Question 1

Antibodies are insoluble proteins.

Accepted Answer

A) True 
 B)False  False

Question 2

Class II MHC proteins have groves with

Accepted Answer

A)  both open and closed ends. 
B)  open ends. 
C)  closed ends. 
D)  none of the above. 
A)  both open and closed ends. 
B)  open ends. 
C)  closed ends. 
D)  none of the above. B

Question 3

The PAMP recognized by mannose- binding lectin (MBL) is the sugar________ , found as a repeating subunit in bacterial and fungal polysaccharides.

Accepted Answer

mannose

Question 4

Which of the following proteins interact with TLR- 4?

Accepted Answer

A)  heat shock proteins 
B)  bacterial LPS 
C)  both LPS and heat shock proteins 
D)  none of the above 
A)  heat shock proteins 
B)  bacterial LPS 
C)  both LPS and heat shock proteins 
D)  none of the above

Question 5

Intercellular communication in the immune system is accomplished in many cases through

Accepted Answer

A)  cytokines. 
B)  clonal deletion. 
C)  allelic exclusion. 
D)  all of the above. 
A)  cytokines. 
B)  clonal deletion. 
C)  allelic exclusion. 
D)  all of the above.

Question 6

Amino acid variability is especially apparent in several________in the V domains of different immunoglobulins.

Accepted Answer

complement

Question 7

Immunoglobulin, TCR, and MHC proteins share structural features and have evolved by duplication and selection of primordial antigen receptors.

Accepted Answer

A) True 
 B)False

Question 8

The chemokine CCL2

Accepted Answer

A)  stimulates production of inflammatory mediators. 
B)  attracts basophils, eosinophils, monocytes, and dendritic cells. 
C)  organizes an antigen specific immune response. 
D)  is all of the above. 
A)  stimulates production of inflammatory mediators. 
B)  attracts basophils, eosinophils, monocytes, and dendritic cells. 
C)  organizes an antigen specific immune response. 
D)  is all of the above.

Question 9

The two- stage thymic selection process for selecting self- tolerant, antigen- reactive T cells results in

Accepted Answer

A)  somatic hypermutation. 
B)  allelic exclusion. 
C)  clonal deletion. 
D)  complementarity- determining regions. 
A)  somatic hypermutation. 
B)  allelic exclusion. 
C)  clonal deletion. 
D)  complementarity- determining regions.

Question 10

Signal transduction pathways initiate activation of transcription through ________binding on the cell surface.

Accepted Answer

The answer of Signal transduction pathways initiate activation of transcription...

Question 11

After a B cell is activated, it no longer needs T cell interactions or cytokines to make antibody.

Accepted Answer

A) True 
 B)False

Question 12

Which of the following is involved in B cell selection and tolerance?

Accepted Answer

A)  clonal anergy and deletion 
B)  clonal deletion 
C)  clonal anergy 
D)  none of the above 
A)  clonal anergy and deletion 
B)  clonal deletion 
C)  clonal anergy 
D)  none of the above

Question 13

The target for TLR- 5 is________ .

Accepted Answer

The answer of The target for TLR- 5 is________ ....

Question 14

Each of the V domains in immunoglobulins has ________ complementarity- determining regions.

Accepted Answer

A)  one 
B)  two 
C)  three 
D)  four 
A)  one 
B)  two 
C)  three 
D)  four

Question 15

The embedded peptides in MHC proteins are normally derived from breakdown products of cell metabolism.

Accepted Answer

A) True 
 B)False

Question 16

Briefly describe the structure of Class I MHC proteins.

Accepted Answer

Class I MHC proteins consist of two poly

Question 17

The failure to develop tolerance may result in dangerous reactions to self- antigens, a condition called________ .

Accepted Answer

The answer of The failure to develop tolerance may result...

Question 18

________ensures that each B cell produces only one immunoglobulin.

Accepted Answer

The answer of ________ensures that each B cell produces only...

Question 19

Chemokines produced by activated macrophages include

Accepted Answer

A)  CXL8. 
B)  MCP- 1. 
C)  CCL2. 
D)  all of the above. 
A)  CXL8. 
B)  MCP- 1. 
C)  CCL2. 
D)  all of the above.

Question 20

The ________is a highly conserved amino acid sequence found in immunoglobulin, TCR, and MHC proteins.

Accepted Answer

The answer of The ________is a highly conserved amino acid...

Exam 30: Molecular Immunology

Antibodies are insoluble proteins.

Class II MHC proteins have groves with

The PAMP recognized by mannose- binding lectin (MBL) is the sugar________ , found as a repeating subunit in bacterial and fungal polysaccharides.

Which of the following proteins interact with TLR- 4?

Intercellular communication in the immune system is accomplished in many cases through

Amino acid variability is especially apparent in several________in the V domains of different immunoglobulins.

Immunoglobulin, TCR, and MHC proteins share structural features and have evolved by duplication and selection of primordial antigen receptors.

The chemokine CCL2

The two- stage thymic selection process for selecting self- tolerant, antigen- reactive T cells results in

Signal transduction pathways initiate activation of transcription through ________binding on the cell surface.

After a B cell is activated, it no longer needs T cell interactions or cytokines to make antibody.

Which of the following is involved in B cell selection and tolerance?

The target for TLR- 5 is________ .

Each of the V domains in immunoglobulins has ________ complementarity- determining regions.

The embedded peptides in MHC proteins are normally derived from breakdown products of cell metabolism.

Briefly describe the structure of Class I MHC proteins.

The failure to develop tolerance may result in dangerous reactions to self- antigens, a condition called________ .

________ensures that each B cell produces only one immunoglobulin.

Chemokines produced by activated macrophages include

The ________is a highly conserved amino acid sequence found in immunoglobulin, TCR, and MHC proteins.

Microorganisms and Microbiology

A Brief Journey to the Microbial World

Cell Structure and Function in Bacteria and Archaea

Nutrition, Culture, and Metabolism of Microorganisms

Microbial Growth

Molecular Biology of Bacteria

Archael and Eukaryotic Molecular Biology

Regulation of Gene Expression

Viruses and Virology

Genetics of Bacteria and Arachaea

Genetic Engineering

Microbial Genomics

Phototrophy, Chemolithotrophy, and Major Biosyntheses

Catabolism of Organic Compounds

Commercial Products and Biotechnology

Microbial Evolution and Systematics

Bacteria: the Proteobacteria

Other Bacteria

Archaea

Eukaryotic Cell Biology and Eukaryotic Microorganisms

Viral Diversity

Methods in Microbial Ecology

Major Microbial Habitats and Diversity

Nutrient Cycles, Biodegradation, and Bioremediation

Microbial Symbioses

Microbial Growth Control

Microbial Interactions With Humans

Immunity and Host Defense

Immune Mechanisms

Diagnostic Microbiology and Immunology

Epidemiology

Person-To-Person Microbial Diseases

Vectorborne and Soilborne Microbial Pathogens

Wastewater Treatment, Water Purification, and Waterborne Microbial Diseases

Food Preservation and Foodborne Microbial Diseases

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