Question 1

Answer true or false to the following statement: The skin is free of microorganism.

Accepted Answer

A) True 
 B)False

Question 2

Answer true or false to the following statement: Chemokines attract defensive cells to the site of an infection.

Accepted Answer

A) True 
 B)False

Question 3

Explain the difference between a complete blood count (CBC)and a differential analysis.Why would it be helpful to carry out these tests during the course of an infection?

Accepted Answer

A complete blood count (CBC)reports the

Question 4

Answer true or false to the following statement: TLR-5 binds to LPS.

Accepted Answer

A) True 
 B)False

Question 5

Which of the following includes growth hormones?

Accepted Answer

A) Hematopoietins 
B) Chemokines 
C) Both hematopoietins and chemokines 
D) None of the choices 
A) Hematopoietins 
B) Chemokines 
C) Both hematopoietins and chemokines 
D) None of the choices

Question 6

Answer true or false to the following statement: Bacteria buried in food particles are protected from stomach acids.

Accepted Answer

A) True 
 B)False

Question 7

Which of the following is an effect of proteins C3a and C5a?

Accepted Answer

A) Activation of the classical pathway 
B) Histamine release 
C) Opsonization 
A) Activation of the classical pathway 
B) Histamine release 
C) Opsonization

Question 8

Answer true or false to the following statement: The epidermis is impenetrable to most microorganisms.

Accepted Answer

A) True 
 B)False

Question 9

Identify three types of resident macrophage.What are the different functions of macrophages during immune responses?

Accepted Answer

Resident macrophages maintain their posi

Question 10

Which of the following is a mismatched pair?

Accepted Answer

A) Microglial cells: spleen 
B) Liver: Kupffer cells 
C) Epidermis: dendritic cells 
D) Blood: monocytes 
E) Lung: alveolar macrophages 
A) Microglial cells: spleen 
B) Liver: Kupffer cells 
C) Epidermis: dendritic cells 
D) Blood: monocytes 
E) Lung: alveolar macrophages

Question 11

What happens if the bone marrow reserve of neutrophils is depleted during a long-lasting infection?

Accepted Answer

A) Immature neutrophils are exported from the bone marrow, but they are not as effective as mature neutrophils 
B) Tissue macrophages replicate at sites of infection to make up for the numbers needed 
C) The adaptive immune response must compensate for the loss 
D) The lifespan of previously exported neutrophils is extended 
A) Immature neutrophils are exported from the bone marrow, but they are not as effective as mature neutrophils 
B) Tissue macrophages replicate at sites of infection to make up for the numbers needed 
C) The adaptive immune response must compensate for the loss 
D) The lifespan of previously exported neutrophils is extended

Question 12

What is the purpose of the mucociliary escalator? Explain the mechanism by which it functions.

Accepted Answer

Ciliated cells and goblet cells line the

Question 13

Tears consist of all of the following except

Accepted Answer

A) Sebum 
B) Lipocalin 
C) Lysozyme 
D) IgA 
A) Sebum 
B) Lipocalin 
C) Lysozyme 
D) IgA

Question 14

The interaction between natural killer (NK)cells and macrophages amplifies the innate immune response.Rearrange the following into the order of events during this amplification.Which is the second event?

Accepted Answer

A) Macrophage production of cytokines TNF and IL-12 increases 
B) Increased production of IL-2 by NK cells 
C) NK cells produce gamma interferon (IFN-?) 
D) Proliferation of NK cells 
A) Macrophage production of cytokines TNF and IL-12 increases 
B) Increased production of IL-2 by NK cells 
C) NK cells produce gamma interferon (IFN-?) 
D) Proliferation of NK cells

Question 15

Answer true or false to the following statement: Endogenous pyrogens are pathogen-specific inducers of fever.

Accepted Answer

A) True 
 B)False

Question 16

Answer true or false to the following statement: The adaptive immune response is nonspecific and lacks memory.

Accepted Answer

A) True 
 B)False

Question 17

The interaction between natural killer (NK)cells and macrophages amplifies the innate immune response.Rearrange the following into the order of events during this amplification.Which is the third event?

Accepted Answer

A) Macrophage production of cytokines TNF and IL-12 increases 
B) Increased production of IL-2 by NK cells 
C) NK cells produce gamma interferon (IFN-?) 
D) Proliferation of NK cells 
A) Macrophage production of cytokines TNF and IL-12 increases 
B) Increased production of IL-2 by NK cells 
C) NK cells produce gamma interferon (IFN-?) 
D) Proliferation of NK cells

Question 18

The cells of the epidermis contain _____,a protein that provides strength and partial waterproofing to the outer layer of skin.

Accepted Answer

A) Lysozyme 
B) Sebum 
C) Transferrin 
D) Prostaglandin 
E) Keratin 
A) Lysozyme 
B) Sebum 
C) Transferrin 
D) Prostaglandin 
E) Keratin

Question 19

Which of the following are acute-phase proteins?

Accepted Answer

A) Mannose-binding protein 
B) Leukotrienes 
C) C-reactive protein 
D) Mannose-binding protein and C-reactive protein 
E) Mannose-binging protein, leukotrienes, and C-reactive protein 
A) Mannose-binding protein 
B) Leukotrienes 
C) C-reactive protein 
D) Mannose-binding protein and C-reactive protein 
E) Mannose-binging protein, leukotrienes, and C-reactive protein

Question 20

The interaction between natural killer (NK)cells and macrophages amplifies the innate immune response.Rearrange the following into the order of events during this amplification.Which is the first event?

Accepted Answer

A) Macrophage production of cytokines TNF and IL-12 increases 
B) Increased production of IL-2 by NK cells 
C) NK cells produce gamma interferon (IFN-?) 
D) Proliferation of NK cells 
A) Macrophage production of cytokines TNF and IL-12 increases 
B) Increased production of IL-2 by NK cells 
C) NK cells produce gamma interferon (IFN-?) 
D) Proliferation of NK cells

Exam 15: The Innate Immune Response

Answer true or false to the following statement: The skin is free of microorganism.

Answer true or false to the following statement: Chemokines attract defensive cells to the site of an infection.

Explain the difference between a complete blood count (CBC)and a differential analysis.Why would it be helpful to carry out these tests during the course of an infection?

Answer true or false to the following statement: TLR-5 binds to LPS.

Which of the following includes growth hormones?

Answer true or false to the following statement: Bacteria buried in food particles are protected from stomach acids.

Which of the following is an effect of proteins C3a and C5a?

Answer true or false to the following statement: The epidermis is impenetrable to most microorganisms.

Identify three types of resident macrophage.What are the different functions of macrophages during immune responses?

Which of the following is a mismatched pair?

What happens if the bone marrow reserve of neutrophils is depleted during a long-lasting infection?

What is the purpose of the mucociliary escalator? Explain the mechanism by which it functions.

Tears consist of all of the following except

The interaction between natural killer (NK)cells and macrophages amplifies the innate immune response.Rearrange the following into the order of events during this amplification.Which is the second event?

Answer true or false to the following statement: Endogenous pyrogens are pathogen-specific inducers of fever.

Answer true or false to the following statement: The adaptive immune response is nonspecific and lacks memory.

The interaction between natural killer (NK)cells and macrophages amplifies the innate immune response.Rearrange the following into the order of events during this amplification.Which is the third event?

The cells of the epidermis contain _____,a protein that provides strength and partial waterproofing to the outer layer of skin.

Which of the following are acute-phase proteins?

The interaction between natural killer (NK)cells and macrophages amplifies the innate immune response.Rearrange the following into the order of events during this amplification.Which is the first event?

What is Microbiology and Why Does it Matter?

Fundamental Chemistry for Microbiology

Essentials of Metabolism

An Introduction to Cell Structure and Host-Pathogen Relationships

Requirements for Infection

Transmission of Infection, the Compromised Host, Epidemiology, and Diagnosing Infections

Principles of Disease

Emerging and Re-Emerging Infectious Disease

The Clinical Significance of Bacterial Anatomy

Bacterial Growth

Microbial Genetics and Infectious Disease

The Structure and Infection Cycle of Viruses

Viral Infection

Parasitic and Fungal Infections

The Adaptive Immune Response

Failures of the Immune Response

Control of Microbial Growth with Disinfectants and Antiseptics

Antibiotics and Antimicrobial Drugs

Antibiotic Resistance

Infections of the Respiratory System

Infections of the Digestive System

Infections of the Genitourinary System

Infections of the Central Nervous System

Infections of the Blood and Lymph

Infections of the Skin and Eyes

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