Exam 35: Acute Leukemias

A 27-year-old woman arrives at the emergency department with acute bleeding and is found to have a white count of 25.7 × 10⁹L with pancytopenia: hematocrit 27%,platelet count 35 × 10⁹/L,and absolute neutrophil count 0.8 × 10⁹/L.She has a combination of 97% blasts and abnormal promyelocytes in her peripheral blood;some of these cells contain Auer rods.What form of leukemia does she most likely have?

Which of the following would stain most strongly for myeloperoxidase?

Which form of acute myeloid leukemia is most often associated with disseminated intravascular coagulation (DIC)?

What leukemia is most likely in a patient whose bone marrow is composed of predominantly large,multinucleated,vacuolated,dysplastic erythroid precursors?

Which form of acute leukemia has megakaryoblasts and antibodies to platelet glycoprotein IIb/IIIa?

A patient has a very high white blood cell count with many blasts in the blood and bone marrow.Esterase stains using both naphthol AS-D chloroacetate and a-naphthyl acetate esterase as substrates are both positive.What condition is likely?

Acute myelomonocytic leukemia is positive for which of the following?

An adult patient has a white blood count of 80 × 10⁹/L.The differential has 92% Sudan black B-positive blasts and 8% lymphocytes.Which of the following is most likely?

A 15-year-old boy is complaining of severe headaches;he has a white count of 76.0 × 10⁹/L,platelet count of 55 × 10⁹/L,and a hematocrit of 33%.When a white cell differential is performed,most of the nucleated cells are blasts.They are CD2,CD4,and CD8 positive.The TdT marker is expressed.What is the most likely diagnosis?

A 47-year-old man has gingival hypertrophy and a white blood cell (WBC)count of 108 × 10⁹/L.He has a moderate anemia and is thrombocytopenic.The differential consists primarily of a combination of mature monocytes,promonocytes,and CD14-positive blasts.Which of the following forms of leukemia is most likely?

Sudan Black is used to distinguish which types of leukemia?

What is the most common leukemia in children between the ages of 2 and 5 years?