Question 1

How does the genetically active portion of the nuclear chromatin look when stained with Wright stain?

Accepted Answer

A) condensed, darkly stained 
B) clumped, dark purple 
C) ropelike, pink or red 
D) diffuse, uncondensed and pale blue 
A) condensed, darkly stained 
B) clumped, dark purple 
C) ropelike, pink or red 
D) diffuse, uncondensed and pale blue D

Question 2

What cellular component "directs traffic" for smooth functioning?

Accepted Answer

A) mitochondria 
B) ribosomes 
C) Golgi complex 
D) nucleoli 
A) mitochondria 
B) ribosomes 
C) Golgi complex 
D) nucleoli C

Question 3

After birth,where does hematopoiesis predominantly occur?

Accepted Answer

A) bone marrow 
B) spleen 
C) liver 
D) lymph nodes 
A) bone marrow 
B) spleen 
C) liver 
D) lymph nodes A

Question 4

In what stage of the cell cycle does DNA replication occur?

Accepted Answer

A) G1 
B) S 
C) G2 
D) M 
A) G1 
B) S 
C) G2 
D) M

Question 5

What cellular structures appear as granules with Wright stain?

Accepted Answer

A) ribosomes 
B) Golgi bodies 
C) mitochondria 
D) lysosomes 
A) ribosomes 
B) Golgi bodies 
C) mitochondria 
D) lysosomes

Question 6

Which of the following morphologic characteristics is representative of apoptosis?

Accepted Answer

A) inflammation 
B) cell swelling 
C) cell shrinkage 
D) cell lysis 
A) inflammation 
B) cell swelling 
C) cell shrinkage 
D) cell lysis

Question 7

Protein synthesis occurs in what part of a cell?

Accepted Answer

A) ribosomes 
B) nucleus 
C) mitochondria 
D) lysosomes 
A) ribosomes 
B) nucleus 
C) mitochondria 
D) lysosomes

Question 8

The nucleolus of a cell is composed of

Accepted Answer

A) hydrolytic enzymes. 
B) glycoproteins. 
C) RNA. 
D) lipids. 
A) hydrolytic enzymes. 
B) glycoproteins. 
C) RNA. 
D) lipids.

Question 9

Erythropoietin is a growth factor affecting erythroid progenitors and is produced by what organ?

Accepted Answer

A) bone marrow 
B) spleen 
C) kidney 
D) liver 
A) bone marrow 
B) spleen 
C) kidney 
D) liver

Question 10

Lysosomes are found in the cytoplasm of many cells and contain

Accepted Answer

A) cholesterol. 
B) hydrolytic enzymes. 
C) glycoproteins. 
D) RNA. 
A) cholesterol. 
B) hydrolytic enzymes. 
C) glycoproteins. 
D) RNA.

Question 11

Where are surface markers that help in cell identification found?

Accepted Answer

A) cell membrane 
B) Golgi complex 
C) rough endoplasmic reticulum 
D) nucleus 
A) cell membrane 
B) Golgi complex 
C) rough endoplasmic reticulum 
D) nucleus

Question 12

If the lysosomal membrane ruptures,what is the consequence to the cell?

Accepted Answer

A) activates cell nucleus to replicate DNA 
B) enhances protein synthesis by ribosomes 
C) damages internal cell structures 
D) facilitates rearrangement of intracellular organelles 
A) activates cell nucleus to replicate DNA 
B) enhances protein synthesis by ribosomes 
C) damages internal cell structures 
D) facilitates rearrangement of intracellular organelles

Question 13

What cellular component is responsible for energy production and metabolic processes?

Accepted Answer

A) ribosomes 
B) nucleus 
C) mitochondria 
D) lysosomes 
A) ribosomes 
B) nucleus 
C) mitochondria 
D) lysosomes

Question 14

If the cytoplasm of a cell is very basophilic or blue when stained with Wright stain it contains

Accepted Answer

A) low concentration of lysosomes. 
B) large number of ribosomes. 
C) small number of ribosomes. 
D) high concentration of lysosomes. 
A) low concentration of lysosomes. 
B) large number of ribosomes. 
C) small number of ribosomes. 
D) high concentration of lysosomes.

Question 15

What component of the erythrocyte is most responsible for its cytoskeleton and cellular integrity?

Accepted Answer

A) glycocalyx 
B) cytoskeletal protein 
C) nucleus 
D) Golgi complex 
A) glycocalyx 
B) cytoskeletal protein 
C) nucleus 
D) Golgi complex

Question 16

What cellular component of the erythrocyte is its control center?

Accepted Answer

A) heterochromatin 
B) Golgi complex 
C) nucleus 
D) cytoplasm 
A) heterochromatin 
B) Golgi complex 
C) nucleus 
D) cytoplasm

Question 17

A cell that is actively synthesizing protein has

Accepted Answer

A) more nucleoli. 
B) more heterochromatin. 
C) fewer ribosomes. 
D) fewer mitochondria. 
A) more nucleoli. 
B) more heterochromatin. 
C) fewer ribosomes. 
D) fewer mitochondria.

Exam 6: Cellular Structure and Function

How does the genetically active portion of the nuclear chromatin look when stained with Wright stain?

What cellular component "directs traffic" for smooth functioning?

After birth,where does hematopoiesis predominantly occur?

In what stage of the cell cycle does DNA replication occur?

What cellular structures appear as granules with Wright stain?

Which of the following morphologic characteristics is representative of apoptosis?

Protein synthesis occurs in what part of a cell?

The nucleolus of a cell is composed of

Erythropoietin is a growth factor affecting erythroid progenitors and is produced by what organ?

Lysosomes are found in the cytoplasm of many cells and contain

Where are surface markers that help in cell identification found?

If the lysosomal membrane ruptures,what is the consequence to the cell?

What cellular component is responsible for energy production and metabolic processes?

If the cytoplasm of a cell is very basophilic or blue when stained with Wright stain it contains

What component of the erythrocyte is most responsible for its cytoskeleton and cellular integrity?

What cellular component of the erythrocyte is its control center?

A cell that is actively synthesizing protein has

An Overview of Clinical Laboratory Hematology

Safety in the Hematology Laboratory

Blood Specimen Collection

Care and Use of the Microscope

Quality Assurance in Hematology and Hemostasis Testing

Hematopoiesis

Erythrocyte Production and Destruction

Erythrocyte Metabolism and Membrane Structure and Function

Hemoglobin Metabolism

Iron Kinetics and Laboratory Assessment

Leukocyte Development, Kinetics, and Functions

Platelet Production, Structure, and Function

Manual, Semiautomated and Point-of-Care Testing in Hematology

Automated Blood Cell Analysis

Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count

Bone Marrow Examination

Body Fluid Analysis in the Hematology Laboratory

Anemias: Red Blood Cell Morphology and Approach to Diagnosis

Disorders of Iron Kinetics and Heme Metabolism

Anemias Caused by Defects of DNA Metabolism

Bone Marrow Failure

Introduction to Increased Destruction of Erythrocytes

Intrinsic Defects Leading to Increased Erythrocyte Destruction

Extrinsic Defects Leading to Increased Erythrocyte Destruction Nonimmune Causes

Extrinsic Defects Leading to Increased Erythrocyte Destruction Immune Causes

Hemoglobinopathies (Structural Defects in Hemoglobin)

Thalassemias

Nonmalignant Leukocyte Disorders

Cytogenetics

Molecular Diagnostics in Hematopathology

Flow Cytometric Analysis in Hematologic Disorders

Myeloproliferative Neoplasms

Myelodysplastic Syndromes

Acute Leukemias

Mature Lymphoid Neoplasms

Normal Hemostasis and Coagulation

Hemorrhagic Disorders and Laboratory Assessment

Thrombotic Disorders and Laboratory Assessment

Thrombocytopenia and Thrombocytosis

Qualitative Disorders of Platelets and Vasculature

Laboratory Evaluation of Hemostasis

Antithrombotic Therapies and their Laboratory Assessment

Hemostasis and Coagulation Instrumentation

Pediatric and Geriatric Hematology and Hemostasis

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