Question 1

Which of the following is not a property of prions?

Accepted Answer

A) Contain single-stranded DNA 
B) Transmissible between different species 
C) Resistant to proteases 
D) Spongiform encephalopathy 
E) Are proteins 
A) Contain single-stranded DNA 
B) Transmissible between different species 
C) Resistant to proteases 
D) Spongiform encephalopathy 
E) Are proteins

Question 2

Which of the following is not a route used by bacteria for central nervous system (CNS)infections?

Accepted Answer

A) From infected sinuses and mastoid air spaces 
B) From the respiratory system across a fracture at the base of the skull 
C) Via peripheral sensory nerves 
D) From the bloodstream across the blood-brain barrier 
E) Via anatomical defects in structures encasing the CNS 
A) From infected sinuses and mastoid air spaces 
B) From the respiratory system across a fracture at the base of the skull 
C) Via peripheral sensory nerves 
D) From the bloodstream across the blood-brain barrier 
E) Via anatomical defects in structures encasing the CNS

Question 3

Compare abortive to paralytic polio in relation to the following statement: It is essentially nonexistent in developed countries.

Accepted Answer

A) Abortive 
B) Paralytic 
C) Both abortive and paralytic 
D) Neither abortive or paralytic 
A) Abortive 
B) Paralytic 
C) Both abortive and paralytic 
D) Neither abortive or paralytic

Question 4

The _____ form of rabies occurs in wild animals.

Accepted Answer

A) Urban 
B) Zoonotic 
C) Sylvatic 
D) Encephalitic 
A) Urban 
B) Zoonotic 
C) Sylvatic 
D) Encephalitic

Question 5

Honey should not be given to infants under the age of 1 year because it may contain spores of _____ that,in severe cases,may lead to paralysis.

Accepted Answer

A) Bacillus subtilis 
B) Clostridium botulinum 
C) Clostridium tetani 
D) Streptomyces spp. 
A) Bacillus subtilis 
B) Clostridium botulinum 
C) Clostridium tetani 
D) Streptomyces spp.

Question 6

Which of the following does not cause chronic meningitis?

Accepted Answer

A) Rabies virus 
B) Toxoplasma gondii 
C) Cryptococcus neoformans 
D) Mycobacterium tuberculosis 
E) Treponema pallidum 
A) Rabies virus 
B) Toxoplasma gondii 
C) Cryptococcus neoformans 
D) Mycobacterium tuberculosis 
E) Treponema pallidum

Question 7

Exotoxins produced by _____ have an affinity for the central nervous system.

Accepted Answer

A) Neisseria meningitidis 
B) Clostridium botulinum 
C) Salmonella enteritidis 
D) Streptococcus pneumoniae 
E) Haemophilus influenzae type b 
A) Neisseria meningitidis 
B) Clostridium botulinum 
C) Salmonella enteritidis 
D) Streptococcus pneumoniae 
E) Haemophilus influenzae type b

Question 8

Which of the following is a mismatched pair?

Accepted Answer

A) Haemophilus influenzae type b: acute purulent meningitis 
B) Clostridium tetani: neurogenic toxin 
C) Botulinum toxin: increased synthesis and release of acetylcholine 
D) Measles: Subacute sclerosing panencephalitis 
E) Rabies virus: Negri bodies 
A) Haemophilus influenzae type b: acute purulent meningitis 
B) Clostridium tetani: neurogenic toxin 
C) Botulinum toxin: increased synthesis and release of acetylcholine 
D) Measles: Subacute sclerosing panencephalitis 
E) Rabies virus: Negri bodies

Question 9

All of the following are characteristic of most cases of aseptic meningitis except

Accepted Answer

A) More than 90% of cases are caused by enterovirus 
B) Self-limiting with symptoms lasting 7-10 days 
C) High fever, stiff neck, and headache 
D) Diagnosis requires cerebrospinal fluid sample 
E) Treated with antibiotics 
A) More than 90% of cases are caused by enterovirus 
B) Self-limiting with symptoms lasting 7-10 days 
C) High fever, stiff neck, and headache 
D) Diagnosis requires cerebrospinal fluid sample 
E) Treated with antibiotics

Question 10

Cerebrospinal fluid is located in the

Accepted Answer

A) Blood vessels surrounding the cerebrum 
B) Subarachnoid space 
C) Dura mater 
D) Spinal cord 
E) Cerebrum 
A) Blood vessels surrounding the cerebrum 
B) Subarachnoid space 
C) Dura mater 
D) Spinal cord 
E) Cerebrum

Question 11

Answer true or false to the reason given in the following statement: Because there is no room for swelling of the nervous tissue enclosed by the skull,any pathology that occurs in the brain and results in increased intracranial pressure can have disastrous and potentially lethal consequences.

Accepted Answer

A) True 
 B)False

Question 12

Identify which of the following persistent infections of the central nervous system is a mismatched pair.

Accepted Answer

A) Human immunodeficiency virus: AIDS dementia complex 
B) Progressive panencephalitis: rubella 
C) Measles: subacute sclerosing panencephalitis 
D) Kuru: prions 
E) Creutzfeldt-Jacob disease: persistent enterovirus infection 
A) Human immunodeficiency virus: AIDS dementia complex 
B) Progressive panencephalitis: rubella 
C) Measles: subacute sclerosing panencephalitis 
D) Kuru: prions 
E) Creutzfeldt-Jacob disease: persistent enterovirus infection

Question 13

Which of the following causes primary amebic meningoencephalitis?

Accepted Answer

A) Prions 
B) Trypanosomes 
C) Cryptococcus neoformans 
D) Naegleria spp. 
E) Giardia duodenalis 
A) Prions 
B) Trypanosomes 
C) Cryptococcus neoformans 
D) Naegleria spp. 
E) Giardia duodenalis

Question 14

Clostridium tetani is transmitted by

Accepted Answer

A) The ingestion of preformed toxin in tainted food 
B) Close or prolonged contact with infected individuals 
C) The bite of an arthropod vector 
D) Blood transfusion 
E) Exposure of a wound to contaminated soil 
A) The ingestion of preformed toxin in tainted food 
B) Close or prolonged contact with infected individuals 
C) The bite of an arthropod vector 
D) Blood transfusion 
E) Exposure of a wound to contaminated soil

Question 15

Which of the following is not associated with bacterial meningitis?

Accepted Answer

A) Haemophilus influenzae 
B) Clostridium botulinum 
C) Neisseria meningitidis 
D) Streptococcus pneumoniae 
E) Staphylococcus aureus 
A) Haemophilus influenzae 
B) Clostridium botulinum 
C) Neisseria meningitidis 
D) Streptococcus pneumoniae 
E) Staphylococcus aureus

Question 16

Which of the following statements regarding cryptococcosis is true?

Accepted Answer

A)  Cryptococcosis is caused by an un-encapsulated form of yeast called Cryptococcus neoformans 
B)  Cryptococcosis is common in AIDS patients and in people with defects in cell-mediated immunity 
C)  Cryptococcal meningitis is transmitted by arthropod vectors 
D)  C. neoformans causes acute polyneuritis 
A)  Cryptococcosis is caused by an un-encapsulated form of yeast called Cryptococcus neoformans 
B)  Cryptococcosis is common in AIDS patients and in people with defects in cell-mediated immunity 
C)  Cryptococcal meningitis is transmitted by arthropod vectors 
D)  C. neoformans causes acute polyneuritis

Question 17

Which of the following is not an example of an arbovirus?

Accepted Answer

A) West Nile virus 
B) Saint Louis encephalitis 
C) Eastern equine encephalitis 
D) Western equine encephalitis 
E) Rabies virus 
A) West Nile virus 
B) Saint Louis encephalitis 
C) Eastern equine encephalitis 
D) Western equine encephalitis 
E) Rabies virus

Question 18

Compare abortive to paralytic polio in relation to the following statement: It can be prevented by vaccination.

Accepted Answer

A) Abortive 
B) Paralytic 
C) Both abortive and paralytic 
D) Neither abortive or paralytic 
A) Abortive 
B) Paralytic 
C) Both abortive and paralytic 
D) Neither abortive or paralytic

Question 19

A viral infection isolated in the meninges without involvement of neural tissue is referred to as

Accepted Answer

A) Chronic meningitis 
B) Purulent meningitis 
C) Encephalitis 
D) Paralytic poliomyelitis 
E) Aseptic meningitis 
A) Chronic meningitis 
B) Purulent meningitis 
C) Encephalitis 
D) Paralytic poliomyelitis 
E) Aseptic meningitis

Question 20

Answer true or false to the reason given in the following statement: Poliomyelitis is essentially nonexistent in developed countries because of intensive supportive care.

Accepted Answer

A) True 
 B)False

Exam 24: Infections of the Central Nervous System

Which of the following is not a property of prions?

Which of the following is not a route used by bacteria for central nervous system (CNS)infections?

Compare abortive to paralytic polio in relation to the following statement: It is essentially nonexistent in developed countries.

The _____ form of rabies occurs in wild animals.

Honey should not be given to infants under the age of 1 year because it may contain spores of _____ that,in severe cases,may lead to paralysis.

Which of the following does not cause chronic meningitis?

Exotoxins produced by _____ have an affinity for the central nervous system.

Which of the following is a mismatched pair?

All of the following are characteristic of most cases of aseptic meningitis except

Cerebrospinal fluid is located in the

Answer true or false to the reason given in the following statement: Because there is no room for swelling of the nervous tissue enclosed by the skull,any pathology that occurs in the brain and results in increased intracranial pressure can have disastrous and potentially lethal consequences.

Identify which of the following persistent infections of the central nervous system is a mismatched pair.

Which of the following causes primary amebic meningoencephalitis?

Clostridium tetani is transmitted by

Which of the following is not associated with bacterial meningitis?

Which of the following statements regarding cryptococcosis is true?

Which of the following is not an example of an arbovirus?

Compare abortive to paralytic polio in relation to the following statement: It can be prevented by vaccination.

A viral infection isolated in the meninges without involvement of neural tissue is referred to as

Answer true or false to the reason given in the following statement: Poliomyelitis is essentially nonexistent in developed countries because of intensive supportive care.

What is Microbiology and Why Does it Matter?

Fundamental Chemistry for Microbiology

Essentials of Metabolism

An Introduction to Cell Structure and Host-Pathogen Relationships

Requirements for Infection

Transmission of Infection, the Compromised Host, Epidemiology, and Diagnosing Infections

Principles of Disease

Emerging and Re-Emerging Infectious Disease

The Clinical Significance of Bacterial Anatomy

Bacterial Growth

Microbial Genetics and Infectious Disease

The Structure and Infection Cycle of Viruses

Viral Infection

Parasitic and Fungal Infections

The Innate Immune Response

The Adaptive Immune Response

Failures of the Immune Response

Control of Microbial Growth with Disinfectants and Antiseptics

Antibiotics and Antimicrobial Drugs

Antibiotic Resistance

Infections of the Respiratory System

Infections of the Digestive System

Infections of the Genitourinary System

Infections of the Blood and Lymph

Infections of the Skin and Eyes

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