Question 1

Quinolones are contraindicated in pregnant women and children for what reason?

Accepted Answer

A)  They are ototoxic at small doses 
B)  They can permanently discolour teeth 
C)  They can damage developing joints permanently 
D)  They are only useful for Gram positive bacterium 
A)  They are ototoxic at small doses 
B)  They can permanently discolour teeth 
C)  They can damage developing joints permanently 
D)  They are only useful for Gram positive bacterium C

Question 2

Which antibacterial agent can cause permanent tooth discoloration in children?

Accepted Answer

A)  Tetracycline 
B)  Erythromycin 
C)  Penicillin 
D)  Cephalosporin 
A)  Tetracycline 
B)  Erythromycin 
C)  Penicillin 
D)  Cephalosporin A

Question 3

Colistin is available for delivery by which routes of administration?

Accepted Answer

A)  Intramuscular 
B)  Intravenous 
C)  Inhalation 
D)  All of the above 
A)  Intramuscular 
B)  Intravenous 
C)  Inhalation 
D)  All of the above D

Question 4

Cross-sensitivity can occur between penicillin and which other drugs?

Accepted Answer

A)  Cephalosporins 
B)  Carbapenems 
C)  β-lactams 
D)  All of the above 
A)  Cephalosporins 
B)  Carbapenems 
C)  β-lactams 
D)  All of the above

Question 5

What lab values should be monitored when daptomycin is prescribed?

Accepted Answer

A)  Potassium 
B)  Creatinine kinase 
C)  Phosphorous 
D)  Glucose 
A)  Potassium 
B)  Creatinine kinase 
C)  Phosphorous 
D)  Glucose

Question 6

Administration of the antibacterial agent ________ may cause prolongation of the QT interval and development of serious ventricular dysrhythmias.

Accepted Answer

A)  erythromycin or clarithromycin 
B)  benzylpenicillin or amoxycillin 
C)  tetracycline or doxycycline 
D)  gentamicin or tobramycin 
A)  erythromycin or clarithromycin 
B)  benzylpenicillin or amoxycillin 
C)  tetracycline or doxycycline 
D)  gentamicin or tobramycin

Question 7

What is the indication for rifaxim?

Accepted Answer

A)  Hepatic encephalopathy 
B)  Viral encephalitis 
C)  Hepatitis 
D)  Hepatic insufficiency 
A)  Hepatic encephalopathy 
B)  Viral encephalitis 
C)  Hepatitis 
D)  Hepatic insufficiency

Question 8

Which serious adverse effect is associated with long term use of nitrofurantoin?

Accepted Answer

A)  Iridescent yellow urine 
B)  Drowsiness 
C)  Paraethesia 
D)  Gastrointestinal upset 
A)  Iridescent yellow urine 
B)  Drowsiness 
C)  Paraethesia 
D)  Gastrointestinal upset

Question 9

Which drug group is considered a suitable alternative to penicillins when there is a known allergy?

Accepted Answer

A)  The macrolides 
B)  The cephalosporins 
C)  Gycopeptide antibacterials such as vancomycin 
D)  The quinolones 
A)  The macrolides 
B)  The cephalosporins 
C)  Gycopeptide antibacterials such as vancomycin 
D)  The quinolones

Question 10

The aminoglycosides are particularly toxic to what areas? Select all that apply.

Accepted Answer

A)  Kidneys 
B)  Liver 
C)  Eighth cranial nerve 
D)  Neuromuscular junction 
E)  Temporal mandibular joint 
A)  Kidneys 
B)  Liver 
C)  Eighth cranial nerve 
D)  Neuromuscular junction 
E)  Temporal mandibular joint

Question 11

When a person commences therapy with tetracycline,they should be advised to:

Accepted Answer

A)  cease therapy when they feel better. 
B)  avoid ingestion just before bedtime. 
C)  take it with meals. 
D)  regard abdominal pain as a tolerable side effect and not to bother their health professional about it. 
A)  cease therapy when they feel better. 
B)  avoid ingestion just before bedtime. 
C)  take it with meals. 
D)  regard abdominal pain as a tolerable side effect and not to bother their health professional about it.

Question 12

An example of a broad-spectrum penicillin is:

Accepted Answer

A)  amoxycillin. 
B)  clavulanic acid. 
C)  flucloxacillin. 
D)  procaine penicillin. 
A)  amoxycillin. 
B)  clavulanic acid. 
C)  flucloxacillin. 
D)  procaine penicillin.

Question 13

Which one of the following antibacterial drug groups acts by inhibiting microbial cell wall synthesis?

Accepted Answer

A)  Quinolones 
B)  Macrolides 
C)  Nitroimidazoles 
D)  Glycopeptide antibacterials 
A)  Quinolones 
B)  Macrolides 
C)  Nitroimidazoles 
D)  Glycopeptide antibacterials

Question 14

What medication regimen is ineffective in treating microorganisms that are part of the ESCAAPPM group?

Accepted Answer

A)  A carbapenem agent 
B)  A penicillin agent 
C)  An aminoglycoside agent 
D)  A fluoroquinolone agent 
A)  A carbapenem agent 
B)  A penicillin agent 
C)  An aminoglycoside agent 
D)  A fluoroquinolone agent

Question 15

Which one of the following is NOT a common adverse effect of treatment with penicillin?

Accepted Answer

A)  Photosensitivity 
B)  Nausea or vomiting 
C)  Oedema 
D)  The appearance of a rash or urticaria 
A)  Photosensitivity 
B)  Nausea or vomiting 
C)  Oedema 
D)  The appearance of a rash or urticaria

Question 16

How often should aminoglycoside antimicrobial agents be administered?

Accepted Answer

A)  Once daily 
B)  Two times a day 
C)  Three times a day 
D)  Four times a day 
A)  Once daily 
B)  Two times a day 
C)  Three times a day 
D)  Four times a day

Question 17

The main monobactam in use is:

Accepted Answer

A)  imipenem. 
B)  aztreonam. 
C)  ertapenem. 
D)  doripenem. 
A)  imipenem. 
B)  aztreonam. 
C)  ertapenem. 
D)  doripenem.

Exam 69: Antibacterial Agents

Quinolones are contraindicated in pregnant women and children for what reason?

Which antibacterial agent can cause permanent tooth discoloration in children?

Colistin is available for delivery by which routes of administration?

Cross-sensitivity can occur between penicillin and which other drugs?

What lab values should be monitored when daptomycin is prescribed?

Administration of the antibacterial agent ________ may cause prolongation of the QT interval and development of serious ventricular dysrhythmias.

What is the indication for rifaxim?

Which serious adverse effect is associated with long term use of nitrofurantoin?

Which drug group is considered a suitable alternative to penicillins when there is a known allergy?

The aminoglycosides are particularly toxic to what areas? Select all that apply.

When a person commences therapy with tetracycline,they should be advised to:

An example of a broad-spectrum penicillin is:

Which one of the following antibacterial drug groups acts by inhibiting microbial cell wall synthesis?

What medication regimen is ineffective in treating microorganisms that are part of the ESCAAPPM group?

Which one of the following is NOT a common adverse effect of treatment with penicillin?

How often should aminoglycoside antimicrobial agents be administered?

The main monobactam in use is:

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