes,for Hodgkin lymphoma?

What is the preferred specimen to evaluate cellular morphology in the lymphoproliferative disorders?

Which of the following is true regarding the clinical course of chronic lymphocytic leukemia?

Which of the following is true of plasma cells?

Neoplastic lymphocytes with noncleaved clumped nuclei and very basophilic cytoplasm with prominent vacuoles describes

Normal lymph nodes contain all of the following cell types except

What lymphoproliferative disorder has a very favorable response to highly aggressive chemotherapy with no radiotherapy?

All of the following are functions of normal lymph nodes except

Which of the following is true regarding classic Hodgkin lymphoma?

Why is Burkitt lymphoma such an aggressive malignancy?

A middle-aged man has a white blood cell (WBC)count of 80 × 10⁹/L with 90% lymphocytes and many smudge cells.Which of the following is most likely?