Question 1

Which of the following agents is most closely associated with the development of pseudomembranous colitis as a toxicity that limits its general use?

Accepted Answer

A) Erythromycin 
B) Clindamycin 
C) Penicillin VK 
D) Metronidazole 
A) Erythromycin 
B) Clindamycin 
C) Penicillin VK 
D) Metronidazole B

Question 2

A cephalosporin would be most closely related to which of the following agents?

Accepted Answer

A) Penicillin VK 
B) Clarithromycin 
C) Ciprofloxacin 
D) Doxycycline 
E) Clindamycin 
A) Penicillin VK 
B) Clarithromycin 
C) Ciprofloxacin 
D) Doxycycline 
E) Clindamycin A

Question 3

Which of the following antibiotics is available mixed with clavulanic acid?

Accepted Answer

A) Ampicillin 
B) Amoxicillin 
C) Carbenicillin 
D) Azithromycin 
A) Ampicillin 
B) Amoxicillin 
C) Carbenicillin 
D) Azithromycin B

Question 4

Which of the following antibiotics is associated with pseudomembranous colitis?

Accepted Answer

A) Penicillin 
B) Erythromycin 
C) Clindamycin 
D) Metronidazole 
A) Penicillin 
B) Erythromycin 
C) Clindamycin 
D) Metronidazole

Question 5

Tetracyclines should not be used in children younger than _____ years of age.

Accepted Answer

A) 6 
B) 9 
C) 12 
D) 15 
A) 6 
B) 9 
C) 12 
D) 15

Question 6

Metronidazole has antiinflammatory activity.

Accepted Answer

A) True 
 B)False

Question 7

Which of the following conditions is the most common adverse reaction from the administration of erythromycin?

Accepted Answer

A) Anaphylaxis 
B) Skin rash 
C) Gastrointestinal effects 
D) Miosis 
A) Anaphylaxis 
B) Skin rash 
C) Gastrointestinal effects 
D) Miosis

Question 8

The frequency of cross-hypersensitivity between penicillin and cephalosporins is about __%.

Accepted Answer

A) 0 
B) 10 
C) 20 
D) 30 
E) 40 
A) 0 
B) 10 
C) 20 
D) 30 
E) 40

Question 9

The drug whose future use may include organisms found in periodontal disease is

Accepted Answer

A) ofloxacin. 
B) sulfamethoxazole. 
C) macrodantin. 
D) streptomycin. 
A) ofloxacin. 
B) sulfamethoxazole. 
C) macrodantin. 
D) streptomycin.

Question 10

Infective endocarditis prophylaxis with an antiinfective is indicated for patients who have had

Accepted Answer

A) coronary artery bypass surgery. 
B) a prosthetic heart valve. 
C) functional murmur. 
D) a cardiac pacemaker. 
A) coronary artery bypass surgery. 
B) a prosthetic heart valve. 
C) functional murmur. 
D) a cardiac pacemaker.

Question 11

Which of the following periodontal diseases is usually not treated with antimicrobials?

Accepted Answer

A) Periodontal abscess 
B) Localized juvenile periodontitis 
C) Adult periodontitis 
D) Rapidly advancing periodontitis 
A) Periodontal abscess 
B) Localized juvenile periodontitis 
C) Adult periodontitis 
D) Rapidly advancing periodontitis

Question 12

Penicillinase inactivates the penicillin moiety by

Accepted Answer

A) sublimation. 
B) desiccation. 
C) cleaving the b-lactam ring. 
D) cleaving the S-containing thiazolidine ring. 
A) sublimation. 
B) desiccation. 
C) cleaving the b-lactam ring. 
D) cleaving the S-containing thiazolidine ring.

Question 13

Which of the following choices is the dental hygienist's biggest dental problem in the adult patient?

Accepted Answer

A) Caries 
B) Periodontal disease 
C) Localized dental infection 
D) Systemic dental infection 
A) Caries 
B) Periodontal disease 
C) Localized dental infection 
D) Systemic dental infection

Question 14

Large doses of cephalosporins often produce a Coombs reaction,which means

Accepted Answer

A) high blood pressure is exacerbated. 
B) the immune mechanism is attacking the patient's own red blood cells. 
C) degeneration of neural glial cells occurs. 
D) nephritis of the kidneys occurs. 
A) high blood pressure is exacerbated. 
B) the immune mechanism is attacking the patient's own red blood cells. 
C) degeneration of neural glial cells occurs. 
D) nephritis of the kidneys occurs.

Question 15

The disease-producing power of the microorganism is called

Accepted Answer

A) resistance. 
B) superinfection. 
C) infection. 
D) virulence. 
A) resistance. 
B) superinfection. 
C) infection. 
D) virulence.

Question 16

Antiinfectives are not needed in oral cavity infections if drainage of the infected area can be established.

Accepted Answer

A) True 
 B)False

Question 17

Which of the following statements is true concerning the pharmacokinetics of penicillin?

Accepted Answer

A) Penicillin may be administered orally,parenterally,or topically. 
B) Penicillin G is better absorbed orally than penicillin V;thus,penicillin G is used for administration of oral penicillin. 
C) Penicillin V and amoxicillin can be taken without regard to meals. 
D) Penicillin does not cross the placenta and will not appear in breast milk. 
A) Penicillin may be administered orally,parenterally,or topically. 
B) Penicillin G is better absorbed orally than penicillin V;thus,penicillin G is used for administration of oral penicillin. 
C) Penicillin V and amoxicillin can be taken without regard to meals. 
D) Penicillin does not cross the placenta and will not appear in breast milk.

Question 18

When a patient with a stage 1 infection is allergic to penicillin V,the best alternative would be

Accepted Answer

A) penicillin G or ampicillin. 
B) erythromycin ethylsuccinate or clindamycin. 
C) tetracycline or metronidazole. 
D) vancomycin. 
A) penicillin G or ampicillin. 
B) erythromycin ethylsuccinate or clindamycin. 
C) tetracycline or metronidazole. 
D) vancomycin.

Question 19

Which of the following statements are true concerning antibiotic-resistant infections? (Select all that apply. )

Accepted Answer

A) More than 10% of patients with antibiotic-resistant infections in the United States each year will die from their infection. 
B) Natural resistance occurs when an organism that was previously sensitive to an antimicrobial agent develops resistance. 
C) Microbial organisms have the ability to transfer genetic material from one to another so that an organism may become resistant to an antibiotic without ever having been exposed to the antibiotic. 
D) The development of new antibiotics has greatly reduced the number of antibiotic-resistant bacteria over the past 10 years. 
A) More than 10% of patients with antibiotic-resistant infections in the United States each year will die from their infection. 
B) Natural resistance occurs when an organism that was previously sensitive to an antimicrobial agent develops resistance. 
C) Microbial organisms have the ability to transfer genetic material from one to another so that an organism may become resistant to an antibiotic without ever having been exposed to the antibiotic. 
D) The development of new antibiotics has greatly reduced the number of antibiotic-resistant bacteria over the past 10 years.

Question 20

Superinfection is more often caused by _____-spectrum antibiotics and increases when taken for a _____ time period.

Accepted Answer

A) narrow;shorter 
B) narrow;longer 
C) broad;shorter 
D) broad;longer 
A) narrow;shorter 
B) narrow;longer 
C) broad;shorter 
D) broad;longer

Exam 7: Antiinfective Agents

Which of the following agents is most closely associated with the development of pseudomembranous colitis as a toxicity that limits its general use?

A cephalosporin would be most closely related to which of the following agents?

Which of the following antibiotics is available mixed with clavulanic acid?

Which of the following antibiotics is associated with pseudomembranous colitis?

Tetracyclines should not be used in children younger than _____ years of age.

Metronidazole has antiinflammatory activity.

Which of the following conditions is the most common adverse reaction from the administration of erythromycin?

The frequency of cross-hypersensitivity between penicillin and cephalosporins is about __%.

The drug whose future use may include organisms found in periodontal disease is

Infective endocarditis prophylaxis with an antiinfective is indicated for patients who have had

Which of the following periodontal diseases is usually not treated with antimicrobials?

Penicillinase inactivates the penicillin moiety by

Which of the following choices is the dental hygienist's biggest dental problem in the adult patient?

Large doses of cephalosporins often produce a Coombs reaction,which means

The disease-producing power of the microorganism is called

Antiinfectives are not needed in oral cavity infections if drainage of the infected area can be established.

Which of the following statements is true concerning the pharmacokinetics of penicillin?

When a patient with a stage 1 infection is allergic to penicillin V,the best alternative would be

Which of the following statements are true concerning antibiotic-resistant infections? (Select all that apply. )

Superinfection is more often caused by _____-spectrum antibiotics and increases when taken for a _____ time period.

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