Question 1

To prevent tolerance,prophylactic nitrates should be given with at least a(n)

Accepted Answer

A) week off every month. 
B) day off every week. 
C) 8- to 12-hour "vacation" every day. 
D) 1 hour "vacation" every 12 hours. 
A) week off every month. 
B) day off every week. 
C) 8- to 12-hour "vacation" every day. 
D) 1 hour "vacation" every 12 hours.

Question 2

Which of the following statements is true of ezetimibe?

Accepted Answer

A) It is an HMG Co-A reductase inhibitor. 
B) This drug decreases total cholesterol,HDL cholesterol,and decreases HDL cholesterol levels. 
C) It is currently available in combination with simvastatin or atorvastatin to treat cholesterol with two different mechanisms of action. 
D) Ezetimibe/simvastatin has been found to lower low-density lipoprotein (LDL)cholesterol and has a marked effect on plaque buildup. 
A) It is an HMG Co-A reductase inhibitor. 
B) This drug decreases total cholesterol,HDL cholesterol,and decreases HDL cholesterol levels. 
C) It is currently available in combination with simvastatin or atorvastatin to treat cholesterol with two different mechanisms of action. 
D) Ezetimibe/simvastatin has been found to lower low-density lipoprotein (LDL)cholesterol and has a marked effect on plaque buildup.

Question 3

Which of the following classes of antiarrhythmics is associated with gingival enlargement?

Accepted Answer

A) Amiodarone 
B) Calcium channel blockers 
C) Disopyramide 
D) Procainamide 
E) Quinidine 
A) Amiodarone 
B) Calcium channel blockers 
C) Disopyramide 
D) Procainamide 
E) Quinidine

Question 4

a-Methyldopa and clonidine act in the central nervous system (CNS)as a-adrenergic antagonists.

Accepted Answer

A) True 
 B)False

Question 5

Which is the treatment of choice for the treatment of heart failure (HF)?

Accepted Answer

A) Diuretics 
B) Angiotensin-converting enzyme inhibitors 
C) Angiotensin receptor blockers 
D) Angiotensin II receptor neprilysin inhibitor 
E) If channel inhibitor 
A) Diuretics 
B) Angiotensin-converting enzyme inhibitors 
C) Angiotensin receptor blockers 
D) Angiotensin II receptor neprilysin inhibitor 
E) If channel inhibitor

Question 6

There is a danger of _____ if the dose of anticoagulant is too small.

Accepted Answer

A) embolism 
B) hemorrhage 
C) chronic obstructive pulmonary disease 
D) angina 
A) embolism 
B) hemorrhage 
C) chronic obstructive pulmonary disease 
D) angina

Question 7

Which of the following drugs is a direct inhibitor of thrombin?

Accepted Answer

A) Rivaroxaban (Xarelto) 
B) Dabigatran (Pradaxa) 
C) Clopidogrel (Plavix) 
D) Ticlopidine (Ticlid) 
E) Alteplase (Activase) 
A) Rivaroxaban (Xarelto) 
B) Dabigatran (Pradaxa) 
C) Clopidogrel (Plavix) 
D) Ticlopidine (Ticlid) 
E) Alteplase (Activase)

Question 8

The _____ has the fastest rate of depolarization and therefore directs all the other cells of the heart.

Accepted Answer

A) sinoatrial (S
A) node 
B) atrioventricular (AV)node 
C) bundle of His 
D) Purkinje fibers 
A) sinoatrial (S
A) node 
B) atrioventricular (AV)node 
C) bundle of His 
D) Purkinje fibers

Question 9

Entresto works primarily by (Select all that apply. )

Accepted Answer

A) stimulating diuresis. 
B) blocking angiotensin receptors. 
C) blocking calcium channels. 
D) inhibiting neprilysin. 
A) stimulating diuresis. 
B) blocking angiotensin receptors. 
C) blocking calcium channels. 
D) inhibiting neprilysin.

Question 10

Which of the following statements is true regarding hypertension?

Accepted Answer

A) High blood pressure eventually damages internal organs. 
B) Complications of hypertension are greatly increased with concomitant smoking. 
C) In most cases of hypertension,the cause can be identified and associated with a specific disease process. 
D) Both A and B are true. 
E) Both B and C are true. 
A) High blood pressure eventually damages internal organs. 
B) Complications of hypertension are greatly increased with concomitant smoking. 
C) In most cases of hypertension,the cause can be identified and associated with a specific disease process. 
D) Both A and B are true. 
E) Both B and C are true.

Question 11

Which of the following categories of agents may be used to treat both hypertension and benign prostatic hypertrophy?

Accepted Answer

A) Diuretic agents 
B) b-Adrenergic blocking agents 
C) A₁-Adrenergic blocking agents 
D) Calcium channel blocking agents 
A) Diuretic agents 
B) b-Adrenergic blocking agents 
C) A₁-Adrenergic blocking agents 
D) Calcium channel blocking agents

Question 12

The use of nitroglycerin (NTG)is contraindicated if sildenafil (Viagra)has been administered within 24 hours.This is because the NTG-sildenafil combination can precipitate a hypertensive crisis.

Accepted Answer

A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement is false,the second is true. 
A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement is false,the second is true.

Question 13

How long should a person who has had a myocardial infarction wait before receiving dental care?

Accepted Answer

A) 2 weeks 
B) 2 months 
C) 6 months 
D) 12 months 
E) 24 months 
A) 2 weeks 
B) 2 months 
C) 6 months 
D) 12 months 
E) 24 months

Question 14

Some studies have found that the presence of periodontal disease predicts an increase in morbidity and mortality resulting from cardiovascular disease.Other studies have failed to show a relationship.

Accepted Answer

A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement is false,the second is true. 
A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement is false,the second is true.

Question 15

Calcium channel blockers may be used to treat which of the following? (Select all that apply. )

Accepted Answer

A) Angina 
B) Cardiac arrhythmia 
C) Hypertension 
D) Hyperlipidemia 
A) Angina 
B) Cardiac arrhythmia 
C) Hypertension 
D) Hyperlipidemia

Question 16

Niacin works by

Accepted Answer

A) inhibiting HMG-CoA reductase. 
B) inhibiting the intestinal absorption of cholesterol. 
C) inhibiting the secretion of very-low-density lipoproteins (VLDLs)without accumulation of triglycerides in the liver. 
D) increasing lipolysis of triglycerides,decreasing lipolysis in adipose tissue,and inhibiting secretions of VLDLs from the liver. 
A) inhibiting HMG-CoA reductase. 
B) inhibiting the intestinal absorption of cholesterol. 
C) inhibiting the secretion of very-low-density lipoproteins (VLDLs)without accumulation of triglycerides in the liver. 
D) increasing lipolysis of triglycerides,decreasing lipolysis in adipose tissue,and inhibiting secretions of VLDLs from the liver.

Question 17

a-Methyldopa (Aldomet)and clonidine (Catapres [TTS])act in the central nervous system (CNS)as

Accepted Answer

A) alpha-adrenergic blocking agents. 
B) alpha-adrenergic agonists. 
C) beta-adrenergic blocking agents. 
D) beta-blockers with alpha-blocking activity. 
A) alpha-adrenergic blocking agents. 
B) alpha-adrenergic agonists. 
C) beta-adrenergic blocking agents. 
D) beta-blockers with alpha-blocking activity.

Question 18

One can prevent an attack of angina pectoris by administering nitrous oxide.

Accepted Answer

A) True 
 B)False

Question 19

Patients taking antihypertensive agents who have been supine for some time should be slowly raised from that position.They should dangle their legs over the side of the chair and wiggle them before rising to the standing position.

Accepted Answer

A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement is false,the second is true. 
A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement is false,the second is true.

Question 20

Which of the following agents can worsen asthma?

Accepted Answer

A) Propranolol (Inderal) 
B) Calcium channel blocker 
C) ACEIs 
D) Anticholinergics 
A) Propranolol (Inderal) 
B) Calcium channel blocker 
C) ACEIs 
D) Anticholinergics

Exam 12: Drugs for the Treatment of Cardiovascular Disease

To prevent tolerance,prophylactic nitrates should be given with at least a(n)

Which of the following statements is true of ezetimibe?

Which of the following classes of antiarrhythmics is associated with gingival enlargement?

a-Methyldopa and clonidine act in the central nervous system (CNS)as a-adrenergic antagonists.

Which is the treatment of choice for the treatment of heart failure (HF)?

There is a danger of _____ if the dose of anticoagulant is too small.

Which of the following drugs is a direct inhibitor of thrombin?

The _____ has the fastest rate of depolarization and therefore directs all the other cells of the heart.

Entresto works primarily by (Select all that apply. )

Which of the following statements is true regarding hypertension?

Which of the following categories of agents may be used to treat both hypertension and benign prostatic hypertrophy?

The use of nitroglycerin (NTG)is contraindicated if sildenafil (Viagra)has been administered within 24 hours.This is because the NTG-sildenafil combination can precipitate a hypertensive crisis.

How long should a person who has had a myocardial infarction wait before receiving dental care?

Some studies have found that the presence of periodontal disease predicts an increase in morbidity and mortality resulting from cardiovascular disease.Other studies have failed to show a relationship.

Calcium channel blockers may be used to treat which of the following? (Select all that apply. )

Niacin works by

a-Methyldopa (Aldomet)and clonidine (Catapres [TTS])act in the central nervous system (CNS)as

One can prevent an attack of angina pectoris by administering nitrous oxide.

Patients taking antihypertensive agents who have been supine for some time should be slowly raised from that position.They should dangle their legs over the side of the chair and wiggle them before rising to the standing position.

Which of the following agents can worsen asthma?

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