Question 1

Which of the following stimulate macrophage differentiation and activation?

Accepted Answer

A)  tumor necrosis factor- alpha 
B)  interferon gamma 
C)  granulocyte- monocyte colony stimulating factor 
D)  all of the above 
A)  tumor necrosis factor- alpha 
B)  interferon gamma 
C)  granulocyte- monocyte colony stimulating factor 
D)  all of the above

Question 2

The mechanism by which antigen- reactive cells respond to foreign antigens while ignoring self- antigens is called________ .

Accepted Answer

The answer of The mechanism by which antigen- reactive cells...

Question 3

What role does the C domain play in cell surface proteins that interact directly with antigens?

Accepted Answer

C domains provide structural integrity f

Question 4

The arrangement of Class II MHC proteins in pairs or trimers enhances their stability.

Accepted Answer

A) True 
 B)False

Question 5

The cytoplasmic domains of immunoglobulins and TCRs have cytoplasmic tyrosines that can be phosphorylated.

Accepted Answer

A) True 
 B)False

Question 6

Each immunoglobulin or TCR interacts with a single antigen, but MHC proteins can interact with more than one antigen.

Accepted Answer

A) True 
 B)False

Question 7

Somatic hypermutation occurs only in the________ regions of rearranged heavy and light chains.

Accepted Answer

A)  HV 
B)  J 
C)  D 
D)  V 
A)  HV 
B)  J 
C)  D 
D)  V

Question 8

Immunoglobins associate with the adapter molecules Iga and Igfi.

Accepted Answer

A) True 
 B)False

Question 9

Which of the following are soluble mediators and activators for T lymphocytes and B cells?

Accepted Answer

A)  IL- 5 
B)  IL- 2 
C)  IL- 4 
D)  all of the above 
A)  IL- 5 
B)  IL- 2 
C)  IL- 4 
D)  all of the above

Question 10

C- reactive protein is a(n)

Accepted Answer

A)  acute phase protein. 
B)  type of PAMP. 
C)  lipoprotein. 
D)  homotrimeric adaptor protein. 
A)  acute phase protein. 
B)  type of PAMP. 
C)  lipoprotein. 
D)  homotrimeric adaptor protein.

Question 11

In somatic hypermutation, the mutation of immunoglobulin genes occurs at much higher rates than the mutation rates observed in other genes.

Accepted Answer

A) True 
 B)False

Question 12

What is the effect of an antigen binding a membrane protein on adapter molecules?

Accepted Answer

Antigen binding by immunoglobulin or TCR

Question 13

Chemokines are a group of small proteins that

Accepted Answer

A)  potentiate specific immune responses. 
B)  function as chemoattractants for phagocytes and lymphocytes. 
C)  attract T cells to sites of injury. 
D)  are all of the above. 
A)  potentiate specific immune responses. 
B)  function as chemoattractants for phagocytes and lymphocytes. 
C)  attract T cells to sites of injury. 
D)  are all of the above.

Question 14

In B cell selection and tolerance, if no signal is generated from________ cells, the B cells remains unresponsive.

Accepted Answer

The answer of In B cell selection and tolerance, if...

Question 15

TCRs are found exclusively on T cells.

Accepted Answer

A) True 
 B)False

Question 16

The C domain of antigen- binding proteins has approximately ________amino acids.

Accepted Answer

A)  400 
B)  300 
C)  100 
D)  200 
A)  400 
B)  300 
C)  100 
D)  200

Question 17

Interaction of a PAMP with a TLR triggers transmembrane________ .

Accepted Answer

signal tra

Question 18

Affinity maturation is one of the factors responsible for a stronger secondary immune response.

Accepted Answer

A) True 
 B)False

Question 19

More than _________ % of all T cell precursors that enter the thymus do not survive the selection process.

Accepted Answer

A)  15 
B)  25 
C)  95 
D)  45 
A)  15 
B)  25 
C)  95 
D)  45

Question 20

Which of the following contribute to the limitless diversity generated from a relatively fixed number of immunoglobulin genes?

Accepted Answer

A)  random heavy and light chain reassortment 
B)  hypermutation 
C)  somatic recombination 
D)  all of the above 
A)  random heavy and light chain reassortment 
B)  hypermutation 
C)  somatic recombination 
D)  all of the above

Exam 30: Molecular Immunology

Which of the following stimulate macrophage differentiation and activation?

The mechanism by which antigen- reactive cells respond to foreign antigens while ignoring self- antigens is called________ .

What role does the C domain play in cell surface proteins that interact directly with antigens?

The arrangement of Class II MHC proteins in pairs or trimers enhances their stability.

The cytoplasmic domains of immunoglobulins and TCRs have cytoplasmic tyrosines that can be phosphorylated.

Each immunoglobulin or TCR interacts with a single antigen, but MHC proteins can interact with more than one antigen.

Somatic hypermutation occurs only in the________ regions of rearranged heavy and light chains.

Immunoglobins associate with the adapter molecules Iga and Igfi.

Which of the following are soluble mediators and activators for T lymphocytes and B cells?

C- reactive protein is a(n)

In somatic hypermutation, the mutation of immunoglobulin genes occurs at much higher rates than the mutation rates observed in other genes.

What is the effect of an antigen binding a membrane protein on adapter molecules?

Chemokines are a group of small proteins that

In B cell selection and tolerance, if no signal is generated from________ cells, the B cells remains unresponsive.

TCRs are found exclusively on T cells.

The C domain of antigen- binding proteins has approximately ________amino acids.

Interaction of a PAMP with a TLR triggers transmembrane________ .

Affinity maturation is one of the factors responsible for a stronger secondary immune response.

More than _________ % of all T cell precursors that enter the thymus do not survive the selection process.

Which of the following contribute to the limitless diversity generated from a relatively fixed number of immunoglobulin genes?

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