Question 1

A drug mechanism that works to neutralise stomach acid is considered to be:

Accepted Answer

A)  an action targeting ion channels. 
B)  a chemical action. 
C)  an agonist action. 
D)  a physical action. 
A)  an action targeting ion channels. 
B)  a chemical action. 
C)  an agonist action. 
D)  a physical action. B

Question 2

Which one of the following statements about pharmacodynamics is true?

Accepted Answer

A)  A partial agonist can be as effective as an antagonist. 
B)  Ion channels do not have receptors. 
C)  Second messenger systems always involve G-proteins. 
D)  The antiasthma agent theophylline acts via a tyrosine kinase-linked receptor. 
A)  A partial agonist can be as effective as an antagonist. 
B)  Ion channels do not have receptors. 
C)  Second messenger systems always involve G-proteins. 
D)  The antiasthma agent theophylline acts via a tyrosine kinase-linked receptor. A

Question 3

Competitive inhibition slows down the rate of normal chemical reactions because:

Accepted Answer

A)  the normal substrate is malfunctioning. 
B)  the target enzyme binds temporarily with a look-alike substrate rather than its actual substrate. 
C)  it takes a long time for the enzyme to develop memory or recognition of the competing substances. 
D)  it causes enzyme confusion. 
A)  the normal substrate is malfunctioning. 
B)  the target enzyme binds temporarily with a look-alike substrate rather than its actual substrate. 
C)  it takes a long time for the enzyme to develop memory or recognition of the competing substances. 
D)  it causes enzyme confusion. B

Question 4

In general,a medicine that acts by chemical or physical means can be identified by its dose,which is considerably higher than that required by medicines that act by interacting with a receptor or enzyme system.

Accepted Answer

A) True 
 B)False

Question 5

In disrupting the synthesis of folic acid in bacteria,sulfonamides act:

Accepted Answer

A)  as competitive inhibitors. 
B)  as non-competitive inhibitors. 
C)  by physical action. 
D)  by none of the above. 
A)  as competitive inhibitors. 
B)  as non-competitive inhibitors. 
C)  by physical action. 
D)  by none of the above.

Question 6

The extent of binding of a drug to a receptor is termed:

Accepted Answer

A)  potency. 
B)  specificity. 
C)  affinity. 
D)  efficacy. 
A)  potency. 
B)  specificity. 
C)  affinity. 
D)  efficacy.

Question 7

When a drug acts through non-competitive inhibition of an enzyme,it:

Accepted Answer

A)  can be overcome by giving more of the enzyme substrate. 
B)  is usually reversible. 
C)  binds to a distinct site away from the active site. 
D)  is lethal to the person receiving treatment. 
A)  can be overcome by giving more of the enzyme substrate. 
B)  is usually reversible. 
C)  binds to a distinct site away from the active site. 
D)  is lethal to the person receiving treatment.

Question 8

Some terms that describe interactions between drugs and receptors include: (Select all that apply)

Accepted Answer

A)  antagonism. 
B)  agonism. 
C)  first mechanism 
D)  first messenger 
A)  antagonism. 
B)  agonism. 
C)  first mechanism 
D)  first messenger

Question 9

Pharmacodynamics describes the physiological processes that act on a drug once it enters the body,or how the body handles the drug.

Accepted Answer

A) True 
 B)False

Question 10

Pharmacological effect is achieved by:

Accepted Answer

A)  the portion of free or unbound drug. 
B)  the portion of protein-bound drug. 
C)  ionisation. 
D)  penetrating the blood-brain barrier. 
A)  the portion of free or unbound drug. 
B)  the portion of protein-bound drug. 
C)  ionisation. 
D)  penetrating the blood-brain barrier.

Exam 16: Pharmacodynamics

A drug mechanism that works to neutralise stomach acid is considered to be:

Which one of the following statements about pharmacodynamics is true?

Competitive inhibition slows down the rate of normal chemical reactions because:

In general,a medicine that acts by chemical or physical means can be identified by its dose,which is considerably higher than that required by medicines that act by interacting with a receptor or enzyme system.

In disrupting the synthesis of folic acid in bacteria,sulfonamides act:

The extent of binding of a drug to a receptor is termed:

When a drug acts through non-competitive inhibition of an enzyme,it:

Some terms that describe interactions between drugs and receptors include: (Select all that apply)

Pharmacodynamics describes the physiological processes that act on a drug once it enters the body,or how the body handles the drug.

Pharmacological effect is achieved by:

Sociocultural Aspects

Health Professionals and the Law

Ethical Issues

the Roles and Responsibilities of Health Professionals in Medicine Adherence, Education and Advocacy

the Roles and Responsibilities of Health Professionals in Medicine Management

Medicine Formulations, Storage and Routes of Administration

the Clinical Decision-making Process

Medicine Administration Strategies and Documentation

Medication Errors

Management of Common Adverse Drug Reactions

Risk Communication: Balancing the Benefits and Risks of Drug Treatment

Drug Nomenclature

Pharmacokinetics: Absorption and Distribution

Pharmacokinetics Metabolism and Excretion

Drug Interactions

Drug Development, Evaluation and Safety

Genetic Considerations in Pharmacology

Pharmacokinetic Factors That Modify Drug Action

Paediatric and Geriatric Pharmacology

Poisoning and Envenomation

the Management of Acute Clinical Overdose

Contemporary Drugs of Abuse

Drug Abuse in Sport

General Aspects of Neuropharmacology

Adrenergic Pharmacology

Cholinergic Pharmacology

An Introduction to Chemical Mediators

Histamine and Antihistamines

Prostaglandins and Serotonin

Nitric Oxide and the Endothelins

General concepts of Psychopharmacology

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Medicines Used to Treat Migraine

General Anaesthesia

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Medicines Used to Lower Blood Lipids

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Diuretics and Other Renal Medicines

Topic: Medicines Used to Treat Heart Failure

Medicines Used to Treat Cardiac Dysrhythmia

Fluid and Potassium Imbalances

Antianaemic Agents

Medicines Used to Maintain Gas Exchange

Medicines for Upper Respiratory Tract Conditions

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Enteral and Parenteral Nutrition

Medicines and the Pituitary Gland

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Medicines and the Pancreas

Medicines Affecting the Adrenal Cortex

Medicines and the Gonads

Medicines and Bone Metabolism

Hyperuricaemia and Gout

Obesity and Its Treatment

Introduction to Chemotherapy

Sulfonamides and Trimethoprim

Antibacterial Agents

Antituberculotic and Antileprotic Agents