Question 1

_____ are the first orally active agents against certain Pseudomonas species.

Accepted Answer

A) Aminoglycosides 
B) Sulfonamides 
C) Quinolones 
D) Tetracyclines 
A) Aminoglycosides 
B) Sulfonamides 
C) Quinolones 
D) Tetracyclines

Question 2

Dental caries is caused by an infection with

Accepted Answer

A) Porphyromonas gingivalis. 
B) Eikenella corrodens. 
C) Streptococcus mutans. 
D) Fusobacterium. 
A) Porphyromonas gingivalis. 
B) Eikenella corrodens. 
C) Streptococcus mutans. 
D) Fusobacterium.

Question 3

The American Dental Association (ADA)and the American Academy of Orthopedic Surgeons (AAOS)recommend for dentists to prescribe antibiotic prophylaxis for patients with joint replacements.The American Dental Association Council on Scientific Affairs demonstrated the benefits of antibiotic prophylaxis outweigh potential harm.

Accepted Answer

A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second statement is false. 
D) The first statement is false,the second statement is true. 
A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second statement is false. 
D) The first statement is false,the second statement is true.

Question 4

Which of the following statements is true of the tetracyclines?

Accepted Answer

A) They are bactericidal. 
B) Tetracyclines interfere with the synthesis of bacterial protein by binding at the 50S subunit of bacterial ribosomes. 
C) In the study of sensitivity or organisms isolated from dental infections,one-fifth to two-fifths of Staphylococcus aureus (S.aureus)were found to be resistant to tetracycline. 
D) Tetracyclines are not prone to enterohepatic circulation. 
A) They are bactericidal. 
B) Tetracyclines interfere with the synthesis of bacterial protein by binding at the 50S subunit of bacterial ribosomes. 
C) In the study of sensitivity or organisms isolated from dental infections,one-fifth to two-fifths of Staphylococcus aureus (S.aureus)were found to be resistant to tetracycline. 
D) Tetracyclines are not prone to enterohepatic circulation.

Question 5

Which of the following groups of penicillins are most commonly used in dentistry? (Select all that apply. )

Accepted Answer

A) Penicillin G and V 
B) Penicillinase-resistant penicillins 
C) Amoxicillin 
D) Extended-spectrum penicillins 
A) Penicillin G and V 
B) Penicillinase-resistant penicillins 
C) Amoxicillin 
D) Extended-spectrum penicillins

Question 6

Both the American Dental Association (ADA)and the American Academy of Orthopedic Surgeons (AAOS)recommend that which type of patients with joint replacements should receive antibiotic prophylaxis before dental procedures that can lead to bacteremia?

Accepted Answer

A) All patients for the rest of their lives. 
B) All patients for 2 years. 
C) Patients with weakened immune systems. 
D) No patients. 
A) All patients for the rest of their lives. 
B) All patients for 2 years. 
C) Patients with weakened immune systems. 
D) No patients.

Question 7

Which of the following antimicrobial agents is associated with ototoxicity?

Accepted Answer

A) Vancomycin 
B) Aminoglycosides 
C) Nitrofurantoin 
D) Quinolones 
A) Vancomycin 
B) Aminoglycosides 
C) Nitrofurantoin 
D) Quinolones

Question 8

Which of the following statements is true concerning infection and host resistance?

Accepted Answer

A) Host resistance should be considered as having both local and systemic components. 
B) If a patient has diabetes mellitus it can reduce the resistance to an infection. 
C) Drugs such as steroids are capable of enhancing a patient's immune response. 
D) Both A and B 
E) Both B and C 
A) Host resistance should be considered as having both local and systemic components. 
B) If a patient has diabetes mellitus it can reduce the resistance to an infection. 
C) Drugs such as steroids are capable of enhancing a patient's immune response. 
D) Both A and B 
E) Both B and C

Question 9

An erythematous rash on the face and upper body known as red man syndrome is associated with use of which of the following antimicrobial agents?

Accepted Answer

A) Augmentin 
B) Metronidazole 
C) Vancomycin 
D) Chloramphenicol 
A) Augmentin 
B) Metronidazole 
C) Vancomycin 
D) Chloramphenicol

Question 10

Which of the following agents is the drug of first choice against infections caused by aerobic microorganisms in penicillin-allergic patients?

Accepted Answer

A) Metronidazole 
B) Erythromycin 
C) Doxycycline 
D) Clindamycin 
A) Metronidazole 
B) Erythromycin 
C) Doxycycline 
D) Clindamycin

Question 11

Which of the following statements is true of vancomycin?

Accepted Answer

A) Vancomycin is related to the cephalosporins. 
B) Vancomycin is usually administered only intravenously for a systemic effect. 
C) Vancomycin is bacteriostatic. 
D) Vancomycin has a broad spectrum of action against a wide variety of gram-positive and gram-negative organisms. 
A) Vancomycin is related to the cephalosporins. 
B) Vancomycin is usually administered only intravenously for a systemic effect. 
C) Vancomycin is bacteriostatic. 
D) Vancomycin has a broad spectrum of action against a wide variety of gram-positive and gram-negative organisms.

Question 12

Which of the following statements is true concerning the pharmacokinetics of erythromycin?

Accepted Answer

A) Erythromycin is broken down in gastric fluid and absorbed through the stomach wall. 
B) Erythromycin is not available in a topical preparation because of allergenicity. 
C) Erythromycin is available in oral but not injectable forms. 
D) Erythromycin should be administered 2 hours before or 2 hours after meals. 
A) Erythromycin is broken down in gastric fluid and absorbed through the stomach wall. 
B) Erythromycin is not available in a topical preparation because of allergenicity. 
C) Erythromycin is available in oral but not injectable forms. 
D) Erythromycin should be administered 2 hours before or 2 hours after meals.

Question 13

Which of the following antiinfective agents is bacteriostatic,but may be bactericidal at higher dose levels?

Accepted Answer

A) Cephalosporins 
B) Metronidazole 
C) Penicillins 
D) Erythromycin 
E) Vancomycin 
A) Cephalosporins 
B) Metronidazole 
C) Penicillins 
D) Erythromycin 
E) Vancomycin

Question 14

Prophylactic antibiotics are recommended for which procedure? (Select all that apply. )

Accepted Answer

A) Dental x-ray images 
B) Routine injections of dental anesthetic 
C) Dental prophylaxis 
D) Placement of orthodontic brackets 
E) Periodontal probing 
A) Dental x-ray images 
B) Routine injections of dental anesthetic 
C) Dental prophylaxis 
D) Placement of orthodontic brackets 
E) Periodontal probing

Question 15

_____ has the highest incidence of gastrointestinal complaints of any of the antibiotics.

Accepted Answer

A) Penicillin 
B) Erythromycin 
C) Clindamycin 
D) Cephalosporin 
A) Penicillin 
B) Erythromycin 
C) Clindamycin 
D) Cephalosporin

Question 16

Clavulanic acid is

Accepted Answer

A) a bacteriostatic antibiotic. 
B) a bactericidal antibiotic. 
C) a b-lactamase inhibitor. 
D) Both A and C 
E) Both B and C 
A) a bacteriostatic antibiotic. 
B) a bactericidal antibiotic. 
C) a b-lactamase inhibitor. 
D) Both A and C 
E) Both B and C

Question 17

Aminoglycosides

Accepted Answer

A) are bacteriostatic. 
B) are used primarily to treat aerobic gram-negative infections when other agents are ineffective. 
C) are indicated for stage 1 infections. 
D) inhibit cell wall synthesis. 
A) are bacteriostatic. 
B) are used primarily to treat aerobic gram-negative infections when other agents are ineffective. 
C) are indicated for stage 1 infections. 
D) inhibit cell wall synthesis.

Question 18

Which of the following statements is true regarding penicillin allergy?

Accepted Answer

A) Allergic reactions with oral penicillin are more common than with parenteral penicillin. 
B) Anaphylactic reactions are more frequent in patients pretreated with b-blockers and subsequently given oral penicillin. 
C) The treatment of anaphylaxis caused by penicillin is the immediate administration of corticosteroids. 
D) Estimates indicate that 10,000 to 30,000 deaths occur annually in the United States because of an allergic reaction to penicillin. 
A) Allergic reactions with oral penicillin are more common than with parenteral penicillin. 
B) Anaphylactic reactions are more frequent in patients pretreated with b-blockers and subsequently given oral penicillin. 
C) The treatment of anaphylaxis caused by penicillin is the immediate administration of corticosteroids. 
D) Estimates indicate that 10,000 to 30,000 deaths occur annually in the United States because of an allergic reaction to penicillin.

Question 19

An _____ agent is a substance that destroys or suppresses the growth or multiplication of bacteria.

Accepted Answer

A) antiinfective 
B) antibacterial 
C) antibiotic 
D) antimicrobial 
A) antiinfective 
B) antibacterial 
C) antibiotic 
D) antimicrobial

Question 20

If a patient requires premedication with antibiotics before a dental procedure and he or she is allergic to penicillins or ampicillin but can take oral medication,the drug of choice is

Accepted Answer

A) tetracycline. 
B) metronidazole. 
C) cephalexin. 
D) amoxicillin. 
A) tetracycline. 
B) metronidazole. 
C) cephalexin. 
D) amoxicillin.

Exam 7: Antiinfective Agents

_____ are the first orally active agents against certain Pseudomonas species.

Dental caries is caused by an infection with

Which of the following statements is true of the tetracyclines?

Which of the following groups of penicillins are most commonly used in dentistry? (Select all that apply. )

Both the American Dental Association (ADA)and the American Academy of Orthopedic Surgeons (AAOS)recommend that which type of patients with joint replacements should receive antibiotic prophylaxis before dental procedures that can lead to bacteremia?

Which of the following antimicrobial agents is associated with ototoxicity?

Which of the following statements is true concerning infection and host resistance?

An erythematous rash on the face and upper body known as red man syndrome is associated with use of which of the following antimicrobial agents?

Which of the following agents is the drug of first choice against infections caused by aerobic microorganisms in penicillin-allergic patients?

Which of the following statements is true of vancomycin?

Which of the following statements is true concerning the pharmacokinetics of erythromycin?

Which of the following antiinfective agents is bacteriostatic,but may be bactericidal at higher dose levels?

Prophylactic antibiotics are recommended for which procedure? (Select all that apply. )

_____ has the highest incidence of gastrointestinal complaints of any of the antibiotics.

Clavulanic acid is

Aminoglycosides

Which of the following statements is true regarding penicillin allergy?

An _____ agent is a substance that destroys or suppresses the growth or multiplication of bacteria.

If a patient requires premedication with antibiotics before a dental procedure and he or she is allergic to penicillins or ampicillin but can take oral medication,the drug of choice is

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