Question 1

Describe the three ways in which antibodies function to protect a host from pathogens.

Accepted Answer

Antibodies function in three main ways:

Question 2

Which of the following is incorrectly matched?

Accepted Answer

A) Helper T cells: CD8 
B) MHC class I: cytotoxic T cells 
C) Cytotoxic T cells: CD8 
D) MHC class II: antigen derived from vesicular compartments 
E) Humoral immune response: B cells 
A) Helper T cells: CD8 
B) MHC class I: cytotoxic T cells 
C) Cytotoxic T cells: CD8 
D) MHC class II: antigen derived from vesicular compartments 
E) Humoral immune response: B cells

Question 3

What protects the mucosal surfaces of the gastrointestinal and respiratory tracts by inhibiting the adherence of pathogens to host cell surfaces?

Accepted Answer

A) IgA 
B) IgD 
C) IgE 
D) IgG 
E) IgM 
A) IgA 
B) IgD 
C) IgE 
D) IgG 
E) IgM

Question 4

All of the following are examples of chemical interactions used to facilitate the binding of antigen to antibody except

Accepted Answer

A) Hydrogen bonds 
B) Electrostatic forces 
C) Peptide bonds 
D) Hydrophobic forces 
A) Hydrogen bonds 
B) Electrostatic forces 
C) Peptide bonds 
D) Hydrophobic forces

Question 5

Explain why dendritic cells are considered "watch dogs" for pathogens.

Accepted Answer

Dendritic cells are resident in most tis

Question 6

Compare and contrast the heavy and light chains of a soluble antibody.Which contains part of the antigen-binding site?

Accepted Answer

A) Heavy chain 
B) Light chain 
C) Both heavy and light chains 
D) Neither of the heavy or light chains 
A) Heavy chain 
B) Light chain 
C) Both heavy and light chains 
D) Neither of the heavy or light chains

Question 7

Which of the following is a mismatched pair?

Accepted Answer

A) Lymphocytes: T, B, and NK cells 
B) Dendritic cells: antigen processing and presentation 
C) Activated B cells: plasma cells 
D) Tolerance: foreign antigens 
E) Cytotoxic T cells: kill virally infected cells 
A) Lymphocytes: T, B, and NK cells 
B) Dendritic cells: antigen processing and presentation 
C) Activated B cells: plasma cells 
D) Tolerance: foreign antigens 
E) Cytotoxic T cells: kill virally infected cells

Question 8

The movement of antibodies across epithelial barriers is called

Accepted Answer

A) Transcytosis 
B) Secretion 
C) Dimerization 
D) poly-Ig transport 
E) Vesicular exocytosis 
A) Transcytosis 
B) Secretion 
C) Dimerization 
D) poly-Ig transport 
E) Vesicular exocytosis

Question 9

Explain the key differences between superantigens and conventional antigens recognized by T cells.Provide an example of a super antigen.

Accepted Answer

Conventional antigens bind to MHC molecu

Question 10

Explain the difference between GALT,MALT,and BALT.Describe what they have in common.

Accepted Answer

GALT,MALT,and BALT are lymphoid tissues

Question 11

Compare and contrast the heavy and light chains of a soluble antibody.Which part contains sulfide?

Accepted Answer

A) Heavy chain 
B) Light chain 
C) Both heavy and light chains 
D) Neither of the heavy or light chains 
A) Heavy chain 
B) Light chain 
C) Both heavy and light chains 
D) Neither of the heavy or light chains

Question 12

Compare and contrast the heavy and light chains of a soluble antibody.Which part contains the binding site for complement protein C1?

Accepted Answer

A) Heavy chain 
B) Light chain 
C) Both heavy and light chains 
D) Neither of the heavy or light chains 
A) Heavy chain 
B) Light chain 
C) Both heavy and light chains 
D) Neither of the heavy or light chains

Question 13

The production of effector T cells is made possible by all of the following except

Accepted Answer

A) Macrophages 
B) Mast cells 
C) Dendritic cells 
D) B cells 
A) Macrophages 
B) Mast cells 
C) Dendritic cells 
D) B cells

Question 14

The B cell antigen receptor is called a(n)

Accepted Answer

A) Co-receptor 
B) Immunoglobulin 
C) Major histocompatibility complex 
D) Secretory piece 
E) Memory molecule 
A) Co-receptor 
B) Immunoglobulin 
C) Major histocompatibility complex 
D) Secretory piece 
E) Memory molecule

Question 15

Cytotoxic T cells use all of the following to destroy target cells except

Accepted Answer

A) Granulysin 
B) Perforin 
C) Granzyme 
D) Histamine 
A) Granulysin 
B) Perforin 
C) Granzyme 
D) Histamine

Question 16

The location on the immunoglobulin that contributes to the unique antigen-binding site is referred to as the

Accepted Answer

A) Epitope 
B) Variable region 
C) J chain 
D) Superantigen 
A) Epitope 
B) Variable region 
C) J chain 
D) Superantigen

Question 17

T lymphocytes mature in the

Accepted Answer

A) Thyroid 
B) Bone marrow 
C) Spleen 
D) Lymph nodes 
E) Thymus 
A) Thyroid 
B) Bone marrow 
C) Spleen 
D) Lymph nodes 
E) Thymus

Question 18

Suppose the epithelial cells did not internalize their poly-Ig receptors,which of the following would you predict will be false?

Accepted Answer

A) IgA would bind to the basal side of the cell 
B) IgA would not be internalised by the cell 
C) IgA would not be transferred to the apical side of the cell 
D) IgA would not be secreted into the lumen 
E) The person with this defect would experience the same or fewer intestinal diseases 
A) IgA would bind to the basal side of the cell 
B) IgA would not be internalised by the cell 
C) IgA would not be transferred to the apical side of the cell 
D) IgA would not be secreted into the lumen 
E) The person with this defect would experience the same or fewer intestinal diseases

Question 19

Which of the following is a mismatched pair?

Accepted Answer

A) CD8 T cells: class I MHC molecules 
B) Cellular adaptive immune responses: T cells 
C) TH2 cells: parasites 
D) Humoral immune responses: B cells 
E) CD4 T cells: class I MHC molecules 
A) CD8 T cells: class I MHC molecules 
B) Cellular adaptive immune responses: T cells 
C) TH2 cells: parasites 
D) Humoral immune responses: B cells 
E) CD4 T cells: class I MHC molecules

Question 20

A(n)_____ is any foreign substance that provokes an immune response.

Accepted Answer

A) Mitogen 
B) Immunoglobulin 
C) Tolerate 
D) Antigen 
E) Androgen 
A) Mitogen 
B) Immunoglobulin 
C) Tolerate 
D) Antigen 
E) Androgen

Exam 16: The Adaptive Immune Response

Describe the three ways in which antibodies function to protect a host from pathogens.

Which of the following is incorrectly matched?

What protects the mucosal surfaces of the gastrointestinal and respiratory tracts by inhibiting the adherence of pathogens to host cell surfaces?

All of the following are examples of chemical interactions used to facilitate the binding of antigen to antibody except

Explain why dendritic cells are considered "watch dogs" for pathogens.

Compare and contrast the heavy and light chains of a soluble antibody.Which contains part of the antigen-binding site?

Which of the following is a mismatched pair?

The movement of antibodies across epithelial barriers is called

Explain the key differences between superantigens and conventional antigens recognized by T cells.Provide an example of a super antigen.

Explain the difference between GALT,MALT,and BALT.Describe what they have in common.

Compare and contrast the heavy and light chains of a soluble antibody.Which part contains sulfide?

Compare and contrast the heavy and light chains of a soluble antibody.Which part contains the binding site for complement protein C1?

The production of effector T cells is made possible by all of the following except

The B cell antigen receptor is called a(n)

Cytotoxic T cells use all of the following to destroy target cells except

The location on the immunoglobulin that contributes to the unique antigen-binding site is referred to as the

T lymphocytes mature in the

Suppose the epithelial cells did not internalize their poly-Ig receptors,which of the following would you predict will be false?

Which of the following is a mismatched pair?

A(n)_____ is any foreign substance that provokes an immune response.

What is Microbiology and Why Does it Matter?

Fundamental Chemistry for Microbiology

Essentials of Metabolism

An Introduction to Cell Structure and Host-Pathogen Relationships

Requirements for Infection

Transmission of Infection, the Compromised Host, Epidemiology, and Diagnosing Infections

Principles of Disease

Emerging and Re-Emerging Infectious Disease

The Clinical Significance of Bacterial Anatomy

Bacterial Growth

Microbial Genetics and Infectious Disease

The Structure and Infection Cycle of Viruses

Viral Infection

Parasitic and Fungal Infections

The Innate Immune Response

Failures of the Immune Response

Control of Microbial Growth with Disinfectants and Antiseptics

Antibiotics and Antimicrobial Drugs

Antibiotic Resistance

Infections of the Respiratory System

Infections of the Digestive System

Infections of the Genitourinary System

Infections of the Central Nervous System

Infections of the Blood and Lymph

Infections of the Skin and Eyes

Filters