Question 1

An investigational new drug application (INDA)is submitted _____ trials.

Accepted Answer

A) before preclinical trials 
B) before phase 1 clinical trials 
C) after phase 2 clinical trials 
D) before phase 3 clinical trials 
A) before preclinical trials 
B) before phase 1 clinical trials 
C) after phase 2 clinical trials 
D) before phase 3 clinical trials B

Question 2

Which federal regulatory body regulates the trade practices of drug companies and prohibits false advertising of foods,nonprescription drugs,and cosmetics?

Accepted Answer

A) FDA 
B) FTC 
C) DEA 
D) OBRA 
A) FDA 
B) FTC 
C) DEA 
D) OBRA B

Question 3

How are computer and online resources enhancing printed books as a source of information about drugs? (Select all that apply. )

Accepted Answer

A) Web-based physicians can diagnose patient conditions and prescribe medication over the Internet. 
B) Tablet computers and smart phones may be used for medication information databases. 
C) Some publishers have apps that can be downloaded to smart phones. 
D) Websites such as WebMD have decision trees whereby patients can identify their own health condition and determine appropriate treatment and medication. 
E) Older editions of textbooks have been placed in the public domain and are useful for information about medications and drug interactions. 
A) Web-based physicians can diagnose patient conditions and prescribe medication over the Internet. 
B) Tablet computers and smart phones may be used for medication information databases. 
C) Some publishers have apps that can be downloaded to smart phones. 
D) Websites such as WebMD have decision trees whereby patients can identify their own health condition and determine appropriate treatment and medication. 
E) Older editions of textbooks have been placed in the public domain and are useful for information about medications and drug interactions. B,C

Question 4

Which of the following is a schedule II controlled substance?

Accepted Answer

A) Heroin 
B) Propranolol 
C) Amphetamine 
D) Dextropropoxyphene (Darvon) 
A) Heroin 
B) Propranolol 
C) Amphetamine 
D) Dextropropoxyphene (Darvon)

Question 5

Which drug legislation act was instrumental for the growth of electronic prescribing?

Accepted Answer

A) Controlled Substance Act 
B) Medicare Modernization Act 
C) Food,Drug and Cosmetic Act 
D) Harrison Narcotic Act 
A) Controlled Substance Act 
B) Medicare Modernization Act 
C) Food,Drug and Cosmetic Act 
D) Harrison Narcotic Act

Question 6

An "orphan drug" is

Accepted Answer

A) not related to any other medication currently available. 
B) developed specifically to treat a rare medical condition. 
C) a drug that has been on the market for longer than 20 years and generic substitution is permitted. 
D) no longer available for use as newer,more effective medications are available. 
A) not related to any other medication currently available. 
B) developed specifically to treat a rare medical condition. 
C) a drug that has been on the market for longer than 20 years and generic substitution is permitted. 
D) no longer available for use as newer,more effective medications are available.

Question 7

Nutritional or herbal supplements

Accepted Answer

A) carry the U.S.Food and Drug Administration (FD
A) approval for disease states. 
B) are not drugs. 
C) can cause adverse effects. 
D) will not interact with other drugs the patient may be taking. 
A) carry the U.S.Food and Drug Administration (FD
A) approval for disease states. 
B) are not drugs. 
C) can cause adverse effects. 
D) will not interact with other drugs the patient may be taking.

Question 8

The body of a prescription includes directions to the patient.

Accepted Answer

A) True 
 B)False

Question 9

Phase 1 clinical trials involve all of the following except which one?

Accepted Answer

A) Safe dose range 
B) Toxic effects of the drug 
C) Metabolism 
D) Effectiveness 
A) Safe dose range 
B) Toxic effects of the drug 
C) Metabolism 
D) Effectiveness

Question 10

What would be an advantage for a dentist to call the pharmacy with a prescription for Tylenol #3 rather than hydrocodone for a patient who calls late at night requesting medication for pain following root canal therapy?

Accepted Answer

A) Tylenol #3 is available over-the-counter and does not require a prescription. 
B) Tylenol #3 is a not a controlled substance and hydrocodone is a controlled substance. 
C) A prescription for Tylenol #3 (Schedule III)may be telephoned,whereas hydrocodone (Schedule II)requires a written prescription. 
D) Tylenol #3 has greater potency than hydrocodone. 
A) Tylenol #3 is available over-the-counter and does not require a prescription. 
B) Tylenol #3 is a not a controlled substance and hydrocodone is a controlled substance. 
C) A prescription for Tylenol #3 (Schedule III)may be telephoned,whereas hydrocodone (Schedule II)requires a written prescription. 
D) Tylenol #3 has greater potency than hydrocodone.

Question 11

The word stat on a prescription means

Accepted Answer

A) before meals. 
B) at bedtime. 
C) immediately. 
D) every. 
A) before meals. 
B) at bedtime. 
C) immediately. 
D) every.

Question 12

Knowledge of pharmacology aids the dental professional in

Accepted Answer

A) obtaining a patient's health history. 
B) administering drugs in the office. 
C) handling emergency situations. 
D) selection of a nonprescription medication. 
E) All of the above 
A) obtaining a patient's health history. 
B) administering drugs in the office. 
C) handling emergency situations. 
D) selection of a nonprescription medication. 
E) All of the above

Question 13

Which of the following is determined during a phase 3 clinical evaluation of a new drug?

Accepted Answer

A) Effectiveness 
B) Safety and efficacy 
C) Dosage 
D) Both A and B 
E) Both B and C 
A) Effectiveness 
B) Safety and efficacy 
C) Dosage 
D) Both A and B 
E) Both B and C

Question 14

Which of the following is located in the body of the prescription?

Accepted Answer

A) The date of the prescription 
B) The amount of the drug to be dispensed 
C) Directions to the prescriber 
D) Refill instructions 
A) The date of the prescription 
B) The amount of the drug to be dispensed 
C) Directions to the prescriber 
D) Refill instructions

Question 15

Two drugs that are found to be chemically equivalent,but not biologically equivalent or therapeutically equivalent are said to differ in

Accepted Answer

A) potency. 
B) efficacy. 
C) bioavailability. 
D) therapeutic index. 
A) potency. 
B) efficacy. 
C) bioavailability. 
D) therapeutic index.

Question 16

Which of the following are true of an off-label use of a drug? (Select all that apply. )

Accepted Answer

A) Prescribers are allowed to use drugs for off-label use under certain circumstances. 
B) The FDA approves the use of drugs for specific indications,which are listed or labeled on the package insert of the drug. 
C) Drug manufacturers have much useful information regarding off-label uses of their drugs on their websites. 
D) Off-label use of drugs is not permitted in the United States. 
E) Off-label drugs are repackaged for sale by clandestine organizations outside the United States and are illegal to transport or distribute. 
A) Prescribers are allowed to use drugs for off-label use under certain circumstances. 
B) The FDA approves the use of drugs for specific indications,which are listed or labeled on the package insert of the drug. 
C) Drug manufacturers have much useful information regarding off-label uses of their drugs on their websites. 
D) Off-label use of drugs is not permitted in the United States. 
E) Off-label drugs are repackaged for sale by clandestine organizations outside the United States and are illegal to transport or distribute.

Question 17

The federal body that determines whether a drug is considered a controlled substance and to which schedule it belongs is the

Accepted Answer

A) Food and Drug Administration (FD
A) . 
B) Federal Trade Commission (FT
C) . 
C) Drug Enforcement Administration (DE
A) . 
D) U.S.Pharmacopeia (USP). 
A) Food and Drug Administration (FD
A) . 
B) Federal Trade Commission (FT
C) . 
C) Drug Enforcement Administration (DE
A) . 
D) U.S.Pharmacopeia (USP).

Question 18

Which of the following are associated with increased patient nonadherence to medication therapy? (Select all that apply. )

Accepted Answer

A) Some patients may fear of the side effects of the medication. 
B) A longer duration of drug therapy is associated with the risk for nonadherence with medication therapy. 
C) Increased dosing frequency is associated with nonadherence with medication therapy. 
D) The issue of nonadherence to medication therapy is not important,as patients reliably take their medication as prescribed. 
A) Some patients may fear of the side effects of the medication. 
B) A longer duration of drug therapy is associated with the risk for nonadherence with medication therapy. 
C) Increased dosing frequency is associated with nonadherence with medication therapy. 
D) The issue of nonadherence to medication therapy is not important,as patients reliably take their medication as prescribed.

Question 19

Controlled substances in schedule _____ require a written prescription with the provider's signature and do not permit refills.

Accepted Answer

A) II,III,and IV 
B) II and III 
C) III and IV 
D) II only 
E) III only 
A) II,III,and IV 
B) II and III 
C) III and IV 
D) II only 
E) III only

Question 20

On a prescription,the directions to the patient are preceded by

Accepted Answer

A) Rx. 
B) Sig. 
C) #. 
D) Disp. 
A) Rx. 
B) Sig. 
C) #. 
D) Disp.

Exam 1: Information Sources, Regulatory Agencies, Drug Legislation, and Prescription Writing

An investigational new drug application (INDA)is submitted _____ trials.

Which federal regulatory body regulates the trade practices of drug companies and prohibits false advertising of foods,nonprescription drugs,and cosmetics?

How are computer and online resources enhancing printed books as a source of information about drugs? (Select all that apply. )

Which of the following is a schedule II controlled substance?

Which drug legislation act was instrumental for the growth of electronic prescribing?

An "orphan drug" is

Nutritional or herbal supplements

The body of a prescription includes directions to the patient.

Phase 1 clinical trials involve all of the following except which one?

What would be an advantage for a dentist to call the pharmacy with a prescription for Tylenol #3 rather than hydrocodone for a patient who calls late at night requesting medication for pain following root canal therapy?

The word stat on a prescription means

Knowledge of pharmacology aids the dental professional in

Which of the following is determined during a phase 3 clinical evaluation of a new drug?

Which of the following is located in the body of the prescription?

Two drugs that are found to be chemically equivalent,but not biologically equivalent or therapeutically equivalent are said to differ in

Which of the following are true of an off-label use of a drug? (Select all that apply. )

The federal body that determines whether a drug is considered a controlled substance and to which schedule it belongs is the

Which of the following are associated with increased patient nonadherence to medication therapy? (Select all that apply. )

Controlled substances in schedule _____ require a written prescription with the provider's signature and do not permit refills.

On a prescription,the directions to the patient are preceded by

Drug Action and Handling

Adverse Reactions

Autonomic Drugs

Nonopioid Non-Narcoticanalgesics

Opioid Narcoticanalgesics and Antagonists

Antiinfective Agents

Antifungal and Antiviral Agents

Local Anesthetics

General Anesthetics

Antianxiety Agents

Drugs for the Treatment of Cardiovascular Disease

Drugs for the Treatment of Gastrointestinal Diseases

Drugs for the Treatment of Seizure Disorders

Drugs for the Treatment of Central Nervous System Disorders

Adrenocorticosteroids

Drugs for the Treatment of Respiratory Disorders and Allergic Rhinitis

Drugs for the Treatment of Diabetes Mellitus

Drugs for the Treatment of Other Endocrine Disorders

Antineoplastic Drugs

Emergency Drugs

Pregnancy and Breast Feeding

Substance Use Disorders

Naturalherbal Products and Dietary Supplements

Oral Conditions and Their Treatment

Hygiene-Related Oral Disorders

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