Question 1

Which of the following statements regarding diabetes insipidus is true?

Accepted Answer

A)  It is affected by the posterior pituitary hormones. 
B)  Urinary output is unusually scant. 
C)  The specific gravity of the urine is 1.005-1.008. 
D)  Serum calcium levels must be monitored. 
A)  It is affected by the posterior pituitary hormones. 
B)  Urinary output is unusually scant. 
C)  The specific gravity of the urine is 1.005-1.008. 
D)  Serum calcium levels must be monitored. A

Question 2

Ergot alkaloids are used to treat prolactin hypersecretion.Their mechanism of action is to:

Accepted Answer

A)  activate dopamine receptors in the pituitary. 
B)  inhibit prolactin-releasing hormone from the pituitary. 
C)  increase the production of growth hormone, which is produced by the same cells in the pituitary gland. 
D)  act on the nipples to desensitise them to stimulation. 
A)  activate dopamine receptors in the pituitary. 
B)  inhibit prolactin-releasing hormone from the pituitary. 
C)  increase the production of growth hormone, which is produced by the same cells in the pituitary gland. 
D)  act on the nipples to desensitise them to stimulation. A

Question 3

Which of the following drugs stimulates gonadotrophin release?

Accepted Answer

A)  The follitropins 
B)  Goserelin 
C)  Clomiphene 
D)  Tetracosactrin 
A)  The follitropins 
B)  Goserelin 
C)  Clomiphene 
D)  Tetracosactrin B

Question 4

Which one of the following statements about oxytocin is correct?

Accepted Answer

A)  There are no clinical uses for oxytocin. 
B)  Oxytocin is believed to have strong serotonergic and $\alpha$-adrenergic activity. 
C)  The anterior pituitary lobe secretes oxytocin. 
D)  Oxytocin promotes breast milk let-down and facilitates placental delivery. 
A)  There are no clinical uses for oxytocin. 
B)  Oxytocin is believed to have strong serotonergic and $\alpha$-adrenergic activity. 
C)  The anterior pituitary lobe secretes oxytocin. 
D)  Oxytocin promotes breast milk let-down and facilitates placental delivery.

Question 5

Which of the following pituitary hormones is a trophic hormone?

Accepted Answer

A)  Prolactin 
B)  Oxytocin 
C)  Luteinising hormone 
D)  Growth hormone 
A)  Prolactin 
B)  Oxytocin 
C)  Luteinising hormone 
D)  Growth hormone

Question 6

Bromocriptine is no longer recommended for inhibition of postpartum lactation.

Accepted Answer

A) True 
 B)False

Question 7

Acromegaly is treated using:

Accepted Answer

A)  lanreotide. 
B)  somatropin. 
C)  lisuride. 
D)  domperidone. 
A)  lanreotide. 
B)  somatropin. 
C)  lisuride. 
D)  domperidone.

Question 8

Somatropin is administered by daily subcutaneous injections to stimulate skeletal and cellular growth.What is a major reason why some individuals fail to respond to treatment?

Accepted Answer

A)  The development of somatropin antibodies by the individual taking the somatropin 
B)  Use of somatropin extracted from the pituitary glands of human cadavers 
C)  Lack of rotation of injection sites 
D)  Use of different brands during a treatment regimen 
A)  The development of somatropin antibodies by the individual taking the somatropin 
B)  Use of somatropin extracted from the pituitary glands of human cadavers 
C)  Lack of rotation of injection sites 
D)  Use of different brands during a treatment regimen

Question 9

When administering somatropin produced from recombinant DNA technology in a young child,it is important to monitor:

Accepted Answer

A)  urinary levels of potassium and sodium. 
B)  for limping. 
C)  serum levels of potassium and sodium. 
D)  for Creutzfeldt-Jakob disease. 
A)  urinary levels of potassium and sodium. 
B)  for limping. 
C)  serum levels of potassium and sodium. 
D)  for Creutzfeldt-Jakob disease.

Question 10

The use of hCG in prepubertal boys can cause:

Accepted Answer

A)  epilepsy. 
B)  stunted long bone growth. 
C)  fluid retention. 
D)  asthma. 
A)  epilepsy. 
B)  stunted long bone growth. 
C)  fluid retention. 
D)  asthma.

Question 11

A serious adverse effect associated with drugs that act like or stimulate release of endogenous gonadotrophin is:

Accepted Answer

A)  low levels of oestrogens in the blood. 
B)  ovarian cysts that may rupture. 
C)  colon cancer. 
D)  gonadal atrophy. 
A)  low levels of oestrogens in the blood. 
B)  ovarian cysts that may rupture. 
C)  colon cancer. 
D)  gonadal atrophy.

Question 12

Which one of the following actions is not associated with high doses of vasopressin?

Accepted Answer

A)  It stimulates sodium excretion. 
B)  It stimulates coagulation. 
C)  It may lower blood pressure. 
D)  It reduces blood loss associated with haemorrhage. 
A)  It stimulates sodium excretion. 
B)  It stimulates coagulation. 
C)  It may lower blood pressure. 
D)  It reduces blood loss associated with haemorrhage.

Question 13

Which group of drugs that act on the pituitary are given to prevent premature ovulation associated with assisted reproduction?

Accepted Answer

A)  Gonadotrophin-releasing hormone antagonists 
B)  Partial oestrogen agonists 
C)  Dopamine agonists 
D)  Gonadotrophins 
A)  Gonadotrophin-releasing hormone antagonists 
B)  Partial oestrogen agonists 
C)  Dopamine agonists 
D)  Gonadotrophins

Question 14

What is the indication for clomiphene?

Accepted Answer

A)  Contraception 
B)  Ovulatory failure 
C)  Treatment of ovarian cancers 
D)  Treatment of growth disorders 
A)  Contraception 
B)  Ovulatory failure 
C)  Treatment of ovarian cancers 
D)  Treatment of growth disorders

Question 15

When using desmopressin for renal function testing,effectiveness of treatment is determined by:

Accepted Answer

A)  measuring blood levels of antidiuretic hormone. 
B)  measuring blood levels of potassium. 
C)  monitoring fluid balance. 
D)  measuring urinary levels of sodium. 
A)  measuring blood levels of antidiuretic hormone. 
B)  measuring blood levels of potassium. 
C)  monitoring fluid balance. 
D)  measuring urinary levels of sodium.

Question 16

In cases of growth hormone hyposecretion,therapy involves the use of:

Accepted Answer

A)  a somatostatin analogue. 
B)  tetracosactrin. 
C)  somatropin. 
D)  the ergot alkaloids. 
A)  a somatostatin analogue. 
B)  tetracosactrin. 
C)  somatropin. 
D)  the ergot alkaloids.

Exam 59: Medicines and the Pituitary Gland

Which of the following statements regarding diabetes insipidus is true?

Ergot alkaloids are used to treat prolactin hypersecretion.Their mechanism of action is to:

Which of the following drugs stimulates gonadotrophin release?

Which one of the following statements about oxytocin is correct?

Which of the following pituitary hormones is a trophic hormone?

Bromocriptine is no longer recommended for inhibition of postpartum lactation.

Acromegaly is treated using:

Somatropin is administered by daily subcutaneous injections to stimulate skeletal and cellular growth.What is a major reason why some individuals fail to respond to treatment?

When administering somatropin produced from recombinant DNA technology in a young child,it is important to monitor:

The use of hCG in prepubertal boys can cause:

A serious adverse effect associated with drugs that act like or stimulate release of endogenous gonadotrophin is:

Which one of the following actions is not associated with high doses of vasopressin?

Which group of drugs that act on the pituitary are given to prevent premature ovulation associated with assisted reproduction?

What is the indication for clomiphene?

When using desmopressin for renal function testing,effectiveness of treatment is determined by:

In cases of growth hormone hyposecretion,therapy involves the use of:

Sociocultural Aspects

Health Professionals and the Law

Ethical Issues

the Roles and Responsibilities of Health Professionals in Medicine Adherence, Education and Advocacy

the Roles and Responsibilities of Health Professionals in Medicine Management

Medicine Formulations, Storage and Routes of Administration

the Clinical Decision-making Process

Medicine Administration Strategies and Documentation

Medication Errors

Management of Common Adverse Drug Reactions

Risk Communication: Balancing the Benefits and Risks of Drug Treatment

Drug Nomenclature

Pharmacokinetics: Absorption and Distribution

Pharmacokinetics Metabolism and Excretion

Drug Interactions

Pharmacodynamics

Drug Development, Evaluation and Safety

Genetic Considerations in Pharmacology

Pharmacokinetic Factors That Modify Drug Action

Paediatric and Geriatric Pharmacology

Poisoning and Envenomation

the Management of Acute Clinical Overdose

Contemporary Drugs of Abuse

Drug Abuse in Sport

General Aspects of Neuropharmacology

Adrenergic Pharmacology

Cholinergic Pharmacology

An Introduction to Chemical Mediators

Histamine and Antihistamines

Prostaglandins and Serotonin

Nitric Oxide and the Endothelins

General concepts of Psychopharmacology

Antipsychotics

Anxiolytics and Hypnotics

Antidepressants and Mood Stabilisers

Medicines Used in Neurodegenerative Disorders

Antiseizure Agents and Muscle Relaxants

Central Nervous System Stimulants

Opioid Analgesics

Anti-inflammatory, Antipyretic and Non-opioid Analgesic Agents

Medicines Used to Treat Migraine

General Anaesthesia

Local Anesthesia

Medicines Used to Lower Blood Lipids

Antihypertensive Agents

Medicines Used to Promote Tissue Perfusion

Antithrombotic, Fibrinolytic and Haemostatic Agents

Diuretics and Other Renal Medicines

Topic: Medicines Used to Treat Heart Failure

Medicines Used to Treat Cardiac Dysrhythmia

Fluid and Potassium Imbalances

Antianaemic Agents

Medicines Used to Maintain Gas Exchange

Medicines for Upper Respiratory Tract Conditions

Upper Gastrointestinal Tract Medicines

Lower Castrointestinal Tract Medicines

Antiemetic Agents

Enteral and Parenteral Nutrition

Medicines and the Thyroid

Medicines and the Pancreas

Medicines Affecting the Adrenal Cortex

Medicines and the Gonads

Medicines and Bone Metabolism